Catherine Cresson

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Catherine Cresson (BE postdoctoral) in collaboration with Prof. Dane Wittrup (BE/ChE, MIT) and Prof. Steve Wiley (PNL)

Quantitative investigations of the most common mutation of the EGF receptor, EGFRvIII. Studies include both experimental and computational approaches to determining trafficking, signaling, and cellular responses under a range of EGFRvIII expression levels and the effects of antibody based therapeutics on altering those behaviors.