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Kostov, Y., Gryczynski, Z., Rao, G. (2002) Polarization oxygen sensor: a template for a new class of fluorescence-based sensors. Anal. Chem. 74, 2167-2171.
We describe a novel oxygen polarization sensor based on a single molecule that changes the observed anisotropy of its emission with variation of the oxygen concentration. The approach is demonstrated both in solution and in solid films. A simple mathematical description of the sensor is included and experimentally verified. The technique demonstrated here creates opportunity for development of a new class of polarization-based dyes and sensors.