Biomod/2014/acknowledgement.html

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  	    <li class='active '><a href="http://openwetware.org/wiki/Biomod/2014/Tianjin"><span>Home</span></a></li>
  	    <li class='has-sub'><a href="http://openwetware.org/wiki/Biomod/2014/wiki-2%27.html"><span>Idea</span></a>
  	        <ul>
  	            <li><a href='http://openwetware.org/wiki/Biomod/2014/wiki-2%27.html#motivation'><span>Background</span></a></li>
                   <li><a href='http://openwetware.org/wiki/Biomod/2014/wiki-2%27.html#design'><span>Motivation</span></a></li>
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           <li class='has-sub'><a href="http://openwetware.org/wiki/Biomod/2014/experiment.html"><span>Project</span></a>
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  	            <li><a href='http://openwetware.org/wiki/Biomod/2012/Tianjin/Result/LogicGate'><span>Strand Replacement Reaction</span></a></li>
                   <li><a href='http://openwetware.org/wiki/Biomod/2012/Tianjin/Result/YDNA'><span> Synthesis of AU-DNA-CY3</span></a></li>
                   <li><a href='http://openwetware.org/wiki/Biomod/2012/Tianjin/Result/Origami'><span>DNA Origami</span></a></li>
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           <li class='active'><a href="http://openwetware.org/wiki/Biomod/2014/result.html"><span>Protocol</span></a> 

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           <li class='active '><a href="http://openwetware.org/wiki/Biomod/2014/members.html"><span>Members and Acknowledgement</span></a>
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<div id="apDiv7"> <p><span class="ys02">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Abstract</span></br> &nbsp;

Recently&nbsp;we&nbsp;designed&nbsp;a&nbsp;complex&nbsp;drug&nbsp;delivery&nbsp;</p>

<p> system&nbsp;named&nbsp;DNA&nbsp;spaceship&nbsp;for&nbsp;tumor&nbsp;therapy.&nbsp;</p> <p> The main&nbsp;body&nbsp;of&nbsp;our&nbsp;DNA&nbsp;spaceship&nbsp;is&nbsp;DNA&nbsp;</p> <p> origami&nbsp;and&nbsp;drugs&nbsp;are loaded&nbsp;inside.&nbsp;Magnetic&nbsp;</p> <p> nanoparticles(Fe<sub>3</sub>O<sub>4</sub>)&nbsp;are&nbsp;modified&nbsp;on&nbsp;our&nbsp;DNA&nbsp;</p> <p> origami&nbsp;to&nbsp;control&nbsp;the&nbsp;transportation&nbsp;of&nbsp;the&nbsp;DNA&nbsp;</p> <p> origami&nbsp;more&nbsp;precisely&nbsp;by&nbsp;applying&nbsp;magnetic&nbsp;field.&nbsp;</p> <p> The&nbsp;opening&nbsp;of&nbsp;DNA&nbsp;origami&nbsp;(release&nbsp;of&nbsp;drugs&nbsp;</p> <p> inside)&nbsp;is&nbsp;controlled&nbsp;by&nbsp;light&nbsp;signal.&nbsp;We&nbsp;could&nbsp;use&nbsp;</p> <p> light&nbsp;signals&nbsp;of&nbsp;varying&nbsp;intensity&nbsp;to&nbsp;open&nbsp;different&nbsp;</p> <p> DNA&nbsp;origamis&nbsp;and&nbsp;release&nbsp;different&nbsp;drugs.&nbsp;This&nbsp;</p> <p> kind&nbsp;of&nbsp;light&nbsp;control&nbsp;is&nbsp;achieved&nbsp;by&nbsp;Au&nbsp;</p> <p> nanoparticles&nbsp;modified&nbsp;on&nbsp;DNA&nbsp;origami.&nbsp;In&nbsp;</p> <p> conclusion,&nbsp;drugs&nbsp;can&nbsp;be&nbsp;precisely&nbsp;delivered&nbsp;to&nbsp;the&nbsp;</p> <p> tumor&nbsp;cells&nbsp;without damaging&nbsp;normal&nbsp;cells&nbsp;and</p> <p> drug&nbsp;release&nbsp;is&nbsp;controlled&nbsp;by&nbsp;light&nbsp;signal.</br> </p>

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