BioNumbers data base

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ID Property family Property subfamily Property Organism Value Units Reference (where data was taken from) Primary source of reference (if different from previous) Keywords measurement method Standard deviation or range if available comments (cell type, measurement conditions etc.) Entered by:
1 Sizes Lengths Cell length E. coli 2 microns http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi Shan Sundararaj, Anchi Guo, Bahram Habibi-Nazhad, Melania Rouani,Paul Stothard, Michael Ellison,and David S. Wishart "The CyberCell Database (CCDB): a comprehensive, self-updating, relational database to coordinate and facilitate in silico modeling of Escherichia coli" Nucleic Acids Res. 2004 January 1; 32 (Database issue): D293.D295 A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
2 Sizes Lengths Cell diameter E. coli 0.8 microns http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
3 Sizes Volumes Cell total volume E. coli 1x10-18 m^3 http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
4 Sizes Volumes Cell total volume E. coli 0.44-1.79*10^-18 m^3 Determination of bacterial cell volume with the Coulter Counter. HE Kubitschek, JA Friske - Journal of Bacteriology, 1986, p. 1466-1467 Coulter counter value depends on medium and growth rate, see ref. Ron Milo
5 Sizes Volumes Cell aqueous volume E. coli 7 x 10-16 L http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
6 Sizes Surface Cell surface area E. coli 6x10-12 m^2 http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
7 Sizes Weights Cell wet weight E. coli 1x10-15 kg http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
8 Sizes Weights Cell dry weight E. coli 3.0x10-16 kg http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
9 Sizes Weights Cell dry weight E. coli 6.4x10-16 kg Bremer, H., Dennis, P. P. (1996) Modulation of chemical composition and other parameters of the cell by growth rate. Neidhardt, et al. eds. Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97, Table 2 Indirect calculation based on the ratio: (dry mass)/OD460 calculated based on data at 30 minutes cell division time. For other division times see reference. Ron Milo
10 Sizes Volumes Periplasm volume E. coli 6.5x10-17 L http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
11 Sizes Volumes Cytoplasm volume E. coli 6.7x10-16 L http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
12 Sizes Volumes Envelope volume E. coli 1.6x10-16 L http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
13 Sizes Volumes Nuclear (DNA+protein) volume E. coli 1.6x10-16 L http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
14 Sizes Lengths Inner Membrane thickness E. coli 8x10-9 m http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
15 Sizes Lengths Outer Membrane thickness E. coli 8x10-9 - 15x10-9 m http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
16 Sizes Lengths Periplasm thickness E. coli 1x10-8 m http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
17 Sizes Sizes Average size of protein E. coli 360 aa http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
18 Sizes Lengths Average diameter of ave. protein E. coli 5 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
19 Sizes Weights Average MW of protein E. coli 40 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
20 Sizes Complexes Average prot. oligomerization state E. coli 4 proteins/complex http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
21 Sizes Weights Average MW of protein entity E. coli 160 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
22 Sizes mRNA Average size of mRNA E. coli 1100 bp http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
23 Sizes mRNA Average length of mRNA E. coli 370 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
24 Sizes Weights Average MW of all RNAs E. coli 400 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
25 Sizes Weights Average MW of single DNA E. coli 3.0x10^6 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
26 Sizes Weights Average MW of all DNA E. coli 7x10^6 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
27 Sizes Lengths Average length of DNA (chrom.) E. coli 1.55 mm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
28 Sizes Lengths Diameter of chromosome E. coli 490 micron http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
29 Sizes Lengths Diameter of condensed chromosome E. coli 17 micron http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
30 Sizes Lengths Spacing between small organics E. coli 3.6 nm/molecule http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
31 Sizes Lengths Spacing between ions E. coli 2.1 nm/molecule http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
32 Sizes Lengths Ave. spacing between proteins E. coli 7 nm/molecule http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
33 Sizes Lengths Spacing between protein entities E. coli 9 nm/molecule http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
34 General Statistics Velocities Mean Velocity of 70 kD protein (cytoplasm) E. coli 3 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
35 General Statistics Velocities Mean Velocity of 40 kD protein (cytoplasm) E. coli 5 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
36 General Statistics Velocities Mean Velocity of 30 kD protein (cytoplasm) E. coli 7 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
37 General Statistics Velocities Mean Velocity of 14 kD protein (cytoplasm) E. coli 10 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
38 General Statistics Velocities Mean Velocity of small molecules (cytoplasm) E. coli 50 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
39 General Statistics Velocities Mean Velocity of protein in H2O E. coli 27 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
40 General Statistics Velocities Mean Velocity of small molecules in H2O E. coli 87 nm/ms http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
41 General Statistics Concentrations Concentration of protein in cell E. coli 200-320 mg/ml http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
42 General Statistics Concentrations Concentration of RNA in cell E. coli 75-120 mg/ml http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
43 General Statistics Concentrations Concentration of DNA in cell E. coli 11 - 18 mg/ml http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
44 General Statistics Volumes Volume occupied by water E. coli 70 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
45 General Statistics Volumes Volume occupied by protein E. coli 17 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
46 General Statistics Volumes Volume occupied by all RNA E. coli 6 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
47 General Statistics Volumes Volume occupied by rRNA E. coli 5 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
48 General Statistics Volumes Volume occupied by tRNA E. coli 0.8 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
49 General Statistics Volumes Volume occupied by mRNA E. coli 0.2 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
50 General Statistics Volumes Volume occupied by DNA E. coli 1 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
51 General Statistics Volumes Volume occupied by ribosomes E. coli 8 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
52 General Statistics Volumes Volume occupied by lipid E. coli 3 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
53 General Statistics Volumes Volume occupied by LPS E. coli 1 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
54 General Statistics Volumes Volume occupied by murein E. coli 1 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
55 General Statistics Volumes Volume occupied by glycogen E. coli 1 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
56 General Statistics Volumes Volume occupied by ions E. coli 0.3 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
57 General Statistics Volumes Volume occupied by small organics E. coli 1 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
58 General Statistics Rates Translation rate E. coli 40 aa/sec http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
59 General Statistics Rates Translation rate E. coli 20 aa/sec Bremer, H., Dennis, P. P. (1996) Modulation of chemical composition and other parameters of the cell by growth rate. Neidhardt, et al. eds. Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97, Table 3 Dennis, P. P., and H. Bremer. 1974. Differential rate of ribosomal protein synthesis in Escherichia coli B/r. J. Mol. Biol. 84:407�$-1òó422.;Dennis, P. P., and M. Nomura. 1974. Stringent control of ribosomal protein gene expression in Escherichia coli. Proc. Natl. Acad. Sci. USA 71:3819òó3823. Indirect calculation based on the number of ribosomes, ribosome activity fraction and protein synthesis rate calculated based on data at 30 minutes cell division time. For other division times see reference. This value is probably an underestimate based on some newer results Ron Milo
60 General Statistics Rates RNA polymerase transcription rate E. coli 70 nt/sec http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi coli B/r. J. Mol. Biol. 84:407�$-1òó422. Ron Milo, Paul Jorgensen, Mike Springer
61 Copy numbers Large Molecule Copy Numbers Number of cell walls/cell E. coli 1 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
62 Copy numbers Large Molecule Copy Numbers Number of membranes/cell E. coli 2 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
63 Copy numbers Large Molecule Copy Numbers Number of chromosomes/cell E. coli 2.3 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference at mid log phase Ron Milo, Paul Jorgensen, Mike Springer
64 Copy numbers Large Molecule Copy Numbers Number of mRNA/cell E. coli 4000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
65 Copy numbers Large Molecule Copy Numbers Number of rRNA/cell E. coli 18000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
66 Copy numbers Large Molecule Copy Numbers Number of tRNA/cell E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
67 Copy numbers Large Molecule Copy Numbers Number of all RNA/cell E. coli 222000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
68 Copy numbers Large Molecule Copy Numbers Number of polysaccharides/cell E. coli 39000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
69 Copy numbers Large Molecule Copy Numbers Number of murein molecules/cell E. coli 240,000-700,000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
70 Copy numbers Large Molecule Copy Numbers Number of lipopolysaccharide/cell E. coli 600000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
71 Copy numbers Large Molecule Copy Numbers Number of lipids/cell E. coli 25000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
72 Copy numbers Large Molecule Copy Numbers Number of all lipids/cell E. coli 25000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
73 Copy numbers Large Molecule Copy Numbers Number of phosphatidylethanolamine E. coli 18500000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
74 Copy numbers Large Molecule Copy Numbers Number of phosphatidylglycerol E. coli 5000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
75 Copy numbers Large Molecule Copy Numbers Number of cardiolipin E. coli 1200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
76 Copy numbers Large Molecule Copy Numbers Number of phosphatidylserine E. coli 500000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
77 Copy numbers Large Molecule Copy Numbers Number of LPS (MW = 10kD) E. coli 600000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
78 Copy numbers Large Molecule Copy Numbers Average SA of lipid molecule E. coli 25 Ang2 http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
79 Copy numbers Large Molecule Copy Numbers Fraction of lipid bilayer=lipid E. coli 40 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
80 Copy numbers Large Molecule Copy Numbers Fraction of lipid bilayer=protein E. coli 60 Percent http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
81 Copy numbers Large Molecule Copy Numbers Number of outer membrane proteins E. coli 300000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
82 Copy numbers Large Molecule Copy Numbers Number of porins (subset of OM) E. coli 60000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
83 Copy numbers Large Molecule Copy Numbers Number of lipoproteins (OM) E. coli 240000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
84 Copy numbers Large Molecule Copy Numbers Number of inner membrane proteins E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
85 Copy numbers Large Molecule Copy Numbers Number of nuclear proteins E. coli 100000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
86 Copy numbers Large Molecule Copy Numbers Number of cytoplasmic proteins E. coli 1000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference excluding ribosomal proteins Ron Milo, Paul Jorgensen, Mike Springer
87 Copy numbers Large Molecule Copy Numbers Number of ribosomal proteins E. coli 900000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
88 Copy numbers Large Molecule Copy Numbers Number of periplasmic proteins E. coli 80000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
89 Copy numbers Large Molecule Copy Numbers Number of all proteins in cell E. coli 2600000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
90 Copy numbers Large Molecule Copy Numbers Number of all proteins in cell in amino acids E. coli 1.89*10^9 amino acids Neidhardt, F.C. et al. (1987) Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97, Table 2 For a cell cycle of 30 minutes at 37deg, see reference for value at other division rates Ron Milo
91 Genome Replication Time to replicate the chromosome E. coli 40-67 Minutes Neidhardt, F.C. et al. (1987) Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97, Table 1, 3 Value in range depends on division rate Ron Milo
92 Translation Ribosomes Average distance between ribosomes on mRNA E. coli 41-79 nucleotides Neidhardt, F.C. et al. (1987) Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97, Table 3 Indirectly calculated from other parameters, see reference Value in range depends on division rate Ron Milo
93 Copy numbers Large Molecule Copy Numbers Number of external proteins (flag/pili) E. coli 1000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
94 Copy numbers Large Molecule Copy Numbers Number of all proteins E. coli 3600000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
95 Complexes Statistics on Larger Molecule Complexes Number of protein types to make flagella E. coli 42 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
96 Sizes Statistics on Larger Molecule Complexes Length of flagella E. coli 10 - 20 microns http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
97 Sizes Statistics on Larger Molecule Complexes Diameter of flagella E. coli 25 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
98 Complexes Statistics on Larger Molecule Complexes Number of protofilaments in flagellum E. coli 11 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
99 Sizes Statistics on Larger Molecule Complexes Diameter of each fliC monomer E. coli 5 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
100 Copy numbers Statistics on Larger Molecule Complexes Number of fliC monomers in filament E. coli 33000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
101 Copy numbers Statistics on Larger Molecule Complexes Number of flagella/cell E. coli 10 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
102 Copy numbers Statistics on Larger Molecule Complexes Number of fliC proteins E. coli 330000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
103 Velocities Statistics on Larger Molecule Complexes Speed at which E. coli move E. coli 50 micron/sec http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
104 Statistics on Larger Molecule Complexes Number of protein types to make pilus E. coli 1 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
105 Lengths Statistics on Larger Molecule Complexes Length of pili/fimbrae E. coli 200-2000 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
106 Lengths Statistics on Larger Molecule Complexes Diamter of pili E. coli 6.5 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
107 Copy numbers Statistics on Larger Molecule Complexes Number of papA/nm pilus E. coli 1.5 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
108 Copy numbers Statistics on Larger Molecule Complexes Number of papA monomers/pilus E. coli 3000-30,000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
109 Copy numbers Statistics on Larger Molecule Complexes Number of pili/cell E. coli 100-300 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
110 Copy numbers Statistics on Larger Molecule Complexes Number of papA/cell E. coli 300,000-900,000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
111 Copy numbers Statistics on Larger Molecule Complexes Number of ribosomes/cell E. coli 18000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
112 Copy numbers Statistics on Larger Molecule Complexes Number of protein types to make ribosome E. coli 55 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
113 Copy numbers Statistics on Larger Molecule Complexes Number rRNA types to make ribosome E. coli 3 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
114 Copy numbers Statistics on Larger Molecule Complexes Number of proteins in 30S subunit E. coli 21 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
115 Copy numbers Statistics on Larger Molecule Complexes Number of proteins in 50S subunit E. coli 34 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
116 Copy numbers Statistics on Larger Molecule Complexes Number of rRNA in 30S subunit E. coli 1 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
117 Copy numbers Statistics on Larger Molecule Complexes Number of rRNA in 50S subunit E. coli 2 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
118 Lengths Statistics on Larger Molecule Complexes Length of all rRNA E. coli 5520 nt http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
119 Weights Statistics on Larger Molecule Complexes MW of ribosome E. coli 2700 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
120 Weights Statistics on Larger Molecule Complexes MW of RNA component E. coli 1700 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
121 Weights Statistics on Larger Molecule Complexes MW of protein component E. coli 1000 kDalton http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
122 Lengths Statistics on Larger Molecule Complexes Diameter of ribosome E. coli 20 nm http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
123 Volumes Statistics on Larger Molecule Complexes Volume of ribosome E. coli 4.2 x 10^-24 m^3 http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
124 Copy numbers Small Molecule Copy Numbers Number of water molecules/cell E. coli 2.34x10^10 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
125 Copy numbers Small Molecule Copy Numbers Number of ions/cell E. coli 120000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 120,000,000 (300 mM) Ron Milo, Paul Jorgensen, Mike Springer
126 Copy numbers Small Molecule Copy Numbers Number of small organics/cell E. coli 18000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 18,000,000 (40-50 mM) Ron Milo, Paul Jorgensen, Mike Springer
127 Copy numbers Small Molecule Copy Numbers Number of K ions E. coli 90000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 90,000,000 (200-250 mM) Ron Milo, Paul Jorgensen, Mike Springer
128 Copy numbers Small Molecule Copy Numbers Number of Na ions E. coli 2000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 2,000,000 (5 mM) Ron Milo, Paul Jorgensen, Mike Springer
129 Copy numbers Small Molecule Copy Numbers Na (in): Na (out) E. coli 1 : 20 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1:20 (in concentration) Ron Milo, Paul Jorgensen, Mike Springer
130 Copy numbers Small Molecule Copy Numbers Number of Ca ions E. coli 2300000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 2,300,000 (6 mM) Ron Milo, Paul Jorgensen, Mike Springer
131 Copy numbers Small Molecule Copy Numbers Number of free Ca ions E. coli 40 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 40 (100 nM) Ron Milo, Paul Jorgensen, Mike Springer
132 Copy numbers Small Molecule Copy Numbers Number of Cl ions E. coli 2400000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 2,400,000 (6 mM) Ron Milo, Paul Jorgensen, Mike Springer
133 Copy numbers Small Molecule Copy Numbers Number of Mg ions E. coli 4000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 4,000,000 (10 mM) Ron Milo, Paul Jorgensen, Mike Springer
134 Copy numbers Small Molecule Copy Numbers Number of Fe ions E. coli 7000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 7,000,000 (18 mM) Ron Milo, Paul Jorgensen, Mike Springer
135 Copy numbers Small Molecule Copy Numbers Number of Mn ions E. coli 1700000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1,700,000 (4 mM) Ron Milo, Paul Jorgensen, Mike Springer
136 Copy numbers Small Molecule Copy Numbers Number of Zn ions E. coli 1700000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1,700,000 (4 mM) Ron Milo, Paul Jorgensen, Mike Springer
137 Copy numbers Small Molecule Copy Numbers Number of Mo ions E. coli 1700000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1,700,000 (4 mM) Ron Milo, Paul Jorgensen, Mike Springer
138 Copy numbers Small Molecule Copy Numbers Number of Cu ions E. coli 1700000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1,700,000 (4 mM) Ron Milo, Paul Jorgensen, Mike Springer
139 Copy numbers Small Molecule Copy Numbers Number of PO4 ions E. coli 2000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 2,000,000 (5 mM) Ron Milo, Paul Jorgensen, Mike Springer
140 Copy numbers Small Molecule Copy Numbers Number of glucose/cell E. coli 200,000-400,000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 200,000-400,000 (0.5-1 mM) Ron Milo, Paul Jorgensen, Mike Springer
141 Copy numbers Small Molecule Copy Numbers Number of PEP/cell E. coli 1100000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1,100,000 (2.8 mM) Ron Milo, Paul Jorgensen, Mike Springer
142 Copy numbers Small Molecule Copy Numbers Number of pyruvate/cell E. coli 370000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 370,000 (0.9 mM) Ron Milo, Paul Jorgensen, Mike Springer
143 Copy numbers Small Molecule Copy Numbers Number of gluc-6-PO4/cell E. coli 20000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 20,000 (0.05 mM) Ron Milo, Paul Jorgensen, Mike Springer
144 Copy numbers Small Molecule Copy Numbers Number of ATP/cell E. coli 500,000 - 3,000,000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 500,000 - 3,000,000 (1.3-7.0 mM) Ron Milo, Paul Jorgensen, Mike Springer
145 Copy numbers Small Molecule Copy Numbers Number of ADP/cell E. coli 70000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 70,000 (0.17 mM) Ron Milo, Paul Jorgensen, Mike Springer
146 Copy numbers Small Molecule Copy Numbers Number of NADP/cell E. coli 240000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 240,000 (0.63 mM) Ron Milo, Paul Jorgensen, Mike Springer
147 Copy numbers Small Molecule Copy Numbers Number of NADPH/cell E. coli 220000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 220,000 (0.56 mM) Ron Milo, Paul Jorgensen, Mike Springer
148 Copy numbers Small Molecule Copy Numbers Number of all amino acids/cell E. coli 6000000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 6,000,000 (1.5 mM) Ron Milo, Paul Jorgensen, Mike Springer
149 Copy numbers Small Molecule Copy Numbers Number of free Alanine/cell E. coli 350000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 350,000 (0.8 mM) Ron Milo, Paul Jorgensen, Mike Springer
150 Copy numbers Small Molecule Copy Numbers Number of free Cysteine/cell E. coli 80000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 80,000 (0.2 mM) Ron Milo, Paul Jorgensen, Mike Springer
151 Copy numbers Small Molecule Copy Numbers Number of free Aspartate/cell E. coli 530000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 530,000 (1.34 mM) Ron Milo, Paul Jorgensen, Mike Springer
152 Copy numbers Small Molecule Copy Numbers Number of free Glutamate/cell E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 200,000 (0.5 mM) Ron Milo, Paul Jorgensen, Mike Springer
153 Copy numbers Small Molecule Copy Numbers Number of free Phenylalanine/cell E. coli 170000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 170,000 (0.4 mM) Ron Milo, Paul Jorgensen, Mike Springer
154 Copy numbers Small Molecule Copy Numbers Number of free Glycine/cell E. coli 350000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 350,000 (0.8 mM) Ron Milo, Paul Jorgensen, Mike Springer
155 Copy numbers Small Molecule Copy Numbers Number of free Histidine/cell E. coli 80000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 80,000 (0.2 mM) Ron Milo, Paul Jorgensen, Mike Springer
156 Copy numbers Small Molecule Copy Numbers Number of free Isoleucine/cell E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 200,000 (0.5 mM) Ron Milo, Paul Jorgensen, Mike Springer
157 Copy numbers Small Molecule Copy Numbers Number of free Lysine/cell E. coli 190000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 190,000 (0.46 mM) Ron Milo, Paul Jorgensen, Mike Springer
158 Copy numbers Small Molecule Copy Numbers Number of free Leucine/cell E. coli 300000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 300,000 (0.7 mM) Ron Milo, Paul Jorgensen, Mike Springer
159 Copy numbers Small Molecule Copy Numbers Number of free Methionine/cell E. coli 40000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 40,000 (0.1 mM) Ron Milo, Paul Jorgensen, Mike Springer
160 Copy numbers Small Molecule Copy Numbers Number of free Asparagine/cell E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 200,000 (0.5 mM) Ron Milo, Paul Jorgensen, Mike Springer
161 Copy numbers Small Molecule Copy Numbers Number of free Proline/cell E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 200,000 (0.5 mM) Ron Milo, Paul Jorgensen, Mike Springer
162 Copy numbers Small Molecule Copy Numbers Number of free Glutamine/cell E. coli 200000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 200,000 (0.5 mM) Ron Milo, Paul Jorgensen, Mike Springer
163 Copy numbers Small Molecule Copy Numbers Number of free Arginine/cell E. coli 170000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 170,000 (0.4 mM) Ron Milo, Paul Jorgensen, Mike Springer
164 Copy numbers Small Molecule Copy Numbers Number of free Serine/cell E. coli 300000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 300,000 (0.7 mM) Ron Milo, Paul Jorgensen, Mike Springer
165 Copy numbers Small Molecule Copy Numbers Number of free Threonine/cell E. coli 1400000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 1,400,000 (3.49 mM) Ron Milo, Paul Jorgensen, Mike Springer
166 Copy numbers Small Molecule Copy Numbers Number of free Valine/cell E. coli 240000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 240,000 (0.6 mM) Ron Milo, Paul Jorgensen, Mike Springer
167 Copy numbers Small Molecule Copy Numbers Number of free Tryptophan/cell E. coli 80000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 80,000 (0.2 mM) Ron Milo, Paul Jorgensen, Mike Springer
168 Copy numbers Small Molecule Copy Numbers Number of free Tyrosine/cell E. coli 300000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference 300,000 (0.7 mM) Ron Milo, Paul Jorgensen, Mike Springer
169 Pressure Small Molecule Copy Numbers Osmotic pressure (pushing out) E. coli 75 lb/in2 http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference inner, pressure, osmotic, internal Equivalent to about 5 Atm (50ton/m^2) Ron Milo, Paul Jorgensen, Mike Springer
170 Energetic cost E. coli Metabolism One glucose generates (total) E. coli 36-38 ATP http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
171 Energetic cost E. coli Metabolism Glycolysis yields E. coli 39241 ATP http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
172 Energetic cost E. coli Metabolism Oxidation of pyruvate yields E. coli 6 ATP http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
173 Energetic cost E. coli Metabolism Krebs cycle/e- transport yields E. coli 24 ATP http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
174 Energetic cost E. coli Metabolism Number ATP to make 1 DNA E. coli 72289000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
175 Energetic cost E. coli Metabolism Number ATP to make 1 protein (360 aa) E. coli 1500 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
176 Energetic cost E. coli Metabolism Number ATP to make 1 lipid E. coli 7 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
177 Energetic cost E. coli Metabolism Number ATP to make 1 polysaccharide E. coli 2000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
178 Energetic cost E. coli Metabolism Number ATP to make 1 RNA (1000 nt) E. coli 2000 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
179 Energetic cost E. coli Metabolism Number ATP to make 1 cell E. coli 55*10^9 ATP http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
180 Energetic cost E. coli Metabolism Number Glucose molecules consumed E. coli 1.4*10^6 Unitless http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
181 Growth E. coli Metabolism Cell generation time E. coli 30 minutes http://redpoll.pharmacy.ualberta.ca/CCDB/cgi-bin/STAT_NEW.cgi A list of primary sources is given in the reference Ron Milo, Paul Jorgensen, Mike Springer
182 General statistics DNA Chromosomal DNA weight X. laevis 12 pg Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 A list of primary sources is given in the reference Stage VI oocyte Paul Jorgensen
183 General statistics DNA Nucleolar rDNA weight X. laevis 25 pg Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
184 General statistics DNA Nucleolar rDNA X. laevis 2 x 10^6 rDNA repeats Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
185 General statistics DNA Mitochondrial DNA weight X. laevis 4000 pg Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Igor and Dawid, Dev. Biol 27:504-518 (1972) Egg Paul Jorgensen
186 General statistics DNA Mitochondrial DNA X. laevis 10^8 genomes Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
187 General statistics RNA rRNA X. laevis 5 ug Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
188 General statistics RNA 5S RNA X. laevis 60 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
189 General statistics RNA 5S RNA X. laevis 10^12 RNAs Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
190 General statistics RNA tRNA X. laevis 60 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
191 General statistics RNA tRNA X. laevis 1.5 x 10^12 tRNAs Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
192 General statistics RNA snRNA U1 X. laevis 0.07 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
193 General statistics RNA snRNA U1 X. laevis 8 x 10^8 RNAs Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
194 General statistics RNA polyA+ RNA X. laevis 80 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
195 General statistics RNA polyA+ RNA X. laevis 5 x 10^10 RNAs Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte if 2500bp long on average Paul Jorgensen
196 General statistics RNA ribosomal protein mRNA X. laevis 10 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
197 General statistics RNA ribosomal protein mRNA X. laevis 2 x 10^10 transcripts Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
198 General statistics RNA actin mRNA X. laevis 1 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
199 General statistics RNA actin mRNA X. laevis 5 x 10^8 transcripts Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
200 General statistics RNA Hsp70 mRNA X. laevis 0.004 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
201 General statistics RNA Hsp70 mRNA X. laevis 10^6 transcripts Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
202 General statistics RNA Ribosomes X. laevis 10^12 ribosomes Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
203 General statistics Protein Yolk protein X. laevis 250 ug Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
204 General statistics Protein non-yolk protein X. laevis 25 ug Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
205 General statistics Protein non-yolk protein X. laevis 5 x 10^14 proteins Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte if 30K average Paul Jorgensen
206 General statistics Protein Histones X. laevis 140 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
207 General statistics Protein Histones X. laevis 5 x 10^12 histone proteins Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
208 General statistics Protein Nucleoplasmin X. laevis 250 ng Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
209 General statistics Protein Nucleoplasmin X. laevis 5 x 10^12 nucleoplasmin proteins Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
210 General statistics Protein RNA polymerase I and II X. laevis 10^5 greater than a somatic cell Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
211 General statistics Protein RNA polymerase III X. laevis 5 x 10^5 greater than a somatic cell Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
212 General statistics Metabolism Each dNTP X. laevis 10 - 15 pmol Woodland and Pestell, Biochem J. 127:597-605 (1972) Stage VI oocyte Paul Jorgensen
213 General statistics Metabolism rGTP X. laevis 250 pmol Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
214 General statistics Metabolism Methionine X. laevis 40 pmol Hausen and Riebesell, The Early Development of Xenopus laevis, 1991 Stage VI oocyte Paul Jorgensen
215 General statistics Genome Genome Size Escherichia coli (Bacterium) 4.6*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
216 General statistics Genome Genome Size Sacchromyces cerevisiae (Yeast) 12156678 Base pairs http://www.yeastgenome.org/cache/genomeSnapshot.html Ron Milo
217 General statistics Genome Genome Size Neurospora crassa (Fungus) 39.9*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
218 General statistics Genome Genome Size C. elegans (Nematode) 100*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
219 General statistics Genome Genome Size C. briggsae (Nematode) 104*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
220 General statistics Genome Genome Size Drosophila melanogaster (Fruit fly) 120*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
221 General statistics Genome Genome Size Anapheles gambiae (Mosquito) 280*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
222 General statistics Genome Genome Size Gallus gallus (Chicken) 120*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
223 General statistics Genome Genome Size Fugu rubripes (Pufferfish) 365*10^6 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
224 General statistics Genome Genome Size Danio rario (Zebrafish) 1.7*10^9 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html (?) Ron Milo
225 General statistics Genome Genome Size Mouse 3*10^9 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
226 General statistics Genome Genome Size Xenopus laevis (Frog) 3*10^9 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html ~ Ron Milo
227 General statistics Genome Genome Size Human 3*10^9 Base pairs http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
228 General statistics Genome Number of genes Escherichia coli (Bacterium) 3000 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
229 General statistics Genome Number of genes Yeast 6609 ORF http://www.yeastgenome.org/cache/genomeSnapshot.html Ron Milo
230 General statistics Genome Number of genes Neurospora crassa (Fungus) 10000 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html (Release Apr 2003) Ron Milo
231 General statistics Genome Number of genes C. elegans (Nematode) 20621 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html (Release WS108) Ron Milo
232 General statistics Genome Number of genes C. briggsae (Nematode) 19507 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html (Release Sept 2003) Ron Milo
233 General statistics Genome Number of genes Drosophila melanogaster (Fruit fly) 13647 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html (Release 3.1) Ron Milo
234 General statistics Genome Number of genes Anapheles gambiae (Mosquito) 13600 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
235 General statistics Genome Number of genes Fugu rubripes (Pufferfish) 38000 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
236 General statistics Genome Number of genes Mouse 30000 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
237 General statistics Genome Number of genes Human 31000 Genes http://wormlab.caltech.edu/briggsae/genomeSize.html Ron Milo
238 General statistics Genome Number of tRNA Yeast 299 unitless http://www.yeastgenome.org/cache/genomeSnapshot.html Ron Milo
239 General statistics Genome Number of rRNA Yeast 27 unitless http://www.yeastgenome.org/cache/genomeSnapshot.html Ron Milo
240 Growth Generation time Minimal generation time Vibrio natriegens 9.8 Minutes R. G. Eagon, J. Bacteriol. 83:736-737, 1962 Optimal growth occurred at 37 C in brain heart infusion broth supplemented with 1.5% sea salt. Ron Milo
241 Growth Generation time Minimal generation time Escherichia coli 17 Minutes http://textbookofbacteriology.net/growth.html medium: Glucose-salts Ron Milo
242 Growth Generation time Minimal generation time Bacillus megaterium 25 Minutes http://textbookofbacteriology.net/growth.html medium: Sucrose-salts Ron Milo
243 Growth Generation time Minimal generation time Streptococcus lactis 26 Minutes http://textbookofbacteriology.net/growth.html medium: Milk Ron Milo
244 Growth Generation time Minimal generation time Streptococcus lactis 48 Minutes http://textbookofbacteriology.net/growth.html medium: Lactose broth Ron Milo
245 Growth Generation time Minimal generation time Staphylococcus aureus 27-30 Minutes http://textbookofbacteriology.net/growth.html medium: Heart infusion broth Ron Milo
246 Growth Generation time Minimal generation time Lactobacillus acidophilus 66-87 Minutes http://textbookofbacteriology.net/growth.html medium: Milk Ron Milo
247 Growth Generation time Minimal generation time Rhizobium japonicum 344-461 Minutes http://textbookofbacteriology.net/growth.html medium: Mannitol-salts-yeast extract Ron Milo
248 Growth Generation time Minimal generation time Mycobacterium tuberculosis 792-932 Minutes http://textbookofbacteriology.net/growth.html medium: Synthetic Ron Milo
249 Growth Generation time Minimal generation time Treponema pallidum 1980 Minutes http://textbookofbacteriology.net/growth.html medium: Rabbit testes Ron Milo
250 copy numbers Chemotaxis Number of chemoreceptors (total) E. coli 15000 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html strain RP437 grown in TB medium Tom Shimizu
251 copy numbers Chemotaxis Number of major receptors (Tsr+Tar) E. coli 14000 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
252 copy numbers Chemotaxis Number of minor receptors (Trg+Tap+Aer) E. coli 1000 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
253 copy numbers Chemotaxis Number of kinases (CheA) E. coli 4500 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
254 copy numbers Chemotaxis Number of receptor-kinase couplers (CheW) E. coli 6700 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
255 copy numbers Chemotaxis Number of output response regulators (CheY) E.coli 8200 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
256 copy numbers Chemotaxis Number of phosphatases (CheZ) E. coli 3200 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
257 copy numbers Chemotaxis Number of feedback response regulators (CheB) E. coli 240 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
258 copy numbers Chemotaxis Number of methyltransferases E. coli 140 proteins http://www.pdn.cam.ac.uk/groups/comp-cell/Rates.html Li & Hazelbauer (PNAS, 2004) strain RP437 grown in TB medium Tom Shimizu
259 Rates Chemotaxis Time constant for sub-saturating response E. coli 4 seconds Segall, Block & Berg (PNAS, 1986) Li & Hazelbauer (PNAS, 2004) Tom Shimizu
260 Dynamic range Chemotaxis Dynamic range for gradient sensing of alpha-methylaspartate E.coli 5 orders of magnitude Mesibov, Ordal & Adler (J. Gen. Physiol., 1973) this is minimal estimation, i.e. larger than 5 orders of magnitude Tom Shimizu
261 Biophysical parameters Diffusion rates Diffusion rate of small molecule Generic 50 10^-7*cm^2/sec "Cell movements - from molecules to motility", pp. 6, Dennis Bray, 2nd ed. Garland, 2001 Hille (1992), Berg (1993), Atkins (1994) order of magnitude. ~1msec for a distance of 1 micron Ron Milo
262 Biophysical parameters Diffusion rates Diffusion rate of protein molecule Generic 5 10^-7*cm^2/sec "Cell movements - from molecules to motility", pp. 6, Dennis Bray, 2nd ed. Garland, 2001 Hille (1992), Berg (1993), Atkins (1994) order of magnitude. ~10msec for a distance of 1 micron Ron Milo
263 Biophysical parameters Diffusion rates Diffusion rate of virus particle Generic 0.5 10^-7*cm^2/sec "Cell movements - from molecules to motility", pp. 6, Dennis Bray, 2nd ed. Garland, 2001 Hille (1992), Berg (1993), Atkins (1994) order of magnitude. ~0.1sec for a distance of 1 micron Ron Milo
264 Biophysical parameters Diffusion rates Diffusion rate of bacterial cell Generic 0.05 10^-7*cm^2/sec "Cell movements - from molecules to motility", pp. 6, Dennis Bray, 2nd ed. Garland, 2001 Hille (1992), Berg (1993), Atkins (1994) order of magnitude. ~1sec for a distance of 1 micron Ron Milo
265 Biophysical parameters Diffusion rates Diffusion rate of animal cell Generic 0.005 10^-7*cm^2/sec "Cell movements - from molecules to motility", pp. 6, Dennis Bray, 2nd ed. Garland, 2001 Hille (1992), Berg (1993), Atkins (1994) order of magnitude. ~10sec for a distance of 1 micron Ron Milo
266 Biophysical parameters Diffusion rates Diffusion rate of Pancreatic trypsin inhibitor Bovine 12.9 10^-7*cm^2/sec "Proteins", Creighton 1984 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
267 Biophysical parameters Diffusion rates Diffusion rate of cytochrome c Equine 13 10^-7*cm^2/sec "Proteins", Creighton 1985 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1979 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
268 Biophysical parameters Diffusion rates Diffusion rate of Ribonuclease A Bovine 10.7 10^-7*cm^2/sec "Proteins", Creighton 1986 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1980 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
269 Biophysical parameters Diffusion rates Diffusion rate of Lysozyme Hen 11.3 10^-7*cm^2/sec "Proteins", Creighton 1987 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1981 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
270 Biophysical parameters Diffusion rates Diffusion rate of Myoglobin Sperm whale 11.3 10^-7*cm^2/sec "Proteins", Creighton 1988 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1982 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
271 Biophysical parameters Diffusion rates Diffusion rate of Adenylate kinase Porcine 10.2 10^-7*cm^2/sec "Proteins", Creighton 1989 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1983 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
272 Biophysical parameters Diffusion rates Diffusion rate of Trypsin Bovine 9.3 10^-7*cm^2/sec "Proteins", Creighton 1990 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1984 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
273 Biophysical parameters Diffusion rates Diffusion rate of Bence Jones REI Porcine 10 10^-7*cm^2/sec "Proteins", Creighton 1991 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1985 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
274 Biophysical parameters Diffusion rates Diffusion rate of Chymotrypsinogen Human 9.48 10^-7*cm^2/sec "Proteins", Creighton 1992 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1986 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
275 Biophysical parameters Diffusion rates Diffusion rate of Elastase Bovine 9.5 10^-7*cm^2/sec "Proteins", Creighton 1993 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1987 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
276 Biophysical parameters Diffusion rates Diffusion rate of Subtilisin novo Porcine 9.04 10^-7*cm^2/sec "Proteins", Creighton 1994 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1988 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
277 Biophysical parameters Diffusion rates Diffusion rate of Carbonic anhydrase B. amyloliq. 10.7 10^-7*cm^2/sec "Proteins", Creighton 1995 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1989 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
278 Biophysical parameters Diffusion rates Diffusion rate of Superoxide dismutase Human 8.92 10^-7*cm^2/sec "Proteins", Creighton 1996 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1990 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
279 Biophysical parameters Diffusion rates Diffusion rate of Carboxypeptidase A Bovine 9.2 10^-7*cm^2/sec "Proteins", Creighton 1997 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1991 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
280 Biophysical parameters Diffusion rates Diffusion rate of Phosphoglycerate kinase Bovine 6.38 10^-7*cm^2/sec "Proteins", Creighton 1998 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1992 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
281 Biophysical parameters Diffusion rates Diffusion rate of Concanavalin A Yeast 6.34 10^-7*cm^2/sec "Proteins", Creighton 1999 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1993 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
282 Biophysical parameters Diffusion rates Diffusion rate of Hemoglobin, oxy Equine 6.02 10^-7*cm^2/sec "Proteins", Creighton 2000 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1994 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
283 Biophysical parameters Diffusion rates Diffusion rate of Malate dehydrogenase Porcine 5.76 10^-7*cm^2/sec "Proteins", Creighton 2001 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1995 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
284 Biophysical parameters Diffusion rates Diffusion rate of Alcohol dehydrogenaseh Equine 6.23 10^-7*cm^2/sec "Proteins", Creighton 2002 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1996 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
285 Biophysical parameters Diffusion rates Diffusion rate of Lactate dehydrogenase Dogfish 4.99 10^-7*cm^2/sec "Proteins", Creighton 2003 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1997 Translational diffusion coefficient at 20degC in water, extraploated to zero protein concentration Ron Milo
286 Biophysical parameters Molecular weights Molecular weight of Pancreatic trypsin inhibitor Bovine 6520 Dalton "Proteins", Creighton 2004 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1998 Calculated from covalent structure Ron Milo
287 Biophysical parameters Molecular weights Molecular weight of cytochrome c Equine 12310 Dalton "Proteins", Creighton 2005 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 1999 Calculated from covalent structure Ron Milo
288 Biophysical parameters Molecular weights Molecular weight of Ribonuclease A Bovine 13690 Dalton "Proteins", Creighton 2006 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2000 Calculated from covalent structure Ron Milo
289 Biophysical parameters Molecular weights Molecular weight of Lysozyme Hen 14320 Dalton "Proteins", Creighton 2007 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2001 Calculated from covalent structure Ron Milo
290 Biophysical parameters Molecular weights Molecular weight of Myoglobin Sperm whale 17800 Dalton "Proteins", Creighton 2008 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2002 Calculated from covalent structure Ron Milo
291 Biophysical parameters Molecular weights Molecular weight of Adenylate kinase Porcine 21640 Dalton "Proteins", Creighton 2009 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2003 Calculated from covalent structure Ron Milo
292 Biophysical parameters Molecular weights Molecular weight of Trypsin Bovine 23200 Dalton "Proteins", Creighton 2010 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2004 Calculated from covalent structure Ron Milo
293 Biophysical parameters Molecular weights Molecular weight of Bence Jones REI Porcine 23500 Dalton "Proteins", Creighton 2011 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2005 Calculated from covalent structure Ron Milo
294 Biophysical parameters Molecular weights Molecular weight of Chymotrypsinogen Human 25670 Dalton "Proteins", Creighton 2012 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2006 Calculated from covalent structure Ron Milo
295 Biophysical parameters Molecular weights Molecular weight of Elastase Bovine 25900 Dalton "Proteins", Creighton 2013 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2007 Calculated from covalent structure Ron Milo
296 Biophysical parameters Molecular weights Molecular weight of Subtilisin novo Porcine 27530 Dalton "Proteins", Creighton 2014 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2008 Calculated from covalent structure Ron Milo
297 Biophysical parameters Molecular weights Molecular weight of Carbonic anhydrase B. amyloliq. 28800 Dalton "Proteins", Creighton 2015 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2009 Calculated from covalent structure Ron Milo
298 Biophysical parameters Molecular weights Molecular weight of Superoxide dismutase Human 33900 Dalton "Proteins", Creighton 2016 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2010 Calculated from covalent structure Ron Milo
299 Biophysical parameters Molecular weights Molecular weight of Carboxypeptidase A Bovine 34500 Dalton "Proteins", Creighton 2017 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2011 Calculated from covalent structure Ron Milo
300 Biophysical parameters Molecular weights Molecular weight of Phosphoglycerate kinase Bovine 45800 Dalton "Proteins", Creighton 2018 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2012 Calculated from covalent structure Ron Milo
301 Biophysical parameters Molecular weights Molecular weight of Concanavalin A Yeast 51260 Dalton "Proteins", Creighton 2019 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2013 Calculated from covalent structure Ron Milo
302 Biophysical parameters Molecular weights Molecular weight of Hemoglobin, oxy Equine 64610 Dalton "Proteins", Creighton 2020 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2014 Calculated from covalent structure Ron Milo
303 Biophysical parameters Molecular weights Molecular weight of Malate dehydrogenase Porcine 74900 Dalton "Proteins", Creighton 2021 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2015 Calculated from covalent structure Ron Milo
304 Biophysical parameters Molecular weights Molecular weight of Alcohol dehydrogenaseh Equine 79870 Dalton "Proteins", Creighton 2022 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2016 Calculated from covalent structure Ron Milo
305 Biophysical parameters Molecular weights Molecular weight of Lactate dehydrogenase Dogfish 146200 Dalton "Proteins", Creighton 2023 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2017 Calculated from covalent structure Ron Milo
306 DNA Mutation Rates Mutation rate per base pair per replication Bacteriophage M13 7.2 x 10-7 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 1998 Squire & Himmel, Arch. Biochem. Biophys. 196:165-177, 2018 Ron Milo
307 DNA Mutation Rates Mutation rate per base pair per replication Bacteriophage {lambda} 7.7 x 10-8 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 1999 Ron Milo
308 DNA Mutation Rates Mutation rate per base pair per replication Bacteriophages T2 and T4 2.4 x 10-8 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2000 Ron Milo
309 DNA Mutation Rates Mutation rate per base pair per replication Escherichia coli 5.4 x 10-10 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2001 Ron Milo
310 DNA Mutation Rates Mutation rate per base pair per replication Saccharomyces cerevisiae 2.2 x 10-10 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 1998 Ron Milo
311 DNA Mutation Rates Mutation rate per base pair per replication Neurospora crassa 7.2 x 10-11 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 1999 Ron Milo
312 DNA Mutation Rates Mutation rate per base pair per replication C. elegans 2.3 x 10-10 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 1998 Ron Milo
313 DNA Mutation Rates Mutation rate per base pair per replication Drosophila 3.4 x 10-10 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 1999 Ron Milo
314 DNA Mutation Rates Mutation rate per base pair per replication Mouse 1.8 x 10-10 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2000 Ron Milo
315 DNA Mutation Rates Mutation rate per base pair per replication Human 5.0 x 10-11 mutation/bp/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2001 Ron Milo
316 DNA Mutation Rates Mutation rate per genome per replication Bacteriophage M13 0.0046 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2001 Notice that this is per gemone replication not per sexual generation Ron Milo
317 DNA Mutation Rates Mutation rate per genome per replication Bacteriophage {lambda} 0.0038 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2002 Notice that this is per gemone replication not per sexual generation Ron Milo
318 DNA Mutation Rates Mutation rate per genome per replication Bacteriophages T2 and T4 0.004 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2003 Notice that this is per gemone replication not per sexual generation Ron Milo
319 DNA Mutation Rates Mutation rate per genome per replication Escherichia coli 0.0025 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2004 Ron Milo
320 DNA Mutation Rates Mutation rate per genome per replication Saccharomyces cerevisiae 0.0027 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2005 Ron Milo
321 DNA Mutation Rates Mutation rate per genome per replication Neurospora crassa 0.003 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2006 Notice that this is per gemone replication not per sexual generation Ron Milo
322 DNA Mutation Rates Mutation rate per genome per replication C. elegans 0.018 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2007 Notice that this is per gemone replication not per sexual generation Ron Milo
323 DNA Mutation Rates Mutation rate per genome per replication Drosophila 0.058 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2008 Notice that this is per gemone replication not per sexual generation Ron Milo
324 DNA Mutation Rates Mutation rate per genome per replication Mouse 0.49 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2009 Notice that this is per gemone replication not per sexual generation Ron Milo
325 DNA Mutation Rates Mutation rate per genome per replication Human 0.16 mutation/genome/replication Drake et. al., Genetics, Vol. 148, 1667-1686, April 2010 Notice that this is per gemone replication not per sexual generation Ron Milo
326 Growth Growth Generation time Chlamydomonas reinhardtii 5 Hours http://www.yale.edu/rosenbaum/green_yeast.html Ron Milo
327 DNA Genome Number of chromosomes/cell Chlamydomonas reinhardtii 17 Unitless http://www.yale.edu/rosenbaum/green_yeast.html Ron Milo
328 DNA Genome Genome Size Chlamydomonas reinhardtii 120*10^6 Base pairs http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Ron Milo
329 Composition Water percentage of the total wet weight of cells bacteria 70 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
330 Composition Water percentage of the total wet weight of cells chicken heart fibroblasts 77 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
331 Composition Water percentage of the total wet weight of cells rat kidney cells 74 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
332 Composition Water percentage of the total wet weight of cells HeLa cells 70 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
333 Composition Water percentage of the total wet weight of cells axon 87 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
334 Composition Protein Percentage by Weight bacteria 20-32 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
335 Composition Protein Percentage by Weight muscle cells 23 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
336 Composition Protein Percentage by Weight red blood cells 35 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
337 Composition Protein Percentage by Weight mammalian tissue cells 17-26 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
338 Composition Protein Percentage by Weight squid axoplasm 5 Percent "Cell movements - from molecules to motility", pp. 303, Dennis Bray, 2nd ed. Garland, 2001 not given Ron Milo
339 Sizes Volume median cell volume Yeast 42 micron^3 http://yeastpheromonemodel.org/wiki/Cell_volume Jorgensen et al. 2002 PMID 120894449 The median volume of a haploid yeast cell in exponential phase growing in YPD at 30°C Ron Milo
340 Sizes Volume median cell volume Yeast 37 micron^3 http://yeastpheromonemodel.org/wiki/Cell_volume Tyson et al. 1979 PMID 374379 The mean volume of a haploid yeast cell in exponential phase growing in YPD at 30°C Ron Milo
341 Transcription Ribosome Percent of total transcription devoted to ribosomal RNA Yeast 60 Percent The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Ron Milo
342 Transcription RNA to DNA ratio Yeast 50 Unitless The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Ron Milo
343 Transcription Percent of total RNA that is ribosomal RNA Yeast 80 Percent The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Ron Milo
344 Transcription Percent of total RNA that is tRNA Yeast 15 Percent The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Ron Milo
345 Transcription Percent of total RNA that is ribosomal mRNA Yeast 5 Percent The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Ron Milo
346 Complexes copy number Number of ribosomes Yeast 200000 Unitless The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Based on comparison of the size of the genome (1.4 3 107 bp) with the RNA in a ribosome (5469 nucleotides), and using ratio of DNA to rRNA Ron Milo
347 Growth Generation time Yeast 100 minutes The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Ron Milo
348 mRNA copy number Number of mRNAs in cell Yeast 15000 Unitless The economics of ribosome biosynthesis in yeast, JR Warner - Trends Biochem. Sci, 1999 Holstege, F. C. P. et al. (1998) Cell 95, 717�$-1òó728 Ron Milo
349 Weight genome Weight of DNA base pair generic 665 Dalton http://www.roche-applied-science.com/PROD_INF/MANUALS/napi_man/pdf/chapter9/page_212-215.pdf Ausubel et al., 1988 Notice this is a base PAIR Itai Yanai
350 Weight genome Weight of single stranded DNA base generic 325 Dalton http://www.roche-applied-science.com/PROD_INF/MANUALS/napi_man/pdf/chapter9/page_212-215.pdf Ausubel et al., 1988 Itai Yanai
351 Weight genome Weight of single stranded RNA base generic 340 Dalton http://www.roche-applied-science.com/PROD_INF/MANUALS/napi_man/pdf/chapter9/page_212-215.pdf Ausubel et al., 1988 Itai Yanai
352 Weight genome Conversion from weight to bp generic 978 Mbp/pgram Gregory, T.R. (2007). Animal Genome Size Database. http://www.genomesize.com Dolezel et al., Cytometry 51A: 127-128, 2003 Ron Milo
353 Thermosensitivity TRP channels Q10 (24-36°C) of TRPV4 mouse 19.1 Unitless Watanabe et al., J. Biol. Chem. 2002 In HEK293 Cell Daniel Ramot
354 Thermosensitivity TRP channels TRPV1 Q10 (41�$-1òó50°C) rat 27 Unitless Liu, Hui, & Qin, Biophys J. 2003 Single-channel activity in Xenopus laevis oocytes Daniel Ramot
355 Thermosensitivity Sensory neurons Q10 (47�$-1òó51°C) of heat activated current in DRG neurons rat 17.8 Unitless Vyklický et al., J. Physiol 1999 Cultured neurons Daniel Ramot
356 Thermosensitivity TRP channels TRPV3 Q10 mouse 6.62 Unitless Peier et al., Science 2002 In CHO cells Daniel Ramot
357 Thermosensitivity K+ Channels Q10 (5�$-1òó20°C) of Shaker K+ channel peak amplitude Drosophila 1.51 Unitless Nobile et al., Exp Brain Res, 1997 In Xenopus laevis oocytes - cut open oocyte method Daniel Ramot
358 Thermosensitivity K+ Channels Q10 (5�$-1òó20°C) of Shaker K+ channel activation time constant Drosophila 3.14 Unitless Nobile et al., Exp Brain Res, 1997 In Xenopus laevis oocytes - cut open oocyte method Daniel Ramot
359 Thermosensitivity K+ Channels Q10 (5�$-1òó20°C) of Shaker K+ channel inactivation time constant Drosophila 7.2 Unitless Nobile et al., Exp Brain Res, 1997 In Xenopus laevis oocytes - cut open oocyte method Daniel Ramot
360 Thermosensitivity K+ Channels Q10 (5�$-1òó20°C) of Shaker K+ channel ratio b/w steady-state & peak current Drosophila 2.95 Unitless Nobile et al., Exp Brain Res, 1997 In Xenopus laevis oocytes - cut open oocyte method Daniel Ramot
361 Thermosensitivity TRP channels TRPV1 Q10 20.6 Unitless Welch et al., PNAS 2000 Daniel Ramot
362 Thermosensitivity TRP channels TRPV1 Q10 25.6 Unitless Vlachová et al., J. Neurosci. 2003 Daniel Ramot
363 Copy numbers Small Molecule Copy Numbers Number of Zn ions in YPD yeast 8e7 Eide et al. Genome Biology 2005 Mike Springer
364 Copy numbers Small Molecule Copy Numbers Number of Se ions in YPD yeast 6e7 Eide et al. Genome Biology 2005 Mike Springer
365 Copy numbers Small Molecule Copy Numbers Number of S ions in YPD yeast 5e8 Eide et al. Genome Biology 2005 Mike Springer
366 Copy numbers Small Molecule Copy Numbers Number of P ions in YPD yeast 5e9 Eide et al. Genome Biology 2005 Mike Springer
367 Copy numbers Small Molecule Copy Numbers Number of Ni ions in YPD yeast 2e7 Eide et al. Genome Biology 2005 Mike Springer
368 Copy numbers Small Molecule Copy Numbers Number of Na ions in YPD yeast 2e8 Eide et al. Genome Biology 2005 Mike Springer
369 Copy numbers Small Molecule Copy Numbers Number of Mn ions in YPD yeast 5e5 Eide et al. Genome Biology 2005 Mike Springer
370 Sizes Volumes Nuclear volume (average) S. cerevisiae 2.9 um3 Jorgensen et al. MBC 2007 Morphometry SD 2% glucose medium, wild-type haploid cells Paul Jorgensen
371 Sizes Volumes Nuclear:cell volume ratio S. cerevisiae 0.07 Unitless Jorgensen et al. MBC 2007 SD 2% glucose medium, wild-type haploid cells Paul Jorgensen
372 Sizes Volumes Cell volume S. cerevisiae 42 um3 Jorgensen et al. MBC 2007 Coulter counter 17 SD 2% glucose medium, wild-type haploid cells Paul Jorgensen
373 General statistics Proliferation Number of cell divisions in an average human lifespan H. sapiens 10e17 Cell divisions Weinberg, R. The Biology of Cancer 2007 Paul Jorgensen
374 Sizes Dimensions Cell diameter S. cerevisiae 5 um Roskams and Rodgers, LabRef Paul Jorgensen
375 Sizes Volumes Cell volume S. cerevisiae 66 um3 Roskams and Rodgers, LabRef Paul Jorgensen
376 Sizes Dimensions Cell dimensions S. pombe 2 x 7 um Roskams and Rodgers, LabRef Paul Jorgensen
377 Sizes Volumes Cell volume S. pombe 22 um3 Roskams and Rodgers, LabRef Paul Jorgensen
378 Sizes Dimensions Cell diameter Mammalian cell 10 - 20 um Roskams and Rodgers, LabRef Paul Jorgensen
379 Sizes Volumes Cell volume Mammalian cell 500 - 4000 um3 Roskams and Rodgers, LabRef Paul Jorgensen
380 Sizes Dimensions Cell dimensions E. coli 1 x 3 um Roskams and Rodgers, LabRef Paul Jorgensen
381 Sizes Volumes Cell volume E. coli 2 um3 Roskams and Rodgers, LabRef Paul Jorgensen
382 Sizes Organelle size Mitochonrdia dimensions Mammalian cell 1 um Roskams and Rodgers, LabRef Paul Jorgensen
383 Sizes Organelle size Mitochondria volume Mammalian cell 0.5 um3 Roskams and Rodgers, LabRef Paul Jorgensen
384 Sizes Organelle size Nuclear diameter Mammalian cell 5 - 10 um Roskams and Rodgers, LabRef Paul Jorgensen
385 Sizes Organelle size Nuclear volume Mammalian cell 66 - 500 um3 Roskams and Rodgers, LabRef Paul Jorgensen
386 Sizes Organelle size Chloroplast dimensions Plant cell 1 x 4 um Roskams and Rodgers, LabRef Paul Jorgensen
387 Sizes Organelle size Chloroplast volume Plant cell 3 um3 Roskams and Rodgers, LabRef Paul Jorgensen
388 Sizes Virus diameter, head only Bacteriophase Lambda 6.6e-5 um3 Roskams and Rodgers, LabRef Paul Jorgensen
389 Sizes Virus diameter, head only Bacteriophase Lambda 50 nm Roskams and Rodgers, LabRef Paul Jorgensen
390 Sizes Protein size Ribosome diameter ? 30 nm Roskams and Rodgers, LabRef Paul Jorgensen
391 Sizes Protein size Ribosome volume ? 1.4e-5 um3 Roskams and Rodgers, LabRef Paul Jorgensen
392 Sizes Protein size Globular protein diameter ? 5 nm Roskams and Rodgers, LabRef Paul Jorgensen
393 Sizes Protein size Globular protein volume ? 6.6e-8 um3 Roskams and Rodgers, LabRef Paul Jorgensen
394 Transporters Rates Water flow through aquaporin 1 channel ? 5*10^8 molecules/second Nelson and Cox, "Lehninger - Principles of biochemistry", 3rd ed. p.410 Ron Milo
395 Photosynthesis Sun Flux of photons generic 4*10^21 Photons/m^2/sec Design and engineering of photosynthetic light-harvesting and electron transfer using length, time, and energy scales. Noy D, Moser CC, Dutton PL. PMID: 16457774 Intergration at sea level, based on reference solar irradiance 1.5 air masses, integrated over the whole spectrum Ron Milo
396 Photosynthesis Sun Max Photosynthetic photon flux generic 2000 micromol/m^2/sec Nobel, P. S. "Plant Physiology", 3rd ed. pp.243 in the range 400-700nm on a horizontal plane Ron Milo
397 Photosynthesis Sun Mean Photosynthetic photon flux generic 800 micromol/m^2/sec Nobel, P. S. "Plant Physiology", 3rd ed. pp.245 in the range 400-700nm averaged on daytime over the earth's surface on clear days Ron Milo
398 Photosynthesis concentrations Chlorophyll concentration chloroplast 30 mol/m^3 Nobel, P. S. "Plant Physiology", 3rd ed. pp.243 average Ron Milo
399 Photosynthesis leaves Leaf area index Biosphere 4.3 micromol/m^2/sec Nobel, P. S. "Plant Physiology", 3rd ed. pp.245 Total area of all leaves divided by the total land area where vegetation occurs Ron Milo
400 Photosynthesis Cross section Effective cross section of chlorophyll for useful photons generic 0.09 Angstrom^2 Design and engineering of photosynthetic light-harvesting and electron transfer using length, time, and energy scales. Noy D, Moser CC, Dutton PL. PMID: 16457774 Ron Milo
401 Photosynthesis Absorption Maximal absorption rate under sun illumination of chlorophyll pigment generic 4 1/sec Design and engineering of photosynthetic light-harvesting and electron transfer using length, time, and energy scales. Noy D, Moser CC, Dutton PL. PMID: 16457774 Ron Milo
402 Photosynthesis Rates Catalysis rates of photosystem units generic 10^2-10^4 1/sec Design and engineering of photosynthetic light-harvesting and electron transfer using length, time, and energy scales. Noy D, Moser CC, Dutton PL. PMID: 16457774 Ron Milo
403 Photosynthesis Rates Catalysis rates of photosystem units generic 200 1/sec Nobel, P. S. "Plant Physiology", 3rd ed. pp.243 Ron Milo
404 Photosynthesis copy numbers number of chlorophyll pigments in PSI Synechococcus elongatus 96 unitless Three-dimensional structure of cyanobacterial photosystem I at 2.5 A resolution.Nature. 2001 Jun 21;411(6840):909-17.PMID: 11418848 Ron Milo
405 Photosynthesis copy numbers number of chlorophyll per reaction center plants 100-700 unitless Nobel, P. S. "Plant Physiology", 3rd ed. pp.245 depending on illumination level Ron Milo
406 Photosynthesis copy numbers number of bacteriochlorophylls per reaction center bacteria 40-100 unitless Nobel, P. S. "Plant Physiology", 3rd ed. pp.245 depending on illumination level Ron Milo
407 DNA damage Rates number of depurination events Mammalian cell 10000 bases depurinated per cell per day R. Weinberg, The Biology of Cancer Paul Jorgensen
408 DNA damage Rates number of depyrimidination events Mammalian cell 500 bases depyrimidinated per cell per day R. Weinberg, The Biology of Cancer Paul Jorgensen
409 DNA damage Rates number of DNA damage events caused by oxidative damage H. sapiens cell 10e3 bases damaged per cell per day R. Weinberg, The Biology of Cancer Paul Jorgensen
410 DNA damage Rates number of DNA damage events caused by oxidative damage Rat cell 10e4 bases damaged per cell per day R. Weinberg, The Biology of Cancer Paul Jorgensen
411 Proteins Diffusion rate GFP diffusion rate in cytoplasm E. Coli 7.7 ± 2.5 µm^2/s Elowitz, M.B. et al. (1999) Protein Mobility in the Cytoplasm of E. coli, J. Bacteriol 181, 197-203. Elowitz, M.B. et al. (1999) Protein Mobility in the Cytoplasm of E. coli, J. Bacteriol 181, 197-203. FRAP and photoactivation Ron Milo
412 Proteins Diffusion rate GFP diffusion rate in water Water 87 µm^2/s Elowitz, M.B. et al. (1999) Protein Mobility in the Cytoplasm of E. coli, J. Bacteriol 181, 197-203. Swaminathan, R., C. P. Hoang, and A. S. Verkman. 1997. Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion. Biophys. J. 72:1900-1907; Terry, B. R., E. K. Matthews, and J. Haseloff. 1995. Molecular characterisation of recombinant green fluorescent protein by fluorescence correlation microscopy. Biochem. Biophys. Res. Commun. 217:21-27 Ron Milo
413 Proteins Diffusion rate GFP diffusion rate in cytoplasm Eukaryotic 27 µm^2/s Elowitz, M.B. et al. (1999) Protein Mobility in the Cytoplasm of E. coli, J. Bacteriol 181, 197-203. Swaminathan, R., C. P. Hoang, and A. S. Verkman. 1997. Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion. Biophys. J. 72:1900-1907 Ron Milo
414 Proteins Diffusion rate GFP diffusion rate in mitochondria Mitochondria 20-30 µm^2/s Elowitz, M.B. et al. (1999) Protein Mobility in the Cytoplasm of E. coli, J. Bacteriol 181, 197-203. Partikian, A., B. Olveczky, R. Swaminathan, Y. Li, and A. S. Verkman. 1998. Rapid diffusion of green fluorescent protein in the mitochondrial matrix. J. Cell Biol. 140:821-829 Ron Milo
415 Sizes Dimensions Cell length at division S. pombe 13.5 um Das et al. (2007) MBC 18:2090-2101. Morphometry 1.3 Paul Jorgensen
416 Biosphere Photosynthesis Global primary productivity - [carbon] Biosphere 10^14 kg Nobel, P. S. "Plant Physiology", 3rd ed. pp.219 Ron Milo
417 Biosphere Atmosphere content Total CO2 Atmosphere 8*10^14 kg Nobel, P. S. "Plant Physiology", 3rd ed. pp.220 Ron Milo
418 Biosphere lakes and oceans Total CO2 Biosphere 400*10^14 kg Nobel, P. S. "Plant Physiology", 3rd ed. pp.220 Ron Milo
419 Biosphere Photosynthesis Time for O2 replenishment by photosynthesis Atmosphere 2000 years Nobel, P. S. "Plant Physiology", 3rd ed. pp.220 Ron Milo
420 Copy number p53 human 15 ± 6 x 10^5 unitless Ma et al., PNAS (2005) 102:14266 Measured by ELISA, concentration ranges from 0.06 to 0.5microM depending on cell line MCF7 breast cancer cell line Alex Loewer
421 DNA DNA damage DNA double strand breaks induced by ionizing radiation [DSB per Gray per cell] human 36 unitless Rothkamm et al.,