BME100 f2015:Group16 1030amL2

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Lab Number 2: Using Statistics to measure and analyze data

Results for effect of drug on RATS:


Results of drug on HUMANS
' ' ' '
Dosage Average Standard Deviation Standard Error
0mg 9.24 2.225551617 0.995296941
10mg 11.112 7.402885924 3.310671
Dosage Average Standard Deviation Standard Error
0 mg 3.834 1.444854 0.456903
5 mg 8.932 1.512136 0.478179
10 mg 61.622 28.56551 9.033208
15 mg 657.941 202.0154 63.88289

Effect of Inflammotin on HUMAN Subjects. BME494 Group16 HumanGraph.jpg

Effect of Inflammotin on RAT Subjects. BME494 Group16 Rat Graph.jpg


Single Factor ANOVA Test for HUMAN Subjects

SUMMARY ' ' ' '
Groups Count Sum Average Variance
0 mg 10 38.34 3.834 2.31956
5 mg 10 89.32 8.932 2.540617778
10 mg 10 616.22 61.622 906.6538844
15 mg 10 6579.41 657.941 45344.71112


ANOVA ' ' ' ' ' '
Source of Variation SS df MS F P-value F crit
Between Groups 3027016.695 3 1009005.565 87.25360195 1.40E-16 2.866265551
Within Groups 416306.0267 36 11564.0563
Total 3443322.721 39

Post HOC T-Test for Human Subjects

Summary: The study and experiments show that as as the amount of LPS was increased in both study subjects, the inflammation levels also increased. In regards to the Rat experimental group, as the dosage was increased from 0 mg to 10 mg, the average inflammation levels in all of the subjects also increased (from an average of 9.24 pg/ml to 11.112 pg/ml). For the human test subject counterparts, similar results concurred with the data received from the rats. As the dosage was slowly increased in humans, from 0 mg to 5 mg to 10 mg and finally to 15 mg, the inflammation levels increased exponentially. Also, our one factor ANOVA test and unpaired t test came up with a value greater than 95%, which means that the data is statistically significant in both studies. Overall, a positive correlation and possible causation of LPS being positively correlated with Inflammation levels in both humans and rats is noticed.
Post-hoc Tests t-test value Corrected p-value to achieve significance Significant?
0mg vs. 5mg 8.59631E-07 0.0167 Yes
0mg vs. 10mg 9.94377E-06 0.0167 Yes
0mg vs. 15mg 1.39436E-08 0.0167 Yes
5mg vs. 10mg 3.01859E-05 0.0167 Yes
5mg vs.15mg 1.57101E-08 0.0167 Yes
10mg vs. 15mg 6.4824E-08 0.0167 Yes