This is the OWW entry page for the Alpha Project (improve these pages with impunity)
The static web gateway to the Alpha Project is online here. From this page... the overall goal of the Alpha Project is to gain the ability to predict the quantitative behavior of a eukaryotic regulatory network in individual cells over time and in response to defined perturbations. The project consists of combined experimental and computational work on a well-studied eukaryotic regulatory system, the G-protein receptor-coupled signal transduction pathway that governs the response of haploid MATa S. cerevisiae to the mating pheromone, a factor. This signal transduction pathway is prototypical of similar regulatory networks that govern responses to extracellular stimuli in higher eukaryotes.
The Alpha Project is currently funded by a grant from the NIH National Human Genome Research Institute. Alpha Project investigators are based at the Molecular Sciences Institute, Caltech, MIT, and Pacific Northwest National Laboratory.