User:Omar F. Khan

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Omar F. Khan

Omar F. Khan

Hi, my name is Omar F. Khan, and I'm currently at the Massachusetts Institute of Technology in Professor Robert Langer's lab within the David H. Koch Institute for Integrative Cancer Research. I did my PhD at the University of Toronto under the supervision of Professor Michael V. Sefton. I learned about OpenWetWare from Professor Axel Guenther, and I've joined because I fabricate microfluidic devices. You can email me through OpenWetWare. I am a serving member of the Toronto Microfluidic Foundry's Process Technology Committee.


Postdoctoral Associate, Langer Lab, Massachusetts Institute of Technology


Ph.D., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2010

M.A.Sc., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2006

B.A.Sc.(Honors), Chemical Engineering, University of Toronto, 2004

Publications and Communications

Khan, O.F. and Sefton, M.V. Endothelialized biomaterials for tissue engineering applications in vivo. Trends in Biotechnology (Accepted)

Khan, O.F. and Sefton, M.V. Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications. Journal of Biomaterial Science, DOI: 10.1163/092050610X540693

Chamberlain, M.D., Butler, M.J., Ciucurel, E.C., Fitzpatrick, L.E., Khan, O.F., Leung, B.M., Lo, C., Patel, R., Velchinskaya, A., Voice, D.N. and Sefton, M.V. Fabrication of Micro-Tissues using Modules of Collagen Gel Containing Cells. Journal of Visualized Experiments, DOI: 10.3791/2177

Khan, O.F. and Sefton, M.V. Endothelial Cell Behaviour within a Microfluidic Mimic of the Flow Channels of a Modular Tissue Engineered Construct. Biomedical Microdevices, DOI 10.1007/s10544-010-9472-8, Epub ahead of print Sep 15 2010

Khan, O.F. and Sefton, M.V. Perfusion and Characterization of an Endothelial Cell-Seeded Modular Tissue Engineered Construct Formed in a Microfluidic Remodeling Chamber. Biomaterials, 2010 Nov;31(32):8254-61

Khan, O.F., Jean-Francois, J. and Sefton, M.V. MMP Levels in the Response to Degradable Implants in the Presence of a Hydroxamate-Based Matrix Metalloproteinase Sequestering Biomaterial In Vivo. Journal of Biomedical Materials Research, Part A, 2010 Jun 15;93(4):1368-79.

Sosnik A., Khan O.F., Butler M, Sefton M.V.: Poloxamine hydrogels: From non-cell adhesive substrates to matrices with improved cytocompatibility for Tissue Engineering applications. In Barbucci, R. (Ed.), Hydrogels: Biological Properties and Applications. Springer; 2009.

Khan, O.F., Chamberlain, M.D. and Sefton, M.V. “Modular Tissue Containing Endothelial Cells and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber.” Tissue Engineering and Regenerative Medicine International Society (TERMIS)-European Union Chapter Meeting, Galway, Ireland, June 13-17, 2010. Oral Presentation

Khan, O.F., Leung, B.M. and Sefton, M.V. “Modular Cardiac Tissue Containing Endothelial and Cardiomyocyte Cells formed in a Microfluidic Perfusion Chamber,” Ontario-on-a-Chip, Toronto, ON., Canada, May 20-21, 2010. Oral Presentation

Khan, O.F. and Sefton, M.V. “Collagen/Poloxamine Microfluidic Flow Circuits to Characterize Surface-Attached Endothelial Cells Under Flow.” 8th World Biomaterials Congress, Amsterdam, The Netherlands, May 28-June 1, 2008. Oral Presentation

Khan, O.F. and Sefton, M.V. “In Vivo Use of a Matrix Metalloproteinase-Sequestering Biomaterial to Alter the Inflammatory Response,” Regenerate World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, Pennsylvania, USA, April 23-27, 2006. Poster Presentation

Khan, O.F. and Sefton, M.V. “In Vivo Alteration of the Foreign Body Response Using a Matrix Metalloproteinase-Sequestering Biomaterial,” Challenges in Regenerative Medicine (ChaRM), Toronto, Ontario, Canada, October 20-21, 2005. Poster Presentation

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