Difference between revisions of "User:Marie-Eve Val"

From OpenWetWare
Jump to: navigation, search
(Undo revision 576894 by Marie-Eve Val (Talk))
Line 26: Line 26:
 
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
 
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
 
<biblio>
 
<biblio>
#Paper1 pmid=22253612  
+
#Genome_Engineering_in_Vibrio_cholerae_2012 pmid=22253612  
 
// Genome Engineering in Vibrio cholerae: A Feasible Approach to Address Biological Issues.
 
// Genome Engineering in Vibrio cholerae: A Feasible Approach to Address Biological Issues.
 
#Paper2 pmid=20133778  
 
#Paper2 pmid=20133778  
Line 38: Line 38:
  
 
</biblio>
 
</biblio>
 
+
<biblio>
 +
#Synthetic-Integron-2010 pmid=20534632
 +
#attC-2010 pmid=19730680
 +
#Weak-Root-2009 pmid=19179528
 +
#iGEM-Paris-2007 pmid=18466734
 +
</biblio>
 
==Useful links==
 
==Useful links==
 
*[[OpenWetWare:Welcome|Introductory tutorial]]
 
*[[OpenWetWare:Welcome|Introductory tutorial]]
 
*[[Help|OpenWetWare help pages]]
 
*[[Help|OpenWetWare help pages]]

Revision as of 04:10, 19 January 2012

Marie-Eve.jpg
Vibrio cholerae
site-specific recombination-based engineering tool to massively reorganize V. cholerae's genome
Genome rearrangement events occuring within a single colony

Marie-Eve VAL
INSTITUT PASTEUR
Unité "Plasticité du Génome Bactérien"
Département Génomes et Génétique
CNRS URA2171
25 rue du Dr. Roux
75724 PARIS cedex 15
FRANCE
Email me through OpenWetWare

Research interests

I am a post-doctoral research fellow in Didier Mazel's lab at the Institut Pasteur of Paris. I have a great interest in bacterial genome structuration, organization and maintenance ... and a special interest in multipartite genomes. Owing to its bi-chromosomal genome architecture and its importance in public health, Vibrio cholerae, the causative agent of cholera, has become a preferred model to study bacteria with multipartite genomes. My approach is to drastically alter V. cholerae’s genome structure to gain more insight into multipartite genomes. To do so, I developed a site-specific recombination-based engineering tool, which provides us with a powerful means to massively reorganize in principle any prokaryotic genome. The laboratory of Didier Mazel was an ideal place to initiate such a project since they have developed a large set of genetic tools to work in the vibrios and Didier Mazel has substantial knowledge and experience in site-specific recombination, bacterial genetics and genome analysis.

Education

Professional Training

Publications

  1. Val ME, Skovgaard O, Ducos-Galand M, Bland MJ, and Mazel D. Genome engineering in Vibrio cholerae: a feasible approach to address biological issues. PLoS Genet. 2012 Jan;8(1):e1002472. DOI:10.1371/journal.pgen.1002472 | PubMed ID:22253612 | HubMed [Genome_Engineering_in_Vibrio_cholerae_2012]
    Genome Engineering in Vibrio cholerae: A Feasible Approach to Address Biological Issues.
  2. Das B, Bischerour J, Val ME, and Barre FX. Molecular keys of the tropism of integration of the cholera toxin phage. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4377-82. DOI:10.1073/pnas.0910212107 | PubMed ID:20133778 | HubMed [Paper2]
    Molecular keys of the tropism of integration of the cholera toxin phage.
  3. Génolevures Consortium., Souciet JL, Dujon B, Gaillardin C, Johnston M, Baret PV, Cliften P, Sherman DJ, Weissenbach J, Westhof E, Wincker P, Jubin C, Poulain J, Barbe V, Ségurens B, Artiguenave F, Anthouard V, Vacherie B, Val ME, Fulton RS, Minx P, Wilson R, Durrens P, Jean G, Marck C, Martin T, Nikolski M, Rolland T, Seret ML, Casarégola S, Despons L, Fairhead C, Fischer G, Lafontaine I, Leh V, Lemaire M, de Montigny J, Neuvéglise C, Thierry A, Blanc-Lenfle I, Bleykasten C, Diffels J, Fritsch E, Frangeul L, Goëffon A, Jauniaux N, Kachouri-Lafond R, Payen C, Potier S, Pribylova L, Ozanne C, Richard GF, Sacerdot C, Straub ML, and Talla E. Comparative genomics of protoploid Saccharomycetaceae. Genome Res. 2009 Oct;19(10):1696-709. DOI:10.1101/gr.091546.109 | PubMed ID:19525356 | HubMed [Paper3]
    Comparative genomics of protoploid Saccharomycetaceae.
  4. Val ME, Kennedy SP, El Karoui M, Bonné L, Chevalier F, and Barre FX. FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae. PLoS Genet. 2008 Sep 26;4(9):e1000201. DOI:10.1371/journal.pgen.1000201 | PubMed ID:18818731 | HubMed [Paper4]
    FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae.
  5. Val ME, Bouvier M, Campos J, Sherratt D, Cornet F, Mazel D, and Barre FX. The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae. Mol Cell. 2005 Aug 19;19(4):559-66. DOI:10.1016/j.molcel.2005.07.002 | PubMed ID:16109379 | HubMed [Paper5]
    The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae.
All Medline abstracts: PubMed | HubMed
  1. Bikard D, Julié-Galau S, Cambray G, and Mazel D. The synthetic integron: an in vivo genetic shuffling device. Nucleic Acids Res. 2010 Aug;38(15):e153. DOI:10.1093/nar/gkq511 | PubMed ID:20534632 | HubMed [Synthetic-Integron-2010]
  2. Bouvier M, Ducos-Galand M, Loot C, Bikard D, and Mazel D. Structural features of single-stranded integron cassette attC sites and their role in strand selection. PLoS Genet. 2009 Sep;5(9):e1000632. DOI:10.1371/journal.pgen.1000632 | PubMed ID:19730680 | HubMed [attC-2010]
  3. Bikard D, Patel D, Le Metté C, Giorgi V, Camilleri C, Bennett MJ, and Loudet O. Divergent evolution of duplicate genes leads to genetic incompatibilities within A. thaliana. Science. 2009 Jan 30;323(5914):623-6. DOI:10.1126/science.1165917 | PubMed ID:19179528 | HubMed [Weak-Root-2009]
  4. Bikard D, Képès F, and L'Equipe iGEM Paris.. [First French team success during iGEM synthetic biology competition]. Med Sci (Paris). 2008 May;24(5):541-4. DOI:10.1051/medsci/2008245541 | PubMed ID:18466734 | HubMed [iGEM-Paris-2007]
All Medline abstracts: PubMed | HubMed

Useful links