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<align=left><h1 style="color:maroon">Research</h1></align>
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Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:
- the modification of biochemical pathways inside cells and
- the rigorous evaluation of the resulting cellular phenotypes.
Our most recent research has been focused on the following topics:
- Metabolic Engineering of E.Coli for the production of biochemicals
- Inverse Metabolic Engineering
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To accomplish the above goals we make use of a diverse array of scientific tools and
methods, many of which have also become areas of research for our group:
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<b><a href="Bioinfo.shtml">Bioinformatics and Systems Biology</a></b> - Our group was
one of the first to realize the importance of computational tools for handling the
large volume of data generated by microarrays and other technologies.
<li>
<b><a href="Fluxes.shtml">Methods for intracellular flux determination</a></b>
- Fluxes are determined by material balancing, NMR fine spectra analysis and
GC-MS measurements.
<li>
<b><a href="Microarray.shtml">DNA microarrays</a></b> - We have developed full
genome microarrays for <i>Synechocystis</i> Sp., and partial microarrays for
<i>C. glutamicum</i>, <i>E. coli</i>, and the mouse genomes.
<li>
<b><a href="BioReactor.shtml">Bioreaction network analysis.</a></b>
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<font color="maroon"><tt>Address</tt></font><br>
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Massachusetts Institute of Technology<br>
Department of Chemical Engineering<br>
Cambridge, MA 02139<br>
Room 56-469
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<a href="http://www.mit.edu">MIT</a> | <a href="/wiki/Stephanopoulos_Lab">HOME</a><br>
Last Modified:<br>Monday, July 10th, 2006 - by <a href="Adrian.shtml">afi</a>.
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<font color="#990000"><tt>gnswebpage-www@mit.edu</tt></font>
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<font color="#990000"><tt>Telephones</tt><br></font>
<small>
office | 617.258.0398<br>
lab | 617.253.6591<br>
lab | 617.258.0349<br>
lab | 617.253.6521<br>
fax | 617.253.3122<br>
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