Difference between revisions of "Freimoser"

From OpenWetWare
Jump to: navigation, search
 
(33 intermediate revisions by the same user not shown)
Line 5: Line 5:
 
</script>
 
</script>
 
<script type="text/javascript">
 
<script type="text/javascript">
_uacct = "UA-564843-1";
+
_uacct = "UA-564843-2";
 
urchinTracker();
 
urchinTracker();
 
</script>
 
</script>
Line 11: Line 11:
  
 
{{Template:FreimoserTopTemplate}}
 
{{Template:FreimoserTopTemplate}}
 +
  
  
 
{| cellspacing="3"  
 
{| cellspacing="3"  
 
|- valign="top"
 
|- valign="top"
|width="100%" align="justify"|
+
 
<div style="clear: right; text-align: left; float: left; background-color: #ffff00; border: 5px; solid: #000000; padding: 3px 10px 3px 10px; margin: 12px 10px 0px 0px">
+
|width=170px class="MainPageBG"|
 +
<div style="padding: 10px 5px 5px 5px; margin: 0px 0px 0px 0px">
 +
 
 +
[[Image:Florian1.jpg|left]]
 +
</div>
 +
|width=280px class="MainPageBG"|
 +
 
 +
<div style="float: left; padding: 0px 5px 0px 5px; margin: 0px 0px 0px 0px">
 +
<h2><b>Florian M. Freimoser, PhD</b></h2>
 +
<h3>Institute of Plant Sciences</h3>
 +
<b>Biochemistry and Physiology of Plants</b>
 +
ETH Zurich, LFW D46.1<br>
 +
Universit&auml;tsstr. 2<br>
 +
CH-8092 Zurich<br>
 +
Switzerland
 +
<br>
 +
Tel: +41 +44 632 38 44<br>
 +
Fax: +41 +44 632 10 44<br>
 +
 
 +
Please also visit our [http://www.polyphosphate.ethz.ch/ other web site!]
 +
</div>
 +
|align="justify"|
 +
<div style="clear: right; text-align: left; float: left; background-color: #ffff00; border: 0px 5px 0px 0px; solid: #000000; padding: 0px 3px 0px 3px; margin: 0px 3px 0px 0px">
 
<h3>The molecule we study is so plain<br>
 
<h3>The molecule we study is so plain<br>
 
the inorganic polyphosphate chain</h3>
 
the inorganic polyphosphate chain</h3>
 
</div>
 
</div>
<div style="border: 5px; solid: #000000; padding: 5px 5px 5px 5px">
+
<div style="border: 5px; solid: #000000; padding: 0px 5px 5px 5px">
 
<font face="arial">
 
<font face="arial">
The focus of the research in
+
Our group studies a simple
our group is a simple
 
 
molecule: <strong>inorganic
 
molecule: <strong>inorganic
 
polyphosphate (poly P)</strong>.<br>
 
polyphosphate (poly P)</strong>.<br>
Line 29: Line 51:
 
phosphate residues
 
phosphate residues
 
(from three to more than a thousand) that are
 
(from three to more than a thousand) that are
linked by energy-rich phosphoanhydride bonds. It has been detected
+
linked by energy-rich phosphoanhydride bonds. It occurs ubiquitously in all living cells and regulates many molecular and biological processes. Nevertheless, poly P is scarcely studied and little is known about poly P metabolism and its exact molecular functions; especially in eukaryotes. In our group we have developed methods to quantify poly P, to stain and localize poly P and to screen for poly P binding proteins. We are using these tools to investigate poly P metabolism and functions in fungi, plants and algae. However, at the moment our main efforts are devoted to the study of poly P metabolism in the yeast ''Saccharomyces cerevisiae'' and of poly P in fungal cell walls.
in all organisms and living cells and was found in many organelles.
 
In eukaryotes, poly P is particularly
 
prominent in fungi, algae and trypanosomatids.
 
Poly P serves as a phosphate and energy store and regulates
 
enzymes, chromatin condensation
 
and translation. Poly P is also involved in bacterial pathogenicity,
 
survival during stationary phase in
 
bacteria and yeast, or the adaptation to alkaline and osmotic stress.
 
In the slime mold <i>Dictyostelium discoideum</i>, poly P regulates
 
development and predation behaviour, and in humans blood coagulation is
 
accelerated and fibrinolysis is delayed by poly P.
 
In our group we study poly P metabolism and functions in eukaryotes and
 
we work mostly with yeast, filamentous fungi and algae.
 
 
</font>
 
</font>
 +
</div>
 +
|}
 +
 +
{| cellspacing="3"
 +
|- valign="top"
 +
 +
|width=800px class="MainPageBG"|
 +
<div style="padding: 10px 5px 5px 5px; margin: 0px 0px 0px 0px">
 +
 
[[Image:polyphosphate.gif|center]]
 
[[Image:polyphosphate.gif|center]]
 
</div>
 
</div>
 
|}
 
|}
 +
 +
 
__NOTOC__
 
__NOTOC__

Latest revision as of 12:55, 7 May 2008

<html> <script src="http://www.google-analytics.com/urchin.js" type="text/javascript"> </script> <script type="text/javascript"> _uacct = "UA-564843-2"; urchinTracker(); </script> </html>

<html><style type='text/css'> A:link {

   text-decoration: underline;
   font-size: 10pt;
   font-style: normal;
   font-family: arial, trebuchet ms;
   color: #003399;

}

A:visited {

   text-decoration: underline;
   font-size: 10pt;
   font-style: normal;
   font-family: arial, trebuchet ms;
   color: #003399;

} A:active {

   text-decoration: none;
   background-color: #99ccff;
   color: #660099;

}

A:hover {

   text-decoration: none;
   color: #ff0033;

}

.navbar{

 padding: 0px;
 width: "100%";
 font-family: Arial;
 font-size: 10pt;

} </style></html>


Florian1.jpg

Florian M. Freimoser, PhD

Institute of Plant Sciences

Biochemistry and Physiology of Plants ETH Zurich, LFW D46.1
Universitätsstr. 2
CH-8092 Zurich
Switzerland
Tel: +41 +44 632 38 44
Fax: +41 +44 632 10 44

Please also visit our other web site!

The molecule we study is so plain
the inorganic polyphosphate chain

Our group studies a simple molecule: inorganic polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of phosphate residues (from three to more than a thousand) that are linked by energy-rich phosphoanhydride bonds. It occurs ubiquitously in all living cells and regulates many molecular and biological processes. Nevertheless, poly P is scarcely studied and little is known about poly P metabolism and its exact molecular functions; especially in eukaryotes. In our group we have developed methods to quantify poly P, to stain and localize poly P and to screen for poly P binding proteins. We are using these tools to investigate poly P metabolism and functions in fungi, plants and algae. However, at the moment our main efforts are devoted to the study of poly P metabolism in the yeast Saccharomyces cerevisiae and of poly P in fungal cell walls.

Polyphosphate.gif