User:Tkadm30/Notebook/Hypercomputation

Hypercomputation

Synaptic hypercomputation

The Synaptic Hypercomputation (SH) hypothesis states that the phase coherence of neural communication (synaptic plasticity) may emerges via long-range synchrony in the gamma range. This non-classical neurocomputational model is controlled by synaptic exocytosis, regulating neural communication in the brain. [1]

Pharmacological hypercomputation

• Is pharmacological hypercomputation (PH) a dopamine-mediated synaptic function? (exocytosis)
• THC may rewire the brain connectivity by enhancing functional NMDA expression. (Reference needed)

Neuronal phase coherence and synaptic transitions

Heteromeric transactivation of dopamine-CB1 receptors:

• How dopamine-CB1 heteromeric transactivation potentiate synaptic hypercomputation in the gamma band? [2]

Discussion

• Is neuronal hypercomputation a form of synaptic quantum tunnelling?
• What is biological hypercomputation?
• Is self-organized criticality (SOC) an evidence of biological hypercomputation?
• What is synaptic hypercomputation?
• What is biological phase coherence?

References

1. http://www.sciencedirect.com/science/article/pii/S0896627315008235

   Rhythms for Cognition: Communication through Coherence

2. http://molpharm.aspetjournals.org/content/67/5/1697.short

   Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Enhances Heterodimer Formation: A Mechanism for Receptor Cross-Talk?

3. https://www.ncbi.nlm.nih.gov/pubmed/17035546

   Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

See also

• Endocannabinoids Notebook