6.021/Notes/2006-11-03

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Hodgkin-Huxley

  • Each factor can also be written as rates
  • The effect of temperature is to multiple rates by
  • An increase in temperature decreases all 3 time constants but has no effect on the final values.
  • At high temperature, no action potential is seen
  • There's another time constant due to capacitance in membrance
  • Changes in conductances have time delay before membrane potential changes
  • (membrane "RC" time constant) is about 1-2 ms.
  • increase in temperature causes the wave to catch up with the wave
  • As increase temperature, both approach . If waves go at same speed, cannot have action potential.