User:Tyou

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Tao You 游涛


Research Interest

1. Modelling and simulation of biomolecular network kinetics in Saccharomyces cerevisiae and Candida albicans

2. Deterministic and stochastic chemical kinetics, simulation algorithms, parameter estimation

3. Other Systems Biology areas


Publications

Journal Papers

  1. Bi X, Lin Q, Foo TW, Joshi S, You T, Shen HM, Ong CN, Cheah PY, Eu KW, and Hew CL. Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis. Mol Cell Proteomics. 2006 Jun;5(6):1119-30. DOI:10.1074/mcp.M500432-MCP200 | PubMed ID:16554294 | HubMed [Tao-MCP-2006]
  2. Lo SL, You T, Lin Q, Joshi SB, Chung MC, and Hew CL. SPLASH: systematic proteomics laboratory analysis and storage hub. Proteomics. 2006 Mar;6(6):1758-69. DOI:10.1002/pmic.200500378 | PubMed ID:16456885 | HubMed [Tao-Proteomics-2006]

All Medline abstracts: PubMed | HubMed


Conference Posters

BioSysBio, Manchester (1/2007)

1. Tao You, Alistair Brown, George Coghill, A Quantitative Model for the GCN4 Translational Control in Saccharomyces cerevisiae


3rd International Conference on Structural Biology and Functional Genomics, Singapore (12/2004)

2. Tao You, Siaw Ling Lo, et al, A systematic method to analyze onco-proteomics data based on the Merlion system and Gene Ontology

3. Siaw Ling Lo, Tao You, et al, Merlion: An XML system based on a practical customization of PEDRo data model


HUPO 3rd Annual World Congress, Beijing (10/2004)

4. Tao You, Siaw Ling Lo, et al, Merlion: A proteomics database query system

5. Qingsong Lin, Tao You, et al, Quantitative proteomics investigation of colorectal cancer using ICAT and LC-MALDI TOF/TOF MS


Teaching & Talks

1. Systems Biology Training Session, Joint Meeting of EC Galar Fungail with EU CanTrain, Crete (9/2006)

Kinetic model: what, why, and how


2. 1st International Cancer Biomarker Consortium Meeting, Seoul (8/2005)

SPLASH: Systematic Proteomics Laboratory Analysis and Storage Hub


3. Journal Club, Department of Biological Sciences, NUS, Singapore (3/2004)

Analysis of integral feedback control in a robust system: what is right and what is wrong?


Education

University of Aberdeen, UK (10/2005 - Now)

PhD Student (Systems Biology)


Singapore-MIT Alliance, Singapore (7/2002-7/2003)

Master of Science, Molecular Engineering in Biological and Chemical Systems


Tsinghua University, Beijing (9/1998-7/2002)

Bachelor of Engineering, Polymer Science and Engineering


Work Experience

Research Assistant, Department of Biological Sciences, NUS, Singapore (9/2003- 10/2005)

1. Development of the SPLASH XML system which is compliant with PEDRo format, for large-scale proteomics data management, exchange and analysis

2. Systems-level analyses of onco-proteomics data based on biochemical pathway information, statistics-associated Gene Ontology annotations, and genome-scale biomolecular interaction networks

3. Onco-proteomics experiments on colorectal cancer


Awards & Honours

Overseas Research Students Awards Scheme, Scottish Funding Council (9/2006)

Sixth Century Studentship, University of Aberdeen (10/2005)

2004 HUPO World Congress Young Investigator Award (10/2004)

Singapore-MIT Alliance Scholarship (7/2002)


Contact

Microbiology Theme, Room 250, Institute of Medical Sciences, Foresterhill

University of Aberdeen, Aberdeen, UK AB25 2ZD

Tel: +44 (0)1224 555888


Department of Computing Science, Room 310, Meston Building, Meston Walk

University of Aberdeen, Aberdeen, UK AB24 3UE

Tel: +44 (0)1224 272457

Email: t dot you at abdn dot ac dot uk