User:Shicheng Guo
Contact Info
- Shicheng Guo, Ph.D.
- https://shicheng-guo.github.io/about
- University of California at San Diego, UCSD
- 9500 Gilman Drive MC 0412. La Jolla, San Diego, CA 92093-0412
Education
- 2009-2014, PhD, Genetics, School of Life Sciences, Fudan University, Shanghai, China
- 2005-2009, BS, Bio-technique, School of Life Sciences, Northeast Agricultural University,Harbin, China
Research interests
Shicheng Guo, Ph.D. (2009-2014), Postdoc fellow in UCSD. He graduated from School of Life Sciences, Fudan University. The realm which he focus on now is computational biology and medical statistics including: manifold kinds of microarray analysis, meta-analysis, genome-wide SNP, RNA, Methylation, CNV analysis based on next generation sequencing technology. In the past three years, he had participated in series of attractive research( Yan-Huang methylome project et.al), and participated in publishing several interesting papers( Nature Biotechnology, Plos Biology et al) and two Chinese patents. Specially, in clinical field, he want to explore some high sensitive and specific diagnosis and prognosis biomarkers for some complex disease such as immune diseases, cancer. And then establish some high accuracy disease prediction models so that doctors can make more felicitous decision to his/her patients. 5 years Perl, R usage exprience under Ubuntu.
Bioinformatic Analysis
- Methylation Beadchip
- NGS Methylation Analsyis
- NGS RNA-seq Analsyis
- NGS Genetic Variation Analsyis
- Functional Genetics Models of Human Disease
- Genetics and Epigenetics of RNA Methylation System in Human Cancers
- Computational and Systematic Analysis of Multi-omics Data for Drug Discovery and Development
- Identifying the Key Pathogenic Factors of Neurological Disorders by Integrating Multi-omics Data
Research Projects
- Computational Approach based Drug Discovery and Development
- Immunity and Human Disease: Pathogenesis and Drug Target
Architecture Systems
- Linux,PBS,Bash,awk,sed,perl,python,R
- Machine learning for variable selection and prediction
- Genetic and Epigenetic Association Study
- Gitlab and Github to build, save and share software and pipeline
- Dynamic Documents with Markdown, knitr
- Rpubs to save and share Projects analyzed by R
- OpenWetWare,MediaWiki,Biostars to share the knowledge