User:Richard D Haigh

Contact Info

Richard D Haigh (an artistic interpretation)

• Richard D Haigh
• Department of Genetics, University of Leicester
• Address 1
• Address 2
• City, State, Country etc.
• Email me through OpenWetWare

I work in the Department of Genetics at the University of Leicester. I learned about OpenWetWare from Pure chance from google - but I have just bounced the url around the department, and I've joined because I'm a microbiologist with 20 years of practical bench experience , I spend much of my time passing on molecular biology lab skills to grad students so I probably have something to offer..

Education

• 1999, PhD, University of Leicester
• 1986, BSc, Biochemistry, University of Newcastle upon Tyne

Research interests

1. Interest 1
2. Interest 2
3. Interest 3

Publications

1. Freestone PP, Haigh RD, and Lyte M. Catecholamine inotrope resuscitation of antibiotic-damaged staphylococci and its blockade by specific receptor antagonists. J Infect Dis. 2008 Apr 1;197(7):1044-52. DOI:10.1086/529202 |
2. Freestone PP, Sandrini SM, Haigh RD, and Lyte M. Microbial endocrinology: how stress influences susceptibility to infection. Trends Microbiol. 2008 Feb;16(2):55-64. DOI:10.1016/j.tim.2007.11.005 |
3. Pagaling E, Haigh RD, Grant WD, Cowan DA, Jones BE, Ma Y, Ventosa A, and Heaphy S. Sequence analysis of an Archaeal virus isolated from a hypersaline lake in Inner Mongolia, China. BMC Genomics. 2007 Nov 9;8:410. DOI:10.1186/1471-2164-8-410 |
4. Freestone PP, Walton NJ, Haigh RD, and Lyte M. Influence of dietary catechols on the growth of enteropathogenic bacteria. Int J Food Microbiol. 2007 Nov 1;119(3):159-69. DOI:10.1016/j.ijfoodmicro.2007.07.039 |
5. Freestone PP, Haigh RD, and Lyte M. Blockade of catecholamine-induced growth by adrenergic and dopaminergic receptor antagonists in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica. BMC Microbiol. 2007 Jan 30;7:8. DOI:10.1186/1471-2180-7-8 |
6. Freestone PP, Haigh RD, and Lyte M. Specificity of catecholamine-induced growth in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica. FEMS Microbiol Lett. 2007 Apr;269(2):221-8. DOI:10.1111/j.1574-6968.2006.00619.x |
7. Clarke SC, Haigh RD, Freestone PP, and Williams PH. Virulence of enteropathogenic Escherichia coli, a global pathogen. Clin Microbiol Rev. 2003 Jul;16(3):365-78. DOI:10.1128/CMR.16.3.365-378.2003 |
8. Freestone PP, Haigh RD, Williams PH, and Lyte M. Involvement of enterobactin in norepinephrine-mediated iron supply from transferrin to enterohaemorrhagic Escherichia coli. FEMS Microbiol Lett. 2003 May 16;222(1):39-43. DOI:10.1016/S0378-1097(03)00243-X |
9. Lyte M, Freestone PP, Neal CP, Olson BA, Haigh RD, Bayston R, and Williams PH. Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes. Lancet. 2003 Jan 11;361(9352):130-5. DOI:10.1016/S0140-6736(03)12231-3 |
10. Freestone PP, Williams PH, Haigh RD, Maggs AF, Neal CP, and Lyte M. Growth stimulation of intestinal commensal Escherichia coli by catecholamines: a possible contributory factor in trauma-induced sepsis. Shock. 2002 Nov;18(5):465-70. DOI:10.1097/00024382-200211000-00014 |
11. Reissbrodt R, Rienaecker I, Romanova JM, Freestone PP, Haigh RD, Lyte M, Tschäpe H, and Williams PH. Resuscitation of Salmonella enterica serovar typhimurium and enterohemorrhagic Escherichia coli from the viable but nonculturable state by heat-stable enterobacterial autoinducer. Appl Environ Microbiol. 2002 Oct;68(10):4788-94. DOI:10.1128/AEM.68.10.4788-4794.2002 |
12. Clarke SC, Haigh RD, Freestone PP, and Williams PH. Enteropathogenic Escherichia coli infection: history and clinical aspects. Br J Biomed Sci. 2002;59(2):123-7. DOI:10.1080/09674845.2002.11783647 |
13. Neal CP, Freestone PP, Maggs AF, Haigh RD, Williams PH, and Lyte M. Catecholamine inotropes as growth factors for Staphylococcus epidermidis and other coagulase-negative staphylococci. FEMS Microbiol Lett. 2001 Jan 15;194(2):163-9. DOI:10.1111/j.1574-6968.2001.tb09463.x |
14. Grant AJ, Haigh R, Williams P, and O'Connor CD. An in vitro transposon system for highly regulated gene expression: construction of Escherichia coli strains with arabinose-dependent growth at low temperatures. Gene. 2001 Dec 12;280(1-2):145-51. DOI:10.1016/s0378-1119(01)00769-7 |
15. Kumar SS, Malladi V, Sankaran K, Haigh R, Williams P, and Balakrishnan A. Extrusion of actin-positive strands from Hep-2 and Int 407 cells caused by outer membrane preparations of enteropathogenic Escherichia coil and specific attachment of wild type bacteria to the strands. Can J Microbiol. 2001 Aug;47(8):727-34.
16. Kumar SS, Sankaran K, Haigh R, Williams PH, and Balakrishnan A. Cytopathic effects of outer-membrane preparations of enteropathogenic Escherichia coli and co-expression of maltoporin with secretory virulence factor, EspB. J Med Microbiol. 2001 Jul;50(7):602-612. DOI:10.1099/0022-1317-50-7-602 |
17. Freestone PP, Lyte M, Neal CP, Maggs AF, Haigh RD, and Williams PH. The mammalian neuroendocrine hormone norepinephrine supplies iron for bacterial growth in the presence of transferrin or lactoferrin. J Bacteriol. 2000 Nov;182(21):6091-8. DOI:10.1128/JB.182.21.6091-6098.2000 |
18. Freestone PP, Haigh RD, Williams PH, and Lyte M. Stimulation of bacterial growth by heat-stable, norepinephrine-induced autoinducers. FEMS Microbiol Lett. 1999 Mar 1;172(1):53-60. DOI:10.1111/j.1574-6968.1999.tb13449.x |
19. Haigh RD and Williams PH. CO2 regulation of virulence genes in enteropathogenic Escherichia coli. Adv Exp Med Biol. 1997;412:253-6. DOI:10.1007/978-1-4899-1828-4_39 |
20. Manjarrez-Hernandez HA, Baldwin TJ, Williams PH, Haigh R, Knutton S, and Aitken A. Phosphorylation of myosin light chain at distinct sites and its association with the cytoskeleton during enteropathogenic Escherichia coli infection. Infect Immun. 1996 Jun;64(6):2368-70. DOI:10.1128/iai.64.6.2368-2370.1996 |
21. Baldwin TJ, Knutton S, Haigh R, Williams PH, Palmer HM, Aitken A, and Borriello SP. Hijacking host cell signal transduction mechanisms during infection with enteropathogenic Escherichia coli. Biochem Soc Trans. 1996 May;24(2):552-8. DOI:10.1042/bst0240552 |
22. Haigh R, Baldwin T, Knutton S, and Williams PH. Carbon dioxide regulated secretion of the EaeB protein of enteropathogenic Escherichia coli. FEMS Microbiol Lett. 1995 Jun 1;129(1):63-7. DOI:10.1016/0378-1097(95)00136-S |
23. Kenny B, Haigh R, and Holland IB. Analysis of the haemolysin transport process through the secretion from Escherichia coli of PCM, CAT or beta-galactosidase fused to the Hly C-terminal signal domain. Mol Microbiol. 1991 Oct;5(10):2557-68. DOI:10.1111/j.1365-2958.1991.tb02102.x |
24. Gray L, Baker K, Kenny B, Mackman N, Haigh R, and Holland IB. A novel C-terminal signal sequence targets Escherichia coli haemolysin directly to the medium. J Cell Sci Suppl. 1989;11:45-57. DOI:10.1242/jcs.1989.supplement_11.4 |
25. Mackman N, Baker K, Gray L, Haigh R, Nicaud JM, and Holland IB. Release of a chimeric protein into the medium from Escherichia coli using the C-terminal secretion signal of haemolysin. EMBO J. 1987 Sep;6(9):2835-41. DOI:10.1002/j.1460-2075.1987.tb02580.x |

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