User:Ian T. Suydam

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Curriculum vitae

Ian T. Suydam Curriculum vitae

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Ian T. Suydam
Ian T. Suydam
  • This site was last updated on December 01, 2014

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Contact Info

Education

  • 2009, Postdoctoral Fellow, Molecular Biophysics and Biochemistry, Yale University
  • 2005, PhD, Chemistry, Stanford University
  • 1998, BA, Chemistry, Bard College

Research interests

  1. Electrostatics and pKa Perturbations in Structured Biopolymers
  2. Synthesis of Riboswitch Binding Metabolites and Modified Analogs
  3. Molecular Determinants of Small Molecular Binding to Folded RNA
  4. Thermodynamics and Kinetics of RNA Folding

Publications

5. Suydam, I. T., Levandoski, S. D., and Strobel, S. A. (2010) Catalytic Importance of a Protonated Adenosine in the Hairpin Ribozyme Active Site, Biochemistry 49, 3723-3732.

4. Suydam, I. T., and Strobel, S. A. (2009) Nucleotide Analog Interference Mapping, Methods Enzymol. 468, 3-30.

3. Suydam, I. T., and Strobel, S. A. (2008) Fluorine substituted adenosines as probes of nucleobase protonation in functional RNAs, J. Am. Chem. Soc. 130, 13639-13648.

2. Suydam, I. T., Snow, C. D., Pande, V. S., and Boxer, S. G. (2006) Electric fields at the active site of an enzyme: Direct comparison of experiment with theory, Science 313, 200-204.

1. Suydam, I. T., and Boxer, S. G. (2003) Vibrational Stark effects calibrate the sensitivity of vibrational probes for electric fields in proteins, Biochemistry 42, 12050-12055.

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