Taylor:Publications

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PUBLICATIONS

303. Hate, S. S., Reutzel-Edens, S. M., and Taylor, L. S. (2020). Interplay of Adsorption, Supersaturation and the Presence of an Absorptive Sink on Drug Release from Mesoporous Silica-Based Formulations. Pharmaceutical Research. 37(8):163 1-18. http://dx.doi.org/10.1007/s11095-020-02879-9

302. Ueda, K., and Taylor, L. S. (2020). Impact of hypromellose acetate succinate grade on drug amorphous solubility and in vitro membrane transport. Journal of Pharmaceutical Sciences. 109(8): 2464-2473. http://dx.doi.org/10.1016/j.xphs.2020.04.014

301. McCarthy, C. A., Zemlyanov, D., Crean, A. M., Taylor, L. S. (2020). Comparison of Drug Release and Adsorption Under Supersaturating Conditions for Ordered Mesoporous Silica with Indomethacin or Indomethacin Methyl Ester. Molecular Pharmaceutics. 17(8): 3062–3074. http://dx.doi.org/10.1021/acs.molpharmaceut.0c00489

300. Enright, E. F., Joyce, S. A., Gahan, C. G. M., Taylor, L. S. (2020) Impact of phospholipid digests and bile acid pool variations on the crystallization of atazanavir from supersaturated solutions. European Journal of Pharmaceutics and Biopharmaceutics. 153: 68-83. http://dx.doi.org/10.1016/j.ejpb.2020.05.022

299. Parker, A. S., Taylor, L. S., and Beaudoin, S. P. (2020). The Role of Surface Energy Heterogeneity on Crystal Morphology during Solid-State Crystallization at the Amorphous Atazanavir-Water Interface. CrysEngComm. 22, 3179-3187. http://dx.doi.org/10.1039/C9CE02007A

298. Trasi, N. S., Bhujbal, S.V., Zhou, Q. T., and Taylor, L. S. (2020). Physical Stability and Release Properties of Lumefantrine Amorphous Solid Dispersion Granules Prepared by a Simple Solvent Evaporation Approach. International Journal of Pharmaceutical Sciences X, 100052. http://dx.doi.org/10.1016/j.ijpx.2020.100052

297. Que, C., Qi, Q., Zemlyanov, D. Y., Mo, H., Deac, A., Zeller, M., Indulkar, A. S., Gao, Y,. Zhang, G. G. Z., and Taylor, L. S. (2020). Evidence for Halogen Bonding in Amorphous Solid Dispersions. Crystal Growth and Design. 20 (5): 3224–3235. http://dx.doi.org/10.1021/acs.cgd.0c00073

296. Saboo, S. S., Kestur, U. S., Flaherty, D. P., Taylor, L. S. (2020) Congruent release of drug and polymer from amorphous solid dispersions: insights into the role of drug-polymer hydrogen bonding, surface crystallization and glass transition. Molecular Pharmaceutics. 17(4): 1261–1275. http://dx.doi.org/10.1021/acs.molpharmaceut.9b01272

295. Ueda, K., and Taylor, L. S. (2020). Polymer type impacts amorphous solubility and drug-rich phase colloidal stability: A mechanistic study using nuclear magnetic resonance spectroscopy. Molecular Pharmaceutics. 17(4):1352-1362 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00061

294. Moseson, D.E., Parker, A.S., Beaudoin, S.P., and Taylor, L.S., (2020) Amorphous Solid Dispersions Containing Residual Crystallinity: Influence of Seed Properties and Polymer Adsorption on Dissolution Performance. European Journal of Pharmaceutical Sciences. 146: 105276. http://dx.doi.org/10.1016/j.ejps.2020.105276

293. Wilson, N.E., Mutukuri, T.T., Zemlyanov, D.Y., Taylor, L. S., Topp, E.M., Zhou, Q. T. (2020). Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying. Pharmaceutical Research. 37(1):14. http://dx.doi.org/10.1007/s11095-019-2738-9

292. Sherman, A. M., Geiger, A. C., Smith, C.,Taylor, L. S. Hinds, J., Stroud, P., Simpson, G. J. (2020). Stochastic Differential Scanning Calorimetry by Nonlinear Optical Microscopy. Analytical Chemistry. 92(1): 1171-1178. http://dx.doi.org/10.1021/acs.analchem.9b04300

291. Hate, S. S., Reutzel-Edens, S. M., and Taylor, L. S. (2020). Absorptive dissolution testing: An improved approach to study the impact of residual crystallinity on the performance of amorphous formulations. Journal of Pharmaceutical Sciences. 109(3): 1312-1323. http://dx.doi.org/10.1016/j.xphs.2019.11.016.

290. Indulkar, A. S., Raina, S. A., Gao, Y., Zhang, G. G. Z., and Taylor, L. S. (2020). Impact of monomeric vs. micellar surfactant and surfactant-polymer interactions on nucleation-induction times of atazanavir from supersaturated solutions. Crystal Growth and Design. 20(1):62-72. http://dx.doi.org/10.1021/acs.cgd.9b00482

289. Trasi, N. S., Bhujbal, S.V., Zhou, Q. T., and Taylor, L. S. (2019). Amorphous Solid Dispersion Formation via Solvent Granulation – A Case Study with Ritonavir and Lopinavir. International Journal of Pharmaceutics. X 1, 100035. http://dx.doi.org/10.1016/j.ijpx.2019.100035

288. Que, C., Lou, X., Zemlyanov, D. Y., Mo, H., Indulkar, A. S., Gao, Y., Zhang, G. G. Z. and Taylor, L. S. (2019). Insights into the Dissolution Behavior of Ledipasvir-Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions. Molecular Pharmaceutics. 16(12):5054-5067. http://dx.doi.org/10.1021/acs.molpharmaceut.9b01025

287. Elkhabaz, A., Sarkar, S., Simpson, G. J., and Taylor, L.S. (2019). Characterization of Phase Transformations for Amorphous Solid Dispersions of a Weakly Basic Drug upon Dissolution in Biorelevant Media. Pharmaceutical Research. 36 (12), 174. http://dx.doi.org/10.1007/s11095-019-2718-0

286. Tres, F., Posada, M. M., Hall, S. D., Mohutsky, M. A., and Taylor, L. S. (2019). The Effect of Promiscuous Aggregation on In Vitro Drug Metabolism Assays. Pharmaceutical Research. 36 (12), 170. http://dx.doi.org/10.1007/s11095-019-2713-5

285. Elkhabaz, A., Moseson, D. E., Brouwers, J., Augustijns, P., and Taylor, L.S. (2019). Interplay of supersaturation and solubilization: Lack of correlation between concentration-based supersaturation measurements and membrane transport rates in simulated and aspirated human fluids. Molecular Pharmaceutics. 16 (12):5042-5053. https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b00956

284. Voelker, A.L., Verbeek, G., Taylor, L. S. and Mauer, L. J. (2019). Effects of emulsifiers on the moisture sorption and crystallization of amorphous sucrose lyophiles. Food Chemistry. 3:100050. http://dx.doi.org/10.1016/j.fochx.2019.100050

283. Purohit, H.S., Trasi, N.S., Osterling, D.J., Stolarik, D.F., Jenkins, G.J., Gao, W., Zhang, G.G.Z., Taylor, L.S. (2019). Assessing the Impact of Endogenously Derived Crystalline Drug on the in Vivo Performance of Amorphous Formulations. Molecular Pharmaceutics. http://dx.doi.org/10.1021/acs.molpharmaceut.9b00455

282. Dening, T.J., Zemlyanov, D., Taylor, L.S. (2019). Application of an adsorption isotherm to explain incomplete drug release from ordered mesoporous silica materials under supersaturating conditions. Journal of Controlled Release. 307:186-199. http://dx.doi.org/10.1016/j.jconrel.2019.06.028

281. Dong, Y., Novo, D.C., Mosquera-Giraldo, L.I., Taylor, L.S., and Edgar, K. J. (2019). Cellulose-Bile Ester Conjugates by Olefin Cross-metathesis: A CM Strategy for Access to Complex Polysaccharide Structures. Carbohydrate Polymers 221: 37-47. http://dx.doi.org/10.1016/j.carbpol.2019.05.061

280. Moseson, D. E., Parker, A. S., Gilpin, C. J., Stewart, A. A., Beaudoin, S. P. and Taylor, L. S. (2019). Dissolution of Indomethacin Crystals into a Polymer Melt: Role of Diffusion and Fragmentation. Crystal Growth and Design.19:3315-3328. http://dx.doi.org/10.1021/acs.cgd.9b00200

279. Li, N., and Taylor, L.S. (2019). Microstructure Formation for Improved Dissolution Performance of Lopinavir Amorphous Solid Dispersions. Molecular Pharmaceutics. http://dx.doi.org/10.1021/acs.molpharmaceut.9b00117

278. Saboo, S., Mugheirbi, N. A., Zemlyanov, D.Y., Kestur, U. S., and Taylor, L. S. (2019) Congruent release of drug and polymer: A “sweet spot” in the dissolution of amorphous solid dispersions. Journal of Controlled Release. 298:68-82. http://dx.doi.org/10.1016/j.jconrel.2019.01.039

277. Indulkar, A. S., Lou, X., Zhang, G. G. Z., and Taylor, L. S. (2019). Insights into the dissolution mechanism of ritonavir-copovidone amorphous solid dispersions: importance of congruent release for enhanced performance. Molecular Pharmaceutics. 16(3):1327-1339.http://dx.doi.org/10.1021/acs.molpharmaceut.8b01261

276. Mauer, L. J., Forny, L., Meunier, V., and Taylor, L. S. (2019). Optimizing the quality of dry ingredient blends and powder products: the challenges of moisture-mediated phase transformations. Annual Review of Food Science and Technology. 10:457-478. http://dx.doi.org/10.1146/annurev-food-032818-121224

275. Hate, S. S., Reutzel-Edens, S. M., and Taylor, L. S. (2019). Insight into Amorphous Solid Dispersion Performance by Coupled Dissolution and Membrane Mass Transfer Measurements. Molecular Pharmaceutics. 16(1):448-461. http://dx.doi.org/10.1021/acs.molpharmaceut.8b01117

274. Wilson, V. Lou, X., Osterling, D. J., Stolarik, D. F., Jenkins, G., Gao, W., Zhang, G. G. Z., and Taylor, L. S. (2018). Relationship between amorphous solid dispersion in vivo absorption and in vitro dissolution: phase behavior during dissolution, speciation, and membrane mass transport. Journal of Controlled Release. 292:172-182.. http://dx.doi.org/10.1016/j.jconrel.2018.11.003

273. Hsu, H., Taylor, L. S., and Harris, M. T. (2018). Impact of Additives on Heterogeneous Crystallization of Acetaminophen. International Journal of Chemical Engineering. http://dx.doi.org/10.1155/2018/3604320

272. Mosquera-Giraldo, L. I., Borca, C. H., Parker, A. S., Dong, Y., Edgar, K. J., Beaudoin, S. P., Slipchenko, L.V, and Taylor, L. S. (2018). Crystallization Inhibition Properties of Cellulose Esters and Ethers for a Group of Chemically Diverse Drugs - Experimental and Computational Insight. Biomacromolecules. 19(12):4593-4606 http://dx.doi.org/10.1021/acs.biomac.8b01280

271. Moseson, D. E., Mugheirbi, N. A., Stewart, A. A., and Taylor, L. S. (2018) Nanometer-Scale Residual Crystals in a Hot Melt Extruded Amorphous Solid Dispersion: Characterization by Transmission Electron Microscopy. Crystal Growth and Design. 18(12):7633-7640. http://dx.doi.org/10.1021/acs.cgd.8b01435

270. Moseson, D. E. and Taylor, L. S. (2018). The application of temperature-composition phase diagrams for hot melt extrusion processing of amorphous solid dispersions to prevent residual crystallinity. International Journal of Pharmaceutics. 553(1-2):454-466. http://dx.doi.org/10.1016/j.ijpharm.2018.10.055

269. Patel, M. A., Luthra, S., Shamblin, S. L., Arora, K., Krzyzaniak, J. F., and Taylor, L. S. (2018). Assessing the risk of salt disproportionation using crystal structure and surface topography analysis. Crystal Growth and Design. 18(11):7027-7040. http://dx.doi.org/10.1021/acs.cgd.8b01188

268. Thorat, A. A., Forny, L., Meunier, V., Taylor, L. S., and Mauer, L. J. (2018). Effects of Mono-, Di-, and Tri-saccharides on the Stability and Crystallization of Amorphous Sucrose. Journal of Food Science. 83(11):2827-2839. http://dx.doi.org/10.1111/1750-3841.14357

267. Dening, T. J., and Taylor, L. S. Supersaturation Potential of Ordered Mesoporous Silica Delivery Systems. Part 1: Dissolution Performance and Drug Membrane Transport Rates. (2018) Molecular Pharmaceutics. 15(8):3489-3501. http://dx.doi.org/10.1021/acs.molpharmaceut.8b00488

266. Voelker, A., Miller, J., Running, C.A., Taylor, L. S. and Mauer, L. J. Chemical stability and reaction kinetics of two thiamine salts (thiamine mononitrate and thiamine chloride hydrochloride) in solution. (2018). Food Research International. 112:443-456. http://dx.doi.org/10.1016/j.foodres.2018.06.056

265. Indulkar, A. S., Gao, Y., Raina, S. A., Zhang, G. G. Z., and Taylor, L. S.(2018). Crystallization from supersaturated solutions: Role of lecithin and composite simulated intestinal fluid. Pharmaceutical Research. 35(8):158. http://dx.doi.org/10.1007/s11095-018-2441-2

264. Mugheirbi, N. A., Mosquera-Giraldo, L. I., Borca, , Slipchenko, L.V, and Taylor, L. S. (2018). Phase Behavior of Drug-Hydroxypropyl Methylcellulose Amorphous Solid Dispersions Produced from Various Solvent Systems: Mechanistic Understanding of the Role of Polymer using Experimental and Theoretical Methods. Molecular Pharmaceutics. 15(8):3236-3251. http://dx.doi.org/10.1021/acs.molpharmaceut.8b00324

263. Arca, H., C., Bi, V., Mosquera-Giraldo, L. I., Xu, D., Taylor, L. S., and Edgar, K. J. (2018). Pharmaceutical Applications of Cellulose Ethers and Cellulose Ether Esters.Biomacromolecules. 19(7):2351-2376. http://dx.doi.org/10.1021/acs.biomac.8b00517

262. Patel, M. A., Luthra, S., Shamblin, S. L., Arora, K., Krzyzaniak, J. F., and Taylor, L. S. (2018).Effect of excipient properties, water activity, and water content on the disproportionation of a pharmaceutical salt. International Journal of Pharmaceutics. 546 (1-2): 226-234. http://dx.doi.org/10.1016/j.ijpharm.2018.05.035

261. Bhujbal, S.V., Zemlyanov, D.Y., Cavallaro, A., Mangal, S., Taylor, L. S. and Zhou, Q. T. (2018). Qualitative and Quantitative Characterization of Composition Heterogeneity on the Surface of Spray Dried Amorphous Solid Dispersion Particles by an Advanced Surface Analysis Platform with High Surface Sensitivity and Superior Spatial Resolution. Molecular Pharmaceutics. 15(5):2045-2053. http://dx.doi.org/10.1021/acs.molpharmaceut.8b00122

260. Li, N., and Taylor, L.S. Tailoring supersaturation from amorphous solid dispersions. (2018) Journal of Controlled Release. http://dx.doi.org/10.1016/j.jconrel.2018.04.014

259. Tres, F., Posada, M. M., Hall, S. D., Mohutsky, M. A., and Taylor, L. S. (2018). Mechanistic Understanding of the Phase Behavior of Supersaturated Solutions of Poorly Water-Soluble Drugs. International Journal of Pharmaceutics. 543 (1-2):29-37. http://dx.doi.org/10.1016/j.ijpharm.2018.03.038

258. Mosquera-Giraldo, L. I., Li, N., Wilson, V. R., Nichols, B. L. B., Edgar, K. J., and Taylor, L. S. (2018). Influence of Polymer and Drug Loading on the Release Profile and Membrane Transport of Telaprevir. Molecular Pharmaceutics. 15(4):1700-1713. http://dx.doi.org/10.1021/acs.molpharmaceut.8b00104

257. Sugihara, H. and Taylor, L. S. (2018). Evaluation of Pazopanib Phase Behavior Following pH-Induced Supersaturation. Molecular Pharmaceutics. 15(4):1690-1699 http://dx.doi.org/10.1021/acs.molpharmaceut.8b00081

256. Liu, S., Gao, C., Mosquera-Giraldo, L. I., Taylor, L. S., and Edgar, K. J. (2018). Selective Synthesis of Curdlan Omega Carboxyamides by Staudinger Ylide Nucleophilic Ring-opening. Carbohydrate Polymers. 190:222-231. http://dx.doi.org/10.1016/j.carbpol.2018.02.074

255. Que, C., Gao, Y., Raina, S. A., Zhang, G. Z. Z., and Taylor, L. S. (2018). Paclitaxel Crystal Seeds with Different Intrinsic Properties and Their Impact on Dissolution of Paclitaxel-HPMCAS Amorphous Solid Dispersions. Crystal Growth and Design. 18(3):1548-1559. http://dx.doi.org/10.1021/acs.cgd.7b01521

254. Bhardwaj, V., Trasi, N. S., Zemlyanov, D. Y., and Taylor, L. S. (2018). Surface area normalized dissolution to study differences in itraconazole-copovidone solid dispersions prepared by spray-drying and hot melt extrusion. International Journal of Pharmaceutics. 540(1-2):106-119. http://dx.doi.org/10.1016/j.ijpharm.2018.02.005

253. Purohit, H., Trasi, N. S., Sun, D. D., Chow, E. C. Y., Wen, H., Zhang, X., Gao, Y., and Taylor, L. S.(2018). Investigating the impact of drug crystallinity in amorphous tacrolimus capsules on pharmacokinetics and bioequivalence using discriminatory in vitro dissolution testing and PBPK modeling and simulation. Journal of Pharmaceutical Sciences. 107(5):1330-1341. http://dx.doi.org/10.1016/j.xphs.2017.12.024

252. Tres, F., Hall, S. D., Mohutsky, M. A., and Taylor, L. S. (2018). Monitoring the Phase Behavior of Supersaturated Solutions of Poorly Water-Soluble Drugs Using Fluorescence Techniques. Journal of Pharmaceutical Sciences. 107(1):94-102. http://dx.doi.org/10.1016/j.xphs.2017.10.002

251. Winslow, C. J., Nichols, B. L. B, Novo, D. C. , Mosquera-Giraldo, L. I. , Taylor, L. S., Edgar, K. J., and Neilson, A. P. (2018). Cellulose-based amorphous solid dispersions enhance rifapentine delivery characteristics in vitro. Carbohydrate Polymers. 182(15):149-158. http://dx.doi.org/10.1016/j.carbpol.2017.11.024

250. Patel, M. A., Luthra, S., Shamblin, S. L., Arora, K., Krzyzaniak, J. F., and Taylor, L. S. (2018) Impact of solid-state form on the disproportionation of miconazole mesylate. Molecular Pharmaceutics. 15(1):40-52. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00694

249. Kalra, A., Luner, P., Taylor, L. S., Byrn, S. R., and Li, T. (2018). Gaining Thermodynamic Insight from Distinct Glass Formation Kinetics of Structurally Similar Organic Compounds. Journal of Pharmaceutical Sciences. 107(1):192-202. http://dx.doi.org/10.1016/j.xphs.2017.06.012

248. Elkhabaz, A., Sarkar, S., Dinh, J. K., Simpson, G. J., and Taylor, L.S. (2018) Variation in the Supersaturation and Phase Behavior of Ezetimibe Amorphous Solid Dispersions Upon Dissolution in Different Biorelevant Media. Molecular Pharmaceutics. 15(1):193-206. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00814

247. Arca, H., C., Mosquera-Giraldo, L. I., Pereira, J. M. Sriranganathan, N., Taylor, L. S., Edgar, K. J. (2018). Rifampin Stability and Solution Concentration Enhancement through Amorphous Solid Dispersion in Cellulose ω-Carboxyalkanoate Matrices. Journal of Pharmaceutical Sciences. 107(1):127-138. http://dx.doi.org/10.1016/j.xphs.2017.05.036

246. Alin, J., Setiawan, N., Defrese, M., DiNunzio, J., Lau, H., Lupton, L., Xi, H., Su, Y., Nie, H., Hesse, N., Taylor, L. S., and Marsac, P. J. (2018) A novel approach for measuring room temperature enthalpy of mixing and associated solubility estimation of a drug in a polymer matrix. Polymer. 135(17):50-60. http://dx.doi.org/10.1016/j.polymer.2017.11.056

245. Thorat, A. A., Forny, L., Meunier, V., Taylor, L. S., and Mauer, L. J. (2017) Effects of chloride and sulfate salts on the inhibition or promotion of sucrose crystallization in initially amorphous sucrose-salt blends.. Journal of Agricultural and Food Chemistry. 65(51):11259-11272. http://dx.doi.org/10.1021/acs.jafc.7b04746

244. Tian, B., Gao, W., Tao, X., Tang, X., and Taylor, L. S. (2017) Impact of Polymers on the Melt Crystal Growth Rate of Indomethacin Polymorphs. Crystal Growth and Design. 17(12):6467-6476. http://dx.doi.org/10.1021/acs.cgd.7b01145

243. Mugheirbi, N. A., Marsac, P. J. and Taylor, L. S. (2017) Insights into Water-Induced Phase Separation in Itraconazole-hydroxypropylmethyl cellulose Spin Coated and Spray Dried Dispersions. Molecular Pharmaceutics. 14(12):4387-4402. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00499

242. Hate, S. S., Reutzel-Edens, S. M., and Taylor, L. S. (2017) Absorptive Dissolution Testing of Supersaturating Systems: Impact of Absorptive Sink Conditions on Solution Phase Behavior and Mass Transport. Molecular Pharmaceutics. 14(11):4052-4063. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00740

241. Purohit, H. S., and Taylor, L. S. (2017). Phase Behavior of Ritonavir Amorphous Solid Dispersions During Hydration and Dissolution. Pharmaceutical Research. 34(12):2842-2861. http://dx.doi.org/10.1007/s11095-017-2265-5

240. Arca, H., C., Mosquera-Giraldo, L. I., Dahal, D., Taylor, L. S., and Edgar, K. J. (2017). Multidrug, Anti-HIV Amorphous Solid Dispersions: Nature and Mechanisms of Impacts of Drugs on Each Other’s Solution Concentrations. Molecular Pharmaceutics. 14(11):3617-3627. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00203

239. Mugheirbi, N. A., O’Connel, P., Taylor, L. S., and Tajber, L. (2017) A comparative study on the performance of inert and functionalized spheres coated with solid dispersions made of two structurally related antifungal drugs. Molecular Pharmaceutics. 14(11):3718-3728. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00482

238. Correa-Soto, C., Trasi, N. S., Schmitt, P. D. Su, Y., Liu, Z., Variankaval, N., Marsac, P. J., Simpson, G. J., and Taylor, L. S. (2017). Second Harmonic Generation Microscopy as a Tool for the Early Detection of Crystallization in Spray Dried Dispersions. Journal of Pharmaceutical and Biomedical Analysis. 146:86-95. http://dx.doi.org/10.1016/j.jpba.2017.07.066

237. Xie, T., Gao, W., and Taylor, L. S. (2017). Impact of Eudragit EPO and Hydroxypropyl Methylcellulose on Drug Release Rate, Supersaturation, Precipitation Outcome and Redissolution Rate of Indomethacin Amorphous Solid Dispersions. International Journal of Pharmaceutics. 531(1):313-323. http://dx.doi.org/10.1016/j.ijpharm.2017.08.099

236. Lu, J., Ormes, J. D., Lowinger, M., Mann, A. K. P., Xu, W., Patel, S., Litster, J. D., and Taylor, L. S. (2017). Compositional Effect of Complex Biorelevant Media on the Crystallization Kinetics of an Active Pharmaceutical Ingredient. CrystEngComm. 19:4797-4806. http://dx.doi.org/10.1039/C7CE01128H

235. Saboo, S., and Taylor, L. S. (2017). Water-induced Phase Separation of Miconazole-Poly (Vinylpyrrolidone-Co-Vinyl Acetate) Amorphous Solid Dispersions: Insights with Confocal Fluorescence Microscopy. International Journal of Pharmaceutics. 529(1-2):654-666. http://dx.doi.org/10.1016/j.ijpharm.2017.07.034

234. Trasi, N. S., Purohit, H., and Taylor, L. S. (2017). Evaluation of the Crystallization Tendency of Commercially Available Amorphous Tacrolimus Formulations Exposed to Different Stress Conditions. Pharmaceutical Research. 34(10):2142-2155. http://dx.doi.org/10.1007/s11095-017-2221-4

233. Arioglu-Tuncil, S., Bhardwaj, V., Taylor, L. S. and Mauer, L. J. (2017). The Crystallization Inhibitor Properties of Different Polymers in Thiamine Chloride Hydrochloride Amorphous Solid Dispersions. Food Research International. 99(1):263-374. http://dx.doi.org/10.1016/j.foodres.2017.05.021

232. Indulkar, A. S., Waters, J. E., Mo, H., Gao, Y., Raina, S. A., Zhang, G. G. Z., and Taylor, L. S. (2017). Origin of Nanodroplet Formation upon Dissolution of an Amorphous Solid Dispersion: A Mechanistic Isotope Scrambling Study. Journal of Pharmaceutical Sciences. 106(8):1998-2008. http://dx.doi.org/10.1016/j.xphs.2017.04.015

231. Kalra, A., Tishmack, P., Lubach, J. W., Munson, E., Taylor, L. S., Byrn, S. R., and Li, T. (2017). Impact of Supramolecular Aggregation on the Crystallization Kinetics of Organic Compounds from the Supercooled Liquid State. Molecular Pharmaceutics. 14(6):2126–2137. http://dx.doi.org/10.1021/acs.molpharmaceut.7b00245

230. Lu, J., Ormes, J. D., Lowinger, M., Mann, A. K. P., Xu, W., Patel, S., Litster, J. D., and Taylor, L. S. (2017). Impact of Bile Salts on Solution Crystal Growth Rate and Residual Supersaturation of an Active Pharmaceutical Ingredient. Crystal Growth and Design. 17(6):3528–3537. http://dx.doi.org/10.1021/acs.cgd.7b00464

229. Purohit, H.S., Ormes, J. D., Saboo, S., Su, Y., Lamm, M. S., Mann, A. K. P., and Taylor, L. S. (2017). Insights into Nano- and Micron-scale Phase Separation in Amorphous Solid Dispersions using Fluorescence-based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy. Pharmaceutical Research. 34(7):1364-1377. http://dx.doi.org/10.1007/s11095-017-2145-z

228. Li, N., Gilpin, C. J. and Taylor, L. S. (2017) Understanding the impact of water on the miscibility and microstructure of amorphous solid dispersions – An AFM/LCR and TEM/EDX study. Molecular Pharmaceutics. 14(5):1691–1705. http://dx.doi.org/10.1021/acs.molpharmaceut.6b01151

227. Dong, Y., Mosquera-Giraldo, L.I., Taylor, L.S., and Edgar, K. J. (2017). Tandem Modification of Amphiphilic Cellulose Ethers for Amorphous Solid Dispersion via Olefin Cross-metathesis and Thiol-Michael Addition. Polymer Chemistry. 8:3129-3139. http://dx.doi.org/10.1039/C7PY00228A

226. Icten, E., Purohit, H. S., Wallace, C., Giridhar, A., Taylor, L. S., Nagy, Z. K., Reklaitis, G. V. (2017). Dropwise Additive Manufacturing of Pharmaceutical Products for Amorphous and Self Emulsifying Drug Delivery Systems. International Journal of Pharmaceutics. 524(1-2):424-432. http://dx.doi.org/10.1016/j.ijpharm.2017.04.003.

225. Indulkar, A. S., Mo, H., Gao, Y., Raina, S. A., Zhang, G. G. Z., and Taylor, L. S. (2017). Impact of micellar surfactant on supersaturation and insight into solubilization mechanisms in supersaturated solutions. Pharmaceutical Research. 34(6):1276-1296. http://dx.doi.org/10.1007/s11095-017-2144-0

224. Lu, J., Ormes, J. D., Lowinger, M., Mann, A. K. P., Xu, W., Litster, J. D., and Taylor, L. S. (2017). Maintaining Supersaturation of Active Pharmaceutical Ingredient Solutions with Biologically Relevant Bile Salts. Crystal Growth and Design. 17(5):2782–2791. http://dx.doi.org/10.1021/acs.cgd.7b00237

223. Thorat, A., Marrs, K. N., Ghorab, M. K., Meunier, V., Forny, L., Taylor, L. S, and Mauer, L. J. (2017). Moisture-Mediated Interactions between Amorphous Maltodextrins and Crystalline Fructose. Journal of Food Science. 82(5):1142–1156. http://dx.doi.org/10.1111/1750-3841.13676

222. Lu, J., Ormes, J. D., Lowinger, M., Xu, W., Mitra, A., Mann, A. K. P., Litster, J. D., and Taylor, L. S. (2017). Impact of Endogenous Bile Salts on the Thermodynamics of Supersaturated Active Pharmaceutical Ingredient Solutions. Crystal Growth and Design. 17(3):1264-1275. http://dx.doi.org/10.1021/acs.cgd.6b01664

221. Arca, H.C., Mosquera-Giraldo, L.I., Taylor, L.S., and Edgar, K. J. (2017). Synthesis and characterization of alkyl cellulose ω-carboxyesters for amorphous solid dispersion. Cellulose. 24:609-625. http://dx.doi.org/10.1007/s10570-016-1156-y

220. Nie, H., Xu, W., Taylor, L. S., Marsac, P. J., and Byrn, S. R. (2017). Crystalline solid dispersion-a strategy to slowdown salt disproportionation in solid state formulations during storage and wet granulation. International Journal of Pharmaceutics. 517(1-2):203-215. http://dx.doi.org/10.1016/j.ijpharm.2016.12.014

219. Sato, T. and Taylor, L. S. (2017). Acceleration of the crystal growth rate of low molecular weight organic compounds in supercooled liquids in the presence of polyhydroxybutylate. CrystEngComm. 19:80-87. http://dx.doi.org/10.1039/C6CE02177H

218. Gilley, A. D., Arca, H. C., Nichols, B. L. B., Mosquera-Giraldo, L. I., Taylor, L. S., Edgar, K. J., Neilson, A. P. (2107). Novel Cellulose-Based Amorphous Solid Dispersions Enhance Quercetin Solution Concentrations In Vitro. Carbohydrate Polymers. 157:86-93. http://dx.doi.org/10.1016/j.carbpol.2016.09.067

217. Xie, T., and Taylor, L. S. (2017). Effect of Temperature and Moisture on the Physical Stability of Binary and Ternary Amorphous Solid Dispersions of Celecoxib. Journal of Pharmaceutical Sciences. 106(1):100-110. http://dx.doi.org/10.1016/j.xphs.2016.06.017

216. Trasi, N. S., Purohit, H. S., Wen, H., Sun, D. D., and Lynne S. Taylor (2017). Non-sink dissolution behavior and solubility limit of commercial tacrolimus amorphous formulations. Journal of Pharmaceutical Sciences. 106(1):264-272. http://dx.doi.org/10.1016/j.xphs.2016.09.016

215. Taylor, L. S., Rantanen, J., Paradkar, A., Kawashima, Y., and Zhang, J. (2017). Professor Peter York- A distinguished career in powders, processing and particle design. Journal of Pharmaceutical Sciences. 106(1):2-4. http://dx.doi.org/10.1016/j.xphs.2016.09.006

214. Li, N., Mosquera-Giraldo, L. I., Borca, C. H., Ormes, J. D., Lowinger, M. Higgins, J. D., Slipchenko, L.V., and Taylor, L. S. (2016). A Comparison of the Crystallization Inhibition Properties of Bile Salts. Crystal Growth and Design. 16(12):7286-7300. http://dx.doi.org/10.1021/acs.cgd.6b01470

213. Tian, B., Tang, X., and Taylor, L. S. (2016). Investigating the Correlation between Miscibility and Physical Stability of Amorphous Solid Dispersions Using Fluorescence-based Techniques. Molecular Pharmaceutics. 13(11):3988-4000. http://dx.doi.org/10.1021/acs.molpharmaceut.6b00803

212. Mosquera-Giraldo, L. I., Borca, C. H., Meng, X., Edgar, K. J., Slipchenko, L.V, and Taylor, L. S. (2016). Mechanistic Design of Chemically Diverse Polymers with Applications in Oral Drug Delivery. Biomacromolecules. 17(11):3659-3671. http://dx.doi.org/10.1021/acs.biomac.6b01156

211. Nie, H., Su, Y., Zhang, M., Song, Y., Leone, A., Taylor, L.S., Marsac, P. J., Li, T., and Byrn, S. R. (2016). Solid-State Spectroscopic Investigation of Molecular Interactions between Clofazimine and Hypromellose Phthalate in Amorphous Solid Dispersions. Molecular Pharmaceutics. 13(11):3964-3975. http://dx.doi.org/10.1021/acs.molpharmaceut.6b00740

210. Lu, M. and Taylor, L. S. (2016). Vemurafenib: A Tetramorphic System Displaying Concomitant Crystallization from the Supercooled Liquid. Crystal Growth and Design. 16(10):6033-6042. http://dx.doi.org/10.1021/acs.cgd.6b01066

209. Nie, H., Xu, W., Ren, J., Taylor, L. S., Marsac, P. J., John, C. T., and Byrn, S. R. (2016). Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. Molecular Pharmaceutics. 13(10):3541-3552. http://dx.doi.org/10.1021/acs.molpharmaceut.6b00630

208. Dong, Y., Mosquera-Giraldo, L. I, Troutman, J., Skogstad, B., Taylor, L. S. and Edgar, K. J. (2016). Amphiphilic Hydroxyalkyl Cellulose Derivatives for Amorphous Solid Dispersion Prepared by Olefin Cross-Metathesis. Polymer Chemistry. 7:4953-4963.http://dx.doi.org/10.1039/C6PY00960C

207. Sun, D. D., Wen, H. and Taylor, L. S. (2016). Non-sink dissolution conditions for predicting product quality and in vivo performance of supersaturating drug delivery systems. Journal of Pharmaceutical Sciences.105(9):2477-2488. http://dx.doi.org/10.1016/j.xphs.2016.03.024

206. Indulkar, A. S., Gao, Y., Raina, S. A., Zhang, G. G. Z., and Taylor, L. S. (2016). Exploiting the phenomenon of liquid-liquid phase separation for enhanced and sustained membrane transport of a poorly water soluble drug. Molecular Pharmaceutics. 13(6):2059-2069. http://dx.doi.org/10.1021/acs.molpharmaceut.6b00202

205. Schram, C. J., Smyth, R. J., Taylor, L. S. and Beaudoin, S. P. (2016). Understanding Crystal Growth Kinetics in the Absence and Presence of a Polymer Using a Rotating Disk Apparatus. Crystal Growth and Design. 16(5):2640-2645. http://dx.doi.org/10.1021/acs.cgd.5b01729

204. Li, N., Ormes, J. D. and Taylor, L. S. (2016). Leaching of Lopinavir Amorphous Solid Dispersions in Acidic Media. Pharmaceutical Research. 33(7):1723-1735. http://dx.doi.org/10.1007/s11095-016-1913-5

203. Taylor, L. S. and Zhang, G. G. Z. (2016) Physical Chemistry of Supersaturated Solutions and Implications for Oral Absorption. Advanced Drug Delivery Reviews. 101:122-142. http://dx.doi.org/10.1016/j.addr.2016.03.006

202. Alhalaweh, A., Bergström, C. A. S. and Taylor, L. S. (2016). Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations. Journal of Controlled Release.229:172-182. http://dx.doi.org/10.1016/j.jconrel.2016.03.028

201. Jackson, M. J., Kestur, U. S., Hussain, M. A., and Taylor, L. S. (2016). Characterization of Highly Supersaturated Danazol Solutions – Impact of Polymers on Solution Properties and Phase Transitions. Pharmaceutical Research. 33(5):1276-1288. http://dx.doi.org/10.1007/s11095-016-1871-y

200. Li., N. and Taylor, L. S. (2016). Nanoscale Infrared, Thermal, and Mechanical Characterization of Telaprevir-Polymer Miscibility in Amorphous Solid Dispersions Prepared by Solvent Evaporation. Molecular Pharmaceutics. 13(3):1123-1136. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00925

199. Schram, C. J., Beaudoin, S. P. and Taylor, L. S. (2016). Polymer Inhibition of Crystal Growth by Surface Poisoning. Crystal Growth and Design. 16(4):2094-2103. http://dx.doi.org/10.1021/acs.cgd.5b01779

198. Xie, T., and Taylor, L. S. (2016). Improved Release of Celexocib from High Drug Loading Amorphous Solid Dispersions Formulated with Polyacrylic Acid and Cellulose Derivatives. Molecular Pharmaceutics.13(3):873-884. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00798

197. Almeida e Sousa, L., Reutzel-Edens, S. M., Stephenson, G. A. and Taylor, L. S. (2016). Supersaturation Potential of Salt, Co-Crystal and Amorphous Forms of a Model Weak Base. Crystal Growth and Design. 16(2):737-748. http://dx.doi.org/10.1021/acs.cgd.5b01341

196. Dong, Y., Mosquera-Giraldo, L. I., Taylor, L. S. and Edgar, K. J. (2016). Design of Functionalized Cellulose Ethers for Amorphous Solid Dispersion via Olefin Cross-Metathesis. Biomacromolecules. 17(2):454-465. http://dx.doi.org/10.1021/acs.biomac.5b01336

195. Jackson, M. J., Kestur, U. S., Hussain, M. A., and Taylor, L. S. (2016). Dissolution of Danazol Amorphous Solid Dispersions: Supersaturation and Phase Behavior as a Function of Drug Loading and Polymer Type. Molecular Pharmaceutics. 13(1):223-231. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00652

194. Xie, T., and Taylor, L. S. (2016). Dissolution Performance of High Drug Loading Celecoxib Amorphous Solid Dispersions Formulated with Polymer Combinations. Pharmaceutical Research. 33(3):739-750. http://dx.doi.org/10.1007/s11095-015-1823-y

193. Nie, H., Liu, Z., Marks, B. C., Taylor, L. S., Byrn, S. R. and Marsac, P. J. (2016). Analytical Approaches to Investigate Salt Disproportionation in Tablet Matrices by Raman Spectroscopy and Raman Mapping. Journal of Pharmaceutical and Biomedical Analysis. 118:328-337. http://dx.doi.org/10.1016/j.jpba.2015.10.024

192. Allan, M., Taylor, L. S. and Mauer, L. J. (2016). Common-Ion Effects on the Deliquescence Lowering of Crystalline Ingredient Blends. Food Chemistry. 195:2-10. http://dx.doi.org/10.1016/j.foodchem.2015.04.063

191. Li, N., Taylor, L. S. and Mauer, L. J. (2016). Heat Transport Model for the Deliquescence Kinetics of Crystalline Ingredients and Mixtures. Journal of Food Engineering. 169:298-308. http://dx.doi.org/10.1016/j.jfoodeng.2015.08.013

190. Purohit, H. S. and Taylor, L. S. (2015). Miscibility of Itraconazole-Hydroxypropyl Methylcellulose Blends- Insights with High Resolution Analytical Methodologies. Molecular Pharmaceutics. 12(12):4542-4542. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00761

189. Trasi, N. and Taylor, L. S. (2015). Dissolution Performance of Binary Amorphous Drug Combinations – Impact of a Second Drug on the Maximum Achievable Supersaturation. International Journal of Pharmaceutics. 496(2):282-290. http://dx.doi.org/10.1016/j.ijpharm.2015.10.026

188. Schram, C. J., Taylor, L. S. and Beaudoin, S. P. (2015). Influence of Polymers on the Crystal Growth Rate of Felodipine – Correlating Adsorbed Polymer Surface Coverage to Solution Crystal Growth Inhibition. Langmuir. 31(41):11279-11287. http://dx.doi.org/10.1021/acs.langmuir.5b02486

187. Liu, H., Taylor, L. S. and Edgar, K. E. (2015). The Role of Polymers in Oral Bioavailability Enhancement; A Review. Polymer. 77:399-415. http://dx.doi.org/10.1016/j.polymer.2015.09.026

186. Raina, S. A., Alonzo, D. E., Zhang, G. G. Z., Gao, Y. and Taylor, L. S. (2015). Using Environment-Sensitive Fluorescent Probes to Characterize Liquid-Liquid Phase Separation in Supersaturated Solutions of Poorly Water Soluble Compounds. Pharmaceutical Research. 32(11):3660-3673. http://dx.doi.org/10.1007/s11095-015-1725-z

185. Schmitt, P. D., Trasi, N. S., Taylor, L. S. and Simpson, G. J. Finding the Needle in the Haystack – Characterization of Trace Crystallinity in a Commercial Formulation of Paclitaxel Protein-Bound Particles by Raman Spectroscopy Enabled by Second Harmonic Generation Microscopy. (2015) Molecular Pharmaceutics. 12(7):2378-2383. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00065

184. Sato, T. and Taylor, L. S. (2015). Chiral Discrimination by a Cellulose Polymer: Differential Crystallization Inhibition of Enantiomers in Amorphous Dispersions. CrystEngComm. 17:5046-5053. http://dx.doi.org/10.1039/C5CE00810G

183. Trasi, N. S. and Taylor, L. S. (2015). Thermodynamics of Highly Supersaturated Aqueous Solutions of Poorly Water Soluble Drugs – Impact of a Second Drug on the Solution Phase Behavior and Implications for Combination Products. Journal of Pharmaceutical Sciences. 104(8):2583-2593. http://dx.doi.org/10.1002/jps.24528

182. Raina, S. A., Zhang, G. G. Z., Alonzo, D. E., Wu, J., Zhu, D., Catron, N. D., Gao, Y. and Taylor, L. S. (2015). Impact of Solubilizing Additives on Supersaturation and Membrane Transport of Drugs. Pharmaceutical Research. 32(10):3350-3364. http://dx.doi.org/10.1007/s11095-015-1712-4

181. Christina, B., Taylor, L. S., and Mauer, L. J. (2015). Physical stability of L-ascorbic acid amorphous solid dispersions in different polymers: a study of polymer crystallization inhibitor properties. Food Research International. 76(3):867-877. http://dx.doi.org/10.1016/j.foodres.2015.08.009

180. Nie, H., Mo, H., Zhang, M., Song, Y., Fang, K., Taylor, L. S. Li, T. and. Byrn, S. R. (2015). Investigating the interaction pattern and structural elements of a drug-polymer complex at the molecular level. Molecular Pharmaceutics. 12(7)2459-2468. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00162

179. Indulkar, A., Box, K. J., Taylor, R., Ruiz, R., and Taylor, L. S. (2015). pH-Dependent Liquid-Liquid Phase Separation of Highly Supersaturated Solutions of Weakly Basic Drugs. Molecular Pharmaceutics. 12(7):2365-2377. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00056

178. Wegiel, L.A., Mosquera-Giraldo L.,Mauer, L.J. , Edgar, K.J., and Taylor, L.S. (2015) Phase Behavior of Resveratrol Solid Dispersions Upon Addition to Aqueous Media. Pharmaceutical Research. 32(10):3324-3337. http://dx.doi.org/10.1007/s11095-015-1709-z

177. Chen, J., Mosquera-Giraldo L., Ormes, J. D., Higgins, J. D. and Taylor, L. S. (2015). Bile Salts as Crystallization Inhibitors of Supersaturated Solutions of Poorly Water-Soluble Compounds. Crystal Growth and Design. 15(6):2593-2597. http://dx.doi.org/10.1021/acs.cgd.5b00392

176. Hsieh, Y-L., Merritt, J. M.; Yu, W., and Taylor, L. S. Salt Stability – The Effect of pHmax on Salt to Free Base Conversion. (2015). Pharmaceutical Research. 32(9):3110-3118. http://dx.doi.org/10.1007/s11095-015-1691-5

175. Purohit, H. S. and Taylor, L. S. Phase Separation Kinetics in Amorphous Solid Dispersions Upon Exposure to Water. (2015) Molecular Pharmaceutics. 12(5):1623-1635. http://dx.doi.org/10.1021/acs.molpharmaceut.5b00041

174. Raina, S. A., Van Eerdenbrugh, B., Alonzo, D. E., Mo, H., Zhang, G. G. Z., Gao, Y. and Taylor, L. S. (2015). Trends in the Precipitation and Crystallization Behavior of Supersaturated Aqueous Solutions of Poorly Water Soluble Drugs Assessed using Synchrotron Radiation. Journal of Pharmaceutical Sciences. 104(6):1981-1992. http://dx.doi.org/10.1002/jps.24423

173. Içten, E., Giridhar, A., Taylor, L. S., Nagy, Z. K., Reklaitis, G. V. (2015). Dropwise Additive Manufacturing of Pharmaceutical Products for Melt-Based Dosage Forms. Journal of Pharmaceutical Sciences. 104(5):1641-1649. http://dx.doi.org/10.1002/jps.24367

172. Toth, S., Schmitt, P. D., Snyder, G. R., Trasi, N. S., George, I. A., Taylor, L. S. and Simpson, G. J. (2015) Ab Initio Prediction of the Diversity of Second Harmonic Generation from Pharmaceutically Relevant Materials. Crystal Growth and Design. 15(2):581-586. http://dx.doi.org/10.1021/acs.cgd.5b00020

171. Chen, J., Ormes, J. D., Higgins, J. D. and Taylor, L. S. (2015) Impact of Surfactants on the Crystallization of Aqueous Suspensions of Celecoxib Amorphous Solid Dispersion Spray Dried Particles. Molecular Pharmaceutics. 12(2):533-541. http://dx.doi.org/10.1021/mp5006245

170. Mosquera-Giraldo L., and Taylor, L. S. Glass-Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Telaprevir. (2015) Molecular Pharmaceutics. 12(2):496-501. http://dx.doi.org/10.1021/mp500573z

169. Trasi, N. S., Abbou-Oucherif, K., Litster, J. D. and Taylor, L. S. (2015) Evaluating the Influence of Polymers on Nucleation and Growth in Supersaturated Solutions of Acetaminophen. CrystEngComm. 17:1242-1248. http://dx.doi.org/10.1039/C4CE02179G

168. Almeida e Sousa, L., Reutzel-Edens, S. M., Stephenson, G. A. and Taylor, L. S. (2015). Assessment of the Amorphous “Solubility” of a Group of Diverse Drugs Using New Experimental and Theoretical Approaches. Molecular Pharmaceutics. 12(2):484-495. http://dx.doi.org/10.1021/mp500571m

167. Schram, C. J., Beaudoin, S. P. and Taylor, L. S. (2015). Impact of Polymer Conformation on the Crystal Growth Inhibition of a Poorly Water Soluble Drug in Aqueous Solution. Langmuir. 31(1):171-179. http://dx.doi.org/10.1021/la503644m

166. Hsu, H-Y, Adigun, O. O., Taylor, L. S., Murad, S. and Harris, M. T. (2015). Impact of Surface Chemistry on Crystallization of Acetaminophen. Chemical Engineering Science. 126:1-9. http://dx.doi.org/10.1016/j.ces.2014.10.046

165. Lipasek, R.A., Li, N., Taylor, L. S. and Mauer, L. J. (2015) Effect of temperature and initial moisture content on the chemical stability and color change of various forms of vitamin C. International Journal of Food Properties. 18(4):862-879. http://dx.doi.org/10.1080/10942912.2013.805770

164. Hsieh, Y-L., and Taylor, L. S. (2015). Salt Stability - Effect of Particle Size, Relative Humidity, Temperature and Composition on Salt to Free Base Conversion. Pharmaceutical Research. 32(2):549-561. http://dx.doi.org/10.1007/s11095-014-1484-2

163. Raina, S. A., Alonzo, D. E., Zhang, G. G. Z., Gao, Y. and Taylor, L. S. (2014). Impact of Polymers on the Crystallization and Phase Transition Kinetics of Amorphous Nifedipine during Dissolution in Aqueous Media. Molecular Pharmaceutics. 11(10):3565-3576. http://dx.doi.org/10.1021/mp500333v

162. Jackson, M. J., Toth S. J., Kestur, U. S., Huang, J. Qian, F., Hussain, M. A. Simpson, G. J., and Taylor, L. S. (2014). Impact of Polymers on the Precipitation Behavior of Highly Supersaturated Aqueous Danazol Solutions. Molecular Pharmaceutics. 11(9):3027-3038. http://dx.doi.org/10.1021/mp500201s

161. Trasi, N., Baird, J. A. and Kestur, U. S. and Taylor, L. S. (2014). Factors Influencing Crystal Growth Rates from Undercooled Liquids of Pharmaceutical Compounds. Journal of Physical Chemistry B. 118(33):9974-9982. http://dx.doi.org/10.1021/jp504450h

160. Marks, J., Wegiel, L. A., Taylor, L. S. and Edgar, K. J. (2014). Pairwise Polymer Blends for Oral Drug Delivery. Journal of Pharmaceutical Sciences. 103(9):2871-2883. http://dx.doi.org/10.1002/jps.23991

159. Taylor, L. S. and Hancock, B. C. (2014) George Zografi and the Science of Solids and Surfaces. Journal of Pharmaceutical Sciences. 103(9):2592-2594. http://dx.doi.org/10.1002/jps.24000

158. Trasi, N. and Taylor, L. S. (2014). Nucleation and Crystal Growth of Amorphous Nilutamide –Unusual Low Temperature Behavior. CrystEngComm. 16:7186-7195. http://dx.doi.org/10.1039/C4CE00118D

157. Hsieh, Y-L., Box, K. and Taylor, L. S. (2014). Assessing the Impact of Polymers on the pH-Induced Precipitation Behavior of Poorly Water Soluble Compounds using Synchrotron Wide Angle X-Ray Scattering. Journal of Pharmaceutical Sciences. 103(9):2724-2735. http://dx.doi.org/10.1002/jps.23890

156. Raina, S. A., Zhang, G. G. Z., Alonzo, D. E., Wu, J., Zhu, D., Catron, N. D., Gao, Y. and Taylor, L. S. (2014). Enhancements and Limits in Drug Membrane Transport Using Supersaturated Solutions of Poorly Water Soluble Drugs. Journal of Pharmaceutical Sciences. 103(9):2736-2748. http://dx.doi.org/10.1002/jps.23826

155. Li, N., Taylor, L. S. and Mauer, L. J. (2014). The Physical and Chemical Stability of Amorphous (-)-Epi-Gallocatechin Gallate: Effects of Water Vapor Sorption and Storage Temperature. Food Research International. 58:112-123. http://dx.doi.org/10.1016/j.foodres.2014.01.043

154. Liu, H., Ilevbare, G. A., Cherniawskia, B. P., Ritchie, E. T., Taylor, L. S. and Edgar, K. J. (2014). Synthesis and Structure-property Evaluation of Cellulose ω-carboxyesters for Amorphous Solid Dispersions. Carbohydrate Polymers. 100:116-125. http://dx.doi.org/10.1016/j.carbpol.2012.11.049

153. Hirshfield, L., Giridhar, A., Taylor, L. S., Harris, M. T., Reklaitis, G. V. (2014). Dropwise Additive Manufacturing of Pharmaceutical Products for Solvent-Based Dosage Forms. Journal of Pharmaceutical Sciences. 103(2):496-506. http://dx.doi.org/10.1002/jps.23803

152. Mosquera-Giraldo L., Trasi, N. S., and Taylor, L. S. (2014) Impact of Surfactants on the Crystal Growth of Amorphous Celecoxib. International Journal of Pharmaceutics. 461(1-2):251-257. http://dx.doi.org/10.1016/j.ijpharm.2013.11.057

151. Hsieh, Y-L., Yu, W., Xiang, Y., Pan, W., Waterman, K. C., Shalaev, E. Y., Shamblin, S. L. and Taylor, L. S. (2014). Impact of Sertraline Salt Form on the Oxidative Stability in Powder Blends. International Journal of Pharmaceutics. 461(1-2):322-330. http://dx.doi.org/10.1016/j.ijpharm.2013.11.054

150. Van Eerdenbrugh, B., Raina, S. A., Hsieh, Y-L., Augustijns, P. and Taylor, L. S. (2014). Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments. Pharmaceutical Research. 31(4):969-982. http://dx.doi.org/10.1007/s11095-013-1216-z

149. Wegiel, L.A., Mauer, L.J. , Edgar, K.J., and Taylor, L.S. (2014). Curcumin Amorphous Solid Dispersions: The Influence of Intra and Intermolecular Bonding on Physical Stability. Pharmaceutical Development and Technology. 19(8):976-986. http://dx.doi.org/10.3109/10837450.2013.846374

148. Wegiel, L.A., Mauer, L.J. , Edgar, K.J., and Taylor, L.S. (2014). Mid-Infrared Spectroscopy as a Polymer Selection Tool for Formulating Amorphous Solid Dispersions. Journal of Pharmacy and Pharmacology. 66(2):244-255. http://dx.doi.org/10.1111/jphp.12079

147. Ghorab, M.K, Marrs, K, Taylor, L. S. and Mauer, L. J. (2014) Water-Solid Interactions between Amorphous Maltodextrin and Crystalline Sodium Chloride. Food Chemistry. 144:26-35. http://dx.doi.org/10.1016/j.foodchem.2013.02.123

146. Ghorab, M.K, Toth, S J., Simpson, G. J., Mauer, L. J. and Taylor, L. S. (2014) Water-Solid Interactions in Amorphous Maltodextrin-Crystalline Sucrose Binary Mixtures. Pharmaceutical Development and Technology. 19(2):247-256. http://dx.doi.org/10.3109/10837450.2013.775157

145. Harrison A. J., Bilgili, E. A., Beaudoin, S. P. and Taylor, L. S. (2013) Atomic force microscope infrared spectroscopy of griseofulvin nanocrystals. Analytical Chemistry. 85(23):11449-11455. http://dx.doi.org/10.1021/ac4025889

144. Pereira, J. M., Mejia-Ariza, R., Ilevbare, G. A. McGettigan, H. E., Sriranganathan, N., Taylor, L. S., Davis, R. M. and Edgar, K. J. (2013) Interplay of Degradation, Dissolution and Stabilization of Clarithromycin and its Amorphous Solid Dispersions. Molecular Pharmaceutics. 10(12):4640-4653. http://dx.doi.org/10.1021/mp400441d

143. Kestur, U. S. and Taylor, L. S. (2013). Evaluation of the Crystal Growth Rate of Felodipine Polymorphs in the Presence and Absence of Additives as a Function of Temperature. Crystal Growth and Design. 13(10):4349-4354 http://dx.doi.org/10.1021/cg400708p

142. Ilevbare, G. A., Liu, H., Pereira, J., Edgar, K. J., Taylor, L.S. (2013). Influence of Additives on the Properties of Nanodroplets Formed in Highly Supersaturated Aqueous Solutions of Ritonavir. Molecular Pharmaceutics. 10(9):3392-3403. http://dx.doi.org/10.1021/mp400228x

141. Lipasek, R.A., Li, N., Schmidt, S. J. Taylor, L. S. and Mauer, L. J. (2013). Effect of Temperature on the Deliquescence Properties of Food Ingredients and Blends. Journal of Agriculture and Food Chemistry. 61(38):9241-2950. http://dx.doi.org/10.1021/jf402585t

140. Ilevbare, G. A. Liu, H, Edgar, K. J., Taylor, L.S. (2013). Impact of Polymers on the Crystal Growth Rate of Structurally Diverse Compounds from Aqueous Solution. Molecular Pharmaceutics. 10(6):2381–2393. http://dx.doi.org/10.1021/mp400029v

139. Ilevbare, G. A. and Taylor, L. S. (2013). Liquid-Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Poorly-Water Soluble Drugs – Implications for Solubility Enhancing Formulations. Crystal Growth and Design. 13(4):1497-1509. http://dx.doi.org/10.1021/cg301679h

138. Li, B., Konecke, S., Wegiel, L.A., Taylor, L.S. and Edgar, K.J. (2013) Both Solubility and Chemical Stability of Curcumin are Enhanced by Solid Dispersion in Cellulose Derivative Matrices. Cellulose. 98: 1108-1116. http://dx.doi.org/10.1016/j.carbpol.2013.07.017

137. Li, B., Liu, H., Amin, M., Wegiel, L.A., Taylor, L.S. and Edgar, K.J. (2013).Enhancement of Naringenin Solution Concentration by Solid Dispersion in Cellulose Derivative Matrices. Cellulose. 20(4): 2137-2149. http://dx.doi.org/10.1007/s10570-013-9970-y

136. Li, B., Wegiel, L.A., Taylor, L.S. and Edgar, K.J. (2013). Stability and Solubility Enhancement of Resveratrol in Spray Dried Solid Dispersion with Cellulose Derivative Matrices. Cellulose. 20(3):1249-1260. http://dx.doi.org/10.1007/s10570-013-9889-3

135. Maltaş, D. C., Kwok, K., Wang, P., Taylor, L. S. and Ben-Amotz, D. (2013) Rapid Classification of Pharmaceutical Ingredients with Raman Spectroscopy Using Compressive Detection Strategy with PLS-DA Multivariate Filters. Journal of Pharmaceutical and Biomedical Analysis.80:63-68. http://dx.doi.org/10.1016/j.jpba.2013.02.029

134. Zhou, Q., Toth, S J., Simpson, G. J., Hsu H-Y., Taylor L. S., Harris, M. T., (2013) Crystallization and Dissolution Behavior of Naproxen/Polyethylene Glycol Solid Dispersions. Journal of Physical Chemistry. 117(5):1494-1500. http://dx.doi.org/10.1021/jp3106716

133. Ilevbare, G. A., Liu, H, Edgar, K. J., Taylor, L.S. (2013). Maintaining Supersaturation in Aqueous Drug Solutions - Impact of Different Polymers on Induction Times. Crystal Growth and Design. 13(2):740-751. http://dx.doi.org/10.1021/cg301447d

132. Kestur, U. S., Ivanisevic, I, Alonzo, D. E. and Taylor, L. S. (2013). Influence of Particle Size on the Crystallization Kinetics of Amorphous Felodipine Powders. Powder Technology.236:197–204. http://dx.doi.org/10.1016/j.powtec.2012.02.010

131. Li, N., Taylor, L. S. Ferruzzi, M. G. and Mauer, L. J. (2013). Color and Chemical Stability of Tea Polyphenol (-)-Epigallocatechin-3-gallate in Solution and Solid States. Food Research International. http://dx.doi.org/10.1016/j.foodres.2012.11.019

130. Li, B., Konecke, S., Harich, K., Wegiel, L.A., Taylor, L.S. and Edgar, K.J. (2013). Solid Dispersion of Quercetin in Cellulose Derivative or PVP Matrix Influences both Solubility and Stability. Carbohydrate Polymers. 92(2):2033-2040. http://dx.doi.org/10.1016/j.carbpol.2012.11.073

129. Hsu, H-Y, Toth, S. J., Simpson, G. J., Taylor, L. S., Harris, M. T. (2013) Effect of Substrates on Naproxen\Polyvinylpyrrolidone Solid Dispersions Formed via the Drop Printing Technique. Journal of Pharmaceutical Sciences. 102(2):638-648. http://dx.doi.org/10.1002/jps.23397

128. Abbou Oucherif, K. Raina, S., Taylor, L. S. and Litster, J. (2013) Quantitative Analysis of the Inhibitory Effect of HPMC on Felodipine Crystallization Kinetics Using Population Balance Modeling. CrystEngComm. 15:2197-2205. http://dx.doi.org/10.1039/c2ce26490k

127. Christensen, N. P. A., Van Eerdenbrugh, B., Kwok, K., Taylor, L. S., Bond, A. D. Rades, T., Rantanen, J., Cornett, C. (2013) Rapid Insight into Heating-induced Phase Transformations in the Solid-state of the Calcium Salt of Atorvastatin using Multivariate Data Analysis.Pharmaceutical Research. 30(3):826-835. http://dx.doi.org/10.1007/s11095-012-0923-1

126. Li, B., Harich, K., Wegiel, L.A., Taylor, L.S. and Edgar, K.J. (2013) Stability and Solubility Enhancement of Ellagic Acid in Cellulose Ester Solid Dispersions. Carbohydrate Polymers.92:1443-1450. http://dx.doi.org/10.1016/j.carbpol.2012.10.051

125. Baird, J.A., Thomas, L.C., Aubuchon, S.R. and Taylor, L. S. (2013). Evaluating the Non-isothermal Crystallization Behavior of Organic Molecules from the Undercooled Melt State using Rapid Heat/Cool Calorimetry. CrystEngComm. 15(1):111-119. http://dx.doi.org/10.1039/C2CE26448J

124. Wegiel, L.A., Mauer, L.J. , Edgar, K.J., and Taylor, L.S.(2013) Crystallization of Amorphous Solid Dispersions of Resveratrol during Preparation and Storage – Impact of Different Polymers. Journal of Pharmaceutical Sciences. 102(1):171-184. http://dx.doi.org/10.1002/jps.23358

123. Back, K. R., Davey, R.J., Grecu, T., Hunter, C. A. and Taylor, L. S. (2012) Molecular Conformation and Crystallisation – The Case of Ethenzamide. Crystal Growth and Design. 12(12):6110-6117. http://dx.doi.org/10.1021/cg301244x

122. Ilevbare, G. A., Liu, H., Edgar, K. J., Taylor, L.S. (2012). The Effect of Binary Additive Combinations on Solution Crystal Growth of the Poorly Water-Soluble Drug, Ritonavir. Crystal Growth and Design.12(12):6050-6060. http://dx.doi.org/10.1021/cg301169t

121. Stoklosa, A. M., Lipasek, R. Taylor, L. S. and Mauer, L. J. (2012) Effects of Storage Conditions, Formulation, and Particle Size on Moisture Sorption and Flowability of Powders: a Study of Deliquescent Ingredient Blends. Food Research International. 49: 783-791. http://dx.doi.org/10.1016/j.foodres.2012.09.034

120. Kestur, U. S., Wanapun, D., Toth, S.J. , Wegiel, L. A., Simpson, G. J. and Taylor, L. S. (2012) Nonlinear Optical Imaging for Sensitive Detection of Crystals in Bulk Amorphous Powders. Journal of Pharmaceutical Sciences. 101(11):4201–4213. http://dx.doi.org/10.1002/jps.23280

119. Ilevbare, G. A. Liu, H, Edgar, K. J., Taylor, L.S. (2012). Inhibition of Solution Crystal Growth of Ritonavir by Cellulose Polymers – Factors Influencing Polymer Effectiveness. CrystEngComm. 14:6503-651. http://dx.doi.org/10.1039/C2CE25515D

118. Christensen, N. P. A., Rantanen, J., Cornett, C., and Taylor, L. S. (2012) Physical Stability of the Calcium Salt of Atorvastatin in the Presence of Acidic Excipients. European Journal of Pharmaceutics and Biopharmaceutics. 82:410-416. http://dx.doi.org/10.1016/j.ejpb.2012.07.003

117. Toth, S.J., Madden, J. T., and Taylor, L. S., Marsac, P.J., and Simpson, G. J. (2012) Selective Imaging of Active Pharmaceutical Ingredients in Powdered Blends with Common Excipients Utilizing Two-Photon Excited Ultraviolet-Fluorescence and Ultraviolet-Second Order Nonlinear Optical Imaging of Chiral Crystals. Analytical Chemistry. 84(14):5859-5875. http://dx.doi.org/10.1021/ac300917t

116. Trasi, N. S. and Taylor, L. S. (2012). Effect of Polymers on Nucleation and Crystal Growth of Amorphous Acetaminophen. CrystEngComm. 14(16):5188-5197. http://dx.doi.org/10.1039/C2CE25374G

115. Hsieh, Y-L., Ilevbare, G.A., Van Eerdenbrugh, B., Box, K., Sanchez-Felix, M. V. and Taylor, L. S. (2012) pH-Induced Precipitation Behavior of Weakly Basic Compounds – Determination of Extent and Duration of Supersaturation using Potentiometric Titration and Correlation to Solid State Properties. Pharmaceutical Research. 29(10):2738-2753. http://dx.doi.org/10.1007/s11095-012-0759-8

114. Trasi, N. S., and Taylor, L. S. (2012). Effect of Additives on Crystal Growth and Nucleation of Amorphous Flutamide. Crystal Growth and Design.12(6):3221-3230. http://dx.doi.org/10.1021/cg300370q

113. Ilevbare, G. A., Liu, H., Edgar, K. J., Taylor, L.S. (2012) Understanding Polymer Properties Important for Crystal Growth Inhibition – Impact of Chemically Diverse Polymers on Solution Crystal Growth of Ritonavir. Crystal Growth and Design. 12(6):3133-3143. http://dx.doi.org/10.1021/cg300325p

112. Van Eerdenbrugh, B., Lo, M., Kjoller, K., Marcott, C. and Taylor, L.S. (2012) Nanoscale Mid-Infrared Evaluation of the Miscibility Behavior of Blends of Dextran or Maltodextrin with Poly(vinylpyrrolidone). Molecular Pharmaceutics. 9(5):1459-1469. http://dx.doi.org/10.1021/mp300059z

111. Kwok, K. and Taylor, L. S. (2012). Analysis of Counterfeit Cialis® Tablets Using Raman Microscopy and Multivariate Curve Resolution. Journal of Pharmaceutical and Biomedical Analysis.66:126-135. http://dx.doi.org/10.1016/j.jpba.2012.03.026

110. Kwok, K. and Taylor, L. S. (2012). Analysis of the Packaging Enclosing a Counterfeit Pharmaceutical Tablet using Raman Microscopy and Two-dimensional Correlation Spectroscopy. Vibrational Spectroscopy. 161:176-182. http://dx.doi.org/10.1016/j.vibspec.2012.02.018

109. Van Eerdenbrugh, B., Lo, M., Kjoller, K., Marcott, C. and Taylor, L.S. (2012) Nanoscale Mid-Infrared Imaging of Phase Separation in a Drug-Polymer Blend. Journal of Pharmaceutical Sciences. 101(6):2066-2073. http://dx.doi.org/10.1002/jps.23099

108. Li, N., Taylor, L. S. Ferruzzi, M. G. and Mauer, L. J. (2012) Kinetic study of catechin stability: Effects of pH,concentration, and temperature. Journal of Agricultural and Food Chemistry. 60(51)12531-12539. http://dx.doi.org/10.1021/jf304116s

107. Zhou, Q. Harris, M. T., and Taylor L. S. (2012) Modification of Crystallization Behavior in Drug/Polyethylene Glycol Solid Dispersions. Molecular Pharmaceutics. 9(3):546-553. http://dx.doi.org/10.1021/mp200546p

106. Alonzo, D.E., Raina, S., Zhou, D.,Gao, Y., Zhang, G.G.Z., and Taylor, L.S. (2012). Characterizing the Impact of Hydroxypropylmethyl Cellulose on the Growth and Nucleation Kinetics of Felodipine from Supersaturated Solutions. Crystal Growth and Design. 12(3):1538-1547. http://dx.doi.org/10.1021/cg201590j.

105. Van Eerdenbrugh, B. and Taylor, L. S. (2012) . Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone). Pharmaceutical Research. 29(10):2754-2765. http://dx.doi.org/10.1007/s11095-012-0689-5.

104. Weber, R. J. K., Benmore, C. J., Tumber, S. J., Tailor, A.N., Rey, C.A., Taylor, L. S. and Byrn, S. R. (2012) Acoustic Levitation: Recent Developments and Emerging Opportunities in Biomaterials Research. Eur. Biophys. J. 41(4):397-403. http://dx.doi.org/10.1007/s00249-011-0767-3

103. Baird, J. A. and Taylor, L.S. (2012) Evaluation of Amorphous Solid Dispersion Properties using Thermal Analytical Techniques. Advanced Drug Delivery Reviews. 64(5):396-421. http://dx.doi.org/10.1016/j.addr.2011.07.009

102. Trasi, N. S., Fanwick, P. E. and Taylor, L.S. (2012). Nilutamide. Acta Crystallographica E.68(3):o591. http://dx.doi.org/10.1107/S1600536812003728

101. Baird, J. A., Santiago-Quinonez, D., Rinaldi, C. and Taylor, L. S. (2012). Role of Viscosity in Influencing the Glass-forming Ability of Organic Molecules from the Undercooled Melt State. Pharm. Res. 29(1):271-284. http://dx.doi.org/10.1007/s11095-011-0540-4

100. Lipasek, R. A., Ortiz, J. C., Taylor, L. S. and Mauer, L. J. (2012) Effects of Anticaking Agents and Storage Conditions on the Moisture Sorption, Caking, and Flowability of Deliquescent Ingredients. Food Research International. 45(1):369-380. http://dx.doi.org/10.1016/j.foodres.2011.10.037

99. Rumondor, A.C.F, Wikström, H., Van Eerdenbrugh, B. and Taylor, L. S. (2011). Understanding the Tendency of Amorphous Solid Dispersions to Undergo Amorphous–Amorphous Phase Separation in the Presence of Absorbed Moisture. AAPSPharmSciTech. 12(4):1209-1219. http://dx.doi.org/10.1208/s12249-011-9686-y

98. Kestur, U.S., Van Eerdenbrugh, B. and Taylor, L.S. (2011) Influence of polymer chemistry on crystal growth inhibition of two chemically diverse organic molecules. CrystEngComm. 13:6712-6718 http://dx.doi.org/10.1039/c1ce05822c

97. Van Eerdenbrugh, B., and Taylor L. S. (2011). An Ab Initio Polymer Selection Methodology to Prevent Crystallization in Amorphous Solid Dispersions by Application of Crystal Engineering Principles. CrystEngComm. 13:6171-6178. http://dx.doi.org/10.1039/c1ce05183k

96. Lipasek, R. A., Taylor, L.S., and Mauer, L. J. (2011) Effects of Anticaking Agents and Relative Humidity on the Physical and Chemical Stability of Powdered Vitamin C. Journal of Food Science. 176(7):C1062-C1074 http://dx.doi.org/10.1111/j.1750-3841.2011.02333.x

95. Alonzo, D.E., Gao, Y.,Zhou, D., Mo, H., Zhang, G.G.Z., and Taylor, L.S. (2011) Dissolution and Precipitation Behavior of Amorphous Solid Dispersions. J. Pharm. Sci. 100(8):3316-3331. http://dx.doi.org/10.1002/jps.22579

94. Wanapun, D., Kestur, U. S., Kissick, D. J., Taylor, L. S., and Simpson, G. J. (2011) Single particle nonlinear optical imaging of trace crystallinity in an organic powder. Anal. Chem. 83(12):4745-4751. http://dx.doi.org/10.1021/ac1031397

93. Zhou, Q. Harris, M. T., and Taylor L. S. (2011) Time-resolved SAXS/WAXS study of the phase behavior and microstructural evolution of drug/PEG solid dispersions. Mol. Pharm. 8(3):932-939. http://dx.doi.org/10.1021/mp200041j

92. Baird, J. A. and Taylor, L. S. (2011) Evaluation and Modeling of the Eutectic Composition of Various Drug-Polyethylene Glycol Solid Dispersions. Pharmaceutical Development and Technology. 16(3):201-211 http://dx.doi.org/10.3109/10837450903584936

91. Van Eerdenbrugh, B., Alonzo, D. E. and Taylor L. S. (2011). Influence of particle size on the ultraviolet spectrum of particulate-containing solutions – implications for in-situ concentration monitoring using UV/Vis fiber-optic probes. Pharm. Res. 28(7):1643-1652. http://dx.doi.org/10.1007/s11095-011-0399-4

90. Sung,P-F., Hsieh Y-L., Angonese, K. Dunn, D., King, K., Machbitz, R., Christianson, A. Taylor, L. S., Harris, M. T., (2011) Complex Dielectric Properties of Microcrystalline Cellulose (MCC), Anhydrous Lactose and α-Lactose Monohydrate Powders Using a Microwave-Based Open Reflection Resonator Sensor. J. Pharm. Sci. 100(7):2920-2934 http://dx.doi.org/10.1002/jps.22516

89. Li, N., Taylor, L.S., and Mauer, L.J. (2011) Degradation kinetics of catechins in green tea powder: Effects of temperature and relative humidity. J. Agric. Food Chem. 59(11):6082-6090. http://dx.doi.org/10.1021/jf200203n

88. Van Eerdenbrugh, B., and Taylor L. S. (2011). Application of Mid-IR Spectroscopy for the Characterization of Pharmaceutical Systems. International Journal of Pharmaceutics. 417:3-16. http://dx.doi.org/10.1016/j.ijpharm.2010.12.011

87. Hiatt, A. N., Taylor, L. S. and Mauer, L. J. (2011). Effects of co-formulation of amorphous maltodextrin and deliquescent sodium ascorbate on moisture sorption and stability. International Journal of Food Properties. 14(4):726-740. http://dx.doi.org/10.1080/10942910903374114 .

86. Guerrieri, P., Zemlyanov, D., and Taylor, L.S. (2011) A study of water adsorption on organic crystal surfaces using a modified X-ray photoelectron spectroscopy instrument. Anal. Chem. 83(3):1144-1147. http://dx.doi.org/10.1021/ac102550e

85. Van Eerdenbrugh, B., Fanwick, P. E. and Taylor L. S. (2010).2-Butoxy-N-[2-(diethylamino)ethyl]-quinoline-4-carboxamide (dibucaine). Acta Crystallographica E. E66 o3189. http://dx.doi.org/10.1107/S1600536810045460

84. Kwok, K., Mauer, L. J. and Taylor, L.S. (2010) Kinetics of moisture-induced hydrolysis in powder blends stored at and below the deliquescence relative humidity: investigation of sucrose-citric acid mixtures. Journal of Agricultural and Food Chemistry. 58(22):11716-11724. http://dx.doi.org/10.1021/jf101941e

83. Van Eerdenbrugh, B., Fanwick, P. E. and Taylor L. S. (2010). 1-[(Biphenyl-4-yl)(phenyl)methyl]-1H-imidazole (bifonazole). Acta Crystallographica Section E. E66 o2649. http://dx.doi.org/10.1107/S1600536810037876

82. Van Eerdenbrugh, B., Fanwick, P. E. and Taylor L. S. (2010). 2-(Biphenyl-4-yl)acetic acid (felbinac). Acta Crystallographica E. E66 o2609. http://dx.doi.org/10.1107/S1600536810035828

81. Rumondor, A.C.F. and Taylor, L.S. (2010) Application of Partial Least Squares (PLS) Modeling in Quantifying Drug Crystallinity in Amorphous Solid Dispersions. International Journal of Pharmaceutics.398(1-2):155-160. http://dx.doi.org/10.1016/j.ijpharm.2010.07.049

80. Guerrieri, P., Rumondor, A.C.F., Li, T, and Taylor, L.S. (2010). Analysis of relationships between solid-state properties, counterion and developability of pharmaceutical salts. AAPS PharmSciTech. 11(3) 1212-1222. http://dx.doi.org/10.1208/s12249-010-9499-4

79. Zhou, Q., Taylor L. S. and Harris, M. T. (2010) Evaluation of the Microstructure of Semicrystalline Solid Dispersions. Molecular Pharmaceutics. 7(4):1291-1337. http://dx.doi.org/10.1021/mp1000907

78. Van Eerdenbrugh, B., and Taylor L. S. (2010). Small Scale Screening to determine the Ability of Different Polymers to Inhibit Drug Crystallization upon Rapid Solvent Evaporation. Molecular Pharmaceutics. 7(4):1328-1337. http://dx.doi.org/10.1021/mp1001153

77. Kestur, U. S., Lee, H., Santiago, D., Rinaldi, C., Won, Y-Y. and Taylor, L. S. (2010) Effects of the Molecular Weight and Concentration of Polymer Additives, and Temperature on the Melt Crystallization Kinetics of a Small Drug Molecule. Crystal Growth and Design. 10(8):3585-3596. http://dx.doi.org/10.1021/cg1004853

76. Kwok, K., Mauer, L. J. and Taylor, L.S. (2010) Phase Behavior and Moisture Sorption Behavior of Deliquescent Powders. Chemical Engineering Science. 65:5639-5650 http://dx.doi.org/10.1016/j.ces.2010.06.012.

75. Guerrieri, P., Zemlyanov, D., and Taylor, L.S. (2010) Dissociation of Water on the Surface of Organic Salts studied by X-ray Photoelectron Spectroscopy. Langmuir. 26(14): 11998-12002 http://dx.doi.org/10.1021/la101501p

74. Wanapun, D., Kestur, U. S., Kissick, D. J.,Simpson, G. J., and Taylor, L. S. (2010) Selective Detection and Quantitation of Organic Molecule Crystallization by Second Harmonic Generation Microscopy. Analytical Chemistry. 82(13): 5425-5432. http://dx.doi.org/10.1021/ac100564f

73. Van Eerdenbrugh, B., Baird, J. A. and Taylor, L. S. (2010). Crystallization tendency of active pharmaceutical ingredients following rapid solvent evaporation – classification and comparison with crystallization tendency from undercooled melts. Journal of Pharmaceutical Sciences. 99(9):3826-3838. http://dx.doi.org/10.1002/jps.22214

72. Baird, J. A., Van Eerdenbrugh, B and Taylor, L. S. (2010). A Classification System to Assess the Crystallization Tendency of Organic Molecules from Undercooled Melts. Journal of Pharmaceutical Sciences. 99(9):3787-3806. http://dx.doi.org/10.1002/jps.22197

71. Kestur, U.S. and Taylor, L.S. (2010). Role of Polymer Chemistry in Influencing Crystal Growth Rates from Amorphous Felodipine. CrystEngComm. 12:2390-2397. http://dx.doi.org/10.1039/c001905d

70. Hiatt, A. N., Ferruzzi, M. G., Taylor, L. S. and Mauer, L. J. (2011) Deliquescence behavior and chemical stability of vitamin C forms (ascorbic acid, sodium ascorbate, and calcium ascorbate) and blends. International Journal of Food Properties. 14(6):1330-1348 http://dx.doi.org/10.1080/10942911003650338

69. Hiatt, A. N., Taylor, L. S. and Mauer, L. J. (2010) Influence of simultaneous variations in temperature and relative humidity on chemical degradation of two vitamin C forms and implications for shelf-life models. Journal of Agricultural and Food Chemistry 58(6):3532-3540. http://dx.doi.org/10.1021/jf903342f

68. Rumondor, A.C.F. and Taylor, L.S. (2010) Effect of Polymer Hygroscopicity on the Phase Behavior of Amorphous Solid Dispersions in the Presence of Moisture. Molecular Pharmaceutics. 7(2):477-490. http://dx.doi.org/10.1021/mp9002283

67. Alonzo, D.E., Zhang, G.G.Z., Zhou, D., Gao, Y., and Taylor, L.S. Understanding the Behaviour of Amorphous Pharmaceutical Systems During Dissolution. Pharmaceutical Research 27(4):608-618. http://dx.doi.org/10.1007/s11095-009-0021-1

66. Rumondor, A.C.F., Konno, H., Marsac, P.J., and Taylor, L. S. (2010) Analysis of the Moisture Sorption Behavior of Amorphous Drug-Polymer Blends. Journal of Applied Polymer Science 117(2):1055-1063. http://dx.doi.org/10.1002/app.31803 .

65. Mauer L. J. and Taylor, L. S. (2010). Water-Solids Interactions: Deliquescence. Annual Review of Food Science and Technology. 1:41-63. http://dx.doi.org/10.1146/annurev.food.080708.100915

64. Guerrieri, P., Jarring, K., and Taylor, L.S. (2010) Impact of Counterion on the Chemical Stability of Crystalline Salts of Procaine. J. Pharm. Sci. 99(9):3719-3730. http://dx.doi.org/10.1002/jps.22009

63. Rumondor, A.C.F., Jackson, M.J. and Taylor, L.S. (2010) Effects of Moisture on the Growth Rate of Felodipine Crystals in the Presence and Absence of Polymers. Crystal Growth and Design. 10(2):747-753. http://dx.doi.org/10.1021/cg901157w

62. Mauer L. J. and Taylor, L. S. (2010). Deliquescence of Pharmaceutical Systems. Pharmaceutical Development and Technology. 15(6):582-594. http://dx.doi.org/10.3109/10837450903397594

61. Marsac, P.J., Rumondor, A.C.F., Nivens, D. E., Kestur, U. S.; Stanciu, L. and Taylor, L. S. (2010) Effect of Temperature and Moisture on the Miscibility of Amorphous Dispersions of Felodipine and Poly(vinyl pyrrolidone). Journal of Pharmaceutical Sciences. 99(1):169-185 http://dx.doi.org/10.1002/jps.21809.

60. Baird, J., Olayo-Valles, R., Rinaldi, C. and Taylor, L. S. (2010) Effect of Molecular Weight, Temperature, and Additives on the Moisture Sorption Properties of Polyethylene Glycol.Journal of Pharmaceutical Sciences. 99(1):154-168 http://dx.doi.org/10.1002/jps.21808.

59. Rumondor, A.C.F., Stanford, L. A. and Taylor, L.S. (2009) Effect of Polymer Type and Storage Relative Humidity on the Kinetics of Felodipine Crystallization from Amorphous Solid Dispersions. Pharm. Res. 26 (12):2599-2606. http://dx.doi.org/10.1007/s11095-009-9974-3

58. Rumondor, A.C.F., Ivanisevic, I., Bates, S., Alonzo, D. E. and Taylor, L. S. (2009) Evaluation of Drug-Polymer Miscibility in Amorphous Solid Dispersion Systems. Pharm. Res. 26 (11):2523-2534. http://dx.doi.org/10.1007/s11095-009-9970-7

57. Rumondor, A.C.F., Marsac, P.J., Stanford, L. A., and Taylor, L. S. (2009) Phase Behavior of Poly(vinylpyrrolidone) Containing Amorphous Solid Dispersions in the Presence of Moisture. Molecular Pharmaceutics. 6 (5):1492-1505. http://dx.doi.org/10.1021/mp900050c

56. Guerrieri, P., and Taylor, L.S. (2009) Role of salt and excipient properties on disproportionation in the solid-state. Pharmaceutical Research 26(8):2015-2026. http://dx.doi.org/10.1007/s11095-009-9918-y

55. Ortiz, J., Kestur U., Taylor, L.S. and Mauer, L.J. (2009) Interaction of environmental moisture with powdered green tea formulations: Relationship between catechin stability and moisture-induced phase transformations. Journal of Agricultural and Food Chemistry. 57(11):4691-4697.http://dx.doi.org/10.1021/jf8038583

54. Gift, A.D., Luner, P.E., Luedeman, L., and Taylor, L.S. (2009). Manipulating hydrate formation during high shear wet granulation using polymeric excipients. Journal of Pharmaceutical Sciences. 98(12):4670-4683. http://dx.doi.org/10.1002/jps.21763

53. Wikström, H., Kakidas, C. and Taylor, L.S. (2009). Determination of hydrate transition temperature using transformation kinetics obtained using Raman spectroscopy. Journal of Pharmaceutical and Biomedical Analysis. 49:247-252. http://dx.doi.org/10.1016/j.jpba.2008.11.008

52. Marsac, P.J., Li, T., and Taylor, L. S. (2009) Estimation of Drug-Polymer Miscibility and Solubility in Amorphous Solid Dispersions using Experimentally Determined Interaction Parameters. Pharmaceutical Research. 26(1):139-151. http://dx.doi.org/10.1007/s11095-008-9721-1

51. Konno, H., Handa, T., Alonzo, D. E. and Taylor, L. S. (2008). Effect of Polymer Type on the Dissolution Profile of Amorphous Solid Dispersions Containing Felodipine. European Journal of Pharmaceutics and Biopharmaceutics. 70:493-499. http://dx.doi.org/10.1016/j.ejpb.2008.05.023

50. Hiatt, A.N. Ferruzzi, M., Taylor, L.S., and Mauer, L. J. (2008) Impact of deliquescence on the chemical stability of vitamins B1, B6, and C in powder blends. Journal of Agricultural and Food Chemistry. 56 (15): 6471–6479. http://dx.doi.org/10.1021/jf800709f

49. Towler C. S., Li, T. Wikström, H, Remmick, D., Sanchez-Felix M. V. and Taylor, L. S. (2008) An investigation into the influence of counter-ion on the properties of some amorphous organic salts. Molecular Pharmaceutics. 5 (6): 946-955. http://dx.doi.org/10.1021/mp8000342

48. Wikström, H.; Rantanen, J.; Gift, A. D. and Taylor, L. S. (2008) Towards an understanding of the factors influencing anhydrate-to-hydrate transformation kinetics in aqueous environments. Crystal Growth and Design. 8 (8): 2684–2693. http://dx.doi.org/10.1021/cg070629e

47. Ortiz, J., Ferruzzi, M., Taylor, L.S. and Mauer, L.J. (2008) Interaction of Environmental Moisture with Powdered Green Tea Formulations: Effect on Catechin Chemical Stability. Journal of Agricultural and Food Chemistry 56:4068-4077. http://dx.doi.org/10.1021/jf800246s

46. Gift, A.D., Luner, P.E., Luedeman, L., and Taylor, L.S. (2008) Influence of Polymeric Excipients on Crystal Hydrate Formation Kinetics in Aqueous Slurries. Journal of Pharmaceutical Sciences 97:5198-5211. http://dx.doi.org/10.1002/jps.21379

45. Marsac, P.J., Romary, D.P., Shamblin, S.L., Baird, J.A., and Taylor, L.S. (2008) Spontaneous Crystallinity Loss of Drugs in the Disordered Regions of Poly(ethylene oxide) in the Presence of Water. Journal of Pharmaceutical Sciences. 97: 3182-3194. http://dx.doi.org/10.1002/jps.21237

44. Guerrieri, P., Smith, D.T., and Taylor, L.S. (2008) Phase Behavior of Ranitidine HCl in the Presence of Atmospheric Moisture and Degradants – Influence on Chemical Reactivity. Langmuir 24:3850-3856. http://dx.doi.org/10.1021/la703031c

43. Wikström, H., Carroll, W.J., and Taylor, L.S. (2008) Manipulating theophylline hydrate formation during high shear wet granulation through improved understanding of the role of pharmaceutical excipients. Pharmaceutical Research.25(4):923-978. http://dx.doi.org/10.1007/s11095-007-9450-x

42. Konno, H., and Taylor, L.S. (2008) Ability of Different Polymers to Inhibit the Crystallization of Amorphous Felodipine in the Presence of Moisture. Pharmaceutical Research 25(4): 969-978. http://dx.doi.org/10.1007/s11095-007-9331-3

41. Marsac, P.J., Konno, H., Rumondor, A.C.F., and Taylor, L.S. (2008) Recrystallization of Nifedipine and Felodipine from Amorphous Molecular Level Solid Dispersions Containing Poly(vinylpyrrolidone) and Sorbed Water. Pharmaceutical Research 25 (3):647-656. http://dx.doi.org/10.1007/s11095-007-9420-3

40. Hu, Y., Wikström, H., Byrn, S.R., and Taylor, L.S. (2007) Estimation of the Transition Temperature for an Enantiotropic Polymorphic System from the Transformation Kinetics Monitored using Raman Spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 45:546–551. http://dx.doi.org/10.1016/j.jpba.2007.07.028

39. Romero-Torres, S., Wikström, H., Grant, E.R., and Taylor L.S. (2007) Monitoring of Mannitol Phase Behavior during Freeze-Drying Using Non-Invasive Raman Spectroscopy. PDA Journal of Pharmaceutical Science and Technology 61(2):131-145.

38. Towler, C.S., and Taylor, L.S. (2007) Spectroscopic Characterization of Inter-Molecular Interactions in Solution and Their Influence on Crystallization Outcome. Crystal Growth and Design 7(4):633-638. http://dx.doi.org/10.1021/cg0602358

37. Gift, A.D., and Taylor, L.S. (2007) Hyphenation of Raman Spectroscopy with Gravimetric Analysis to Interrogate Water-Solid Interactions in Pharmaceutical Systems. Journal of Pharmaceutical and Biomedical Analysis 43:14-23. http://dx.doi.org/10.1016/j.jpba.2006.06.025

36. Guerrieri P., Salameh A.K., and Taylor, L.S. (2007) Effect of Small Levels of Impurities on the Moisture Sorption Behavior of Ranitidine HCl. Pharmaceutical Research 24(1):147-156. http://dx.doi.org/10.1007/s11095-006-9134-y

35. Salameh, A.K., and Taylor, L.S. (2006) Deliquescence Induced Caking in Binary Powder Blends. Pharmaceutical Development and Technology 11:453-464. http://dx.doi.org/10.1080/10837450600939057

34. Konno, H., and Taylor, L.S. (2006) Influence of Different Polymers on the Crystallization Tendency of Molecularly Dispersed Amorphous Felodipine. Journal of Pharmaceutical Sciences 95(12):2692-2705. http://dx.doi.org/10.1002/jps.20697

33. Marsac, P.J., Shamblin, S.L., and Taylor, L.S. (2006) Theoretical and Practical Approaches for Prediction of Drug-Polymer Miscibility and Solubility. Pharmaceutical Research 23(10):2417-2425. http://dx.doi.org/10.1007/s11095-006-9063-9

32. Marsac, P.J., Konno, H., and Taylor, L.S. (2006) A Comparison of the Physical Stability of Amorphous Felodipine and Nifedipine Systems. Pharmaceutical Research 23(10):2306-2316. http://dx.doi.org/10.1007/s11095-006-9047-9

31. Hu, Y., Wikström, H., Byrn S.R., and Taylor, L.S. (2006) Analysis of the Effect of Particle Size on Polymorphic Quantitation by Raman Spectroscopy. Applied Spectroscopy 60(9):977-984. http://dx.doi.org/10.1366/000370206778397272

30. Wikström, H., Romero-Torres, S., Wongweragiat, S., Stuart Williams, J.A., Grant, E.R., and Taylor, L.S. (2006) On-Line Content Uniformity Determination of Tablets Using Low-Resolution Raman Spectroscopy. Applied Spectroscopy 60(6):672-681. http://dx.doi.org/10.1366/000370206777670684

29. Salameh, A.K., and Taylor, L.S. (2006) The Role of Deliquescence Lowering in Enhancing Chemical Reactivity in Physical Mixtures. Journal of Physical Chemistry B 110(20):10190-10196. http://dx.doi.org/10.1021/jp0612376

28. Salameh, A.K., Mauer L.J., and Taylor, L.S. (2006) Deliquescence Lowering in Food Ingredient Mixtures. Journal of Food Science 71(1):E10-E16

27. Salameh, A.K., and Taylor, L.S. (2006) Physical Stability of Crystal Hydrates and Their Anhydrates in the Presence of Excipients. Journal of Pharmaceutical Sciences 95(2):446-461. http://dx.doi.org/10.1002/jps.20532

26. Rantanen, J., Wikström, H., Rhea, F.E., and Taylor, L.S. (2005) Improved Understanding of Factors Contributing to Quantification of Anhydrate/Hydrate Powder Mixtures. Applied Spectroscopy 59(7):942-951. http://dx.doi.org/10.1366/0003702054411670

25. Wikström, H., Lewis, I.R., and Taylor, L.S. (2005) Comparison of Sampling Techniques for In-Line Monitoring Using Raman Spectroscopy. Applied Spectroscopy 59(7):934-941. http://dx.doi.org/10.1002/jps.20241

24. Salameh, A.K., and Taylor, L.S. (2005) Deliquescence in Binary Mixtures. Pharmaceutical Research 22(2):318-324. http://dx.doi.org/10.1007/s11095-005-1563-5

23. Rantanen, J., Wikström, H., Turner, R., and Taylor, L.S. (2005) Use of In-Line Near- Infrared Spectroscopy in Combination with Chemometrics for Improved Understanding of Pharmaceutical Processes. Analytical Chemistry 77(2):556-563. http://dx.doi.org/10.1021/ac048842u

22. Hu, Y., Liang, J., Myerson, A., and Taylor, L.S. (2005) Crystallization Monitoring by Raman Spectroscopy: Simultaneous Measurement of Desupersaturation Profile and Polymorphic Form in Flufenamic Acid Systems. Industrial and Engineering Chemistry Research 44(5):1233-1240. http://dx.doi.org/10.1021/ie049745u

21. Wikström, H., Marsac, P.J., and Taylor, L.S. (2005) In-Line Monitoring of Hydrate Formation During Wet Granulation Using Raman Spectroscopy. Journal of Pharmaceutical Sciences 94(1):209-219. http://dx.doi.org/10.1002/jps.20241

20. Ringqvist, A., Taylor, L.S.,Ekelund, K., Ragnarsson, G., Engströme, S., and Axelsson, A. (2003) Atomic Force Microscopy Analysis and Confocal Raman Microimaging of Coated Pellets. International Journal of Pharmaceutics 267(1-2):35 47. http://dx.doi.org/10.1016/j.ijpharm.2003.07.004

19. Santesson, S., Johansson, J., Taylor, L.S., Levander, I., Fox, S., Sepaniak, M., and Nilsson, S. (2003) Airborne Chemistry Coupled with Raman Spectroscopy. Analytical Chemistry 75(9):2177-2180. http://dx.doi.org/10.1021/ac026302w

18. Johansson, J., Pettersson, S. and Taylor, L.S. (2002) Infrared Imaging of Laser-Induced Heating During Raman Spectroscopy of Pharmaceuticals. Journal of Pharmaceutical and Biomedical Analysis 30:1223-1231. http://dx.doi.org/10.1016/S0731-7085(02)00461-2

17. Ahlqvist, M.U.A., and Taylor, L.S. (2002) Water Dynamics in Channel Hydrates Investigated Using H/D Exchange. International Journal of Pharmaceutics 241(2):253-261. http://dx.doi.org/10.1016/S0378-5173(02)00242-9

16. Tong, P., Taylor, L.S., and Zografi, G. (2002) Influence of Alkali Metal Counterions on the Glass Transition Temperature of Amorphous Indomethacin Salts. Pharmaceutical Research 19(5):649-654. http://dx.doi.org/10.1023/A:1015310213887

15. Tang, X.C., Pikal, M.J., and Taylor, L.S. (2002) The Effect of Temperature on Hydrogen Bonding in Crystalline and Amorphous Phases in Dihydropyridine Calcium Channel Blockers. Pharmaceutical Research 19(4):484-490. http://dx.doi.org/10.1023/A:1015199713635

14. Tang, X.C., Pikal, M.J., and Taylor, L.S. (2002) A Spectroscopic Investigation of Hydrogen Bond Patterns in Crystalline and Amorphous Phases in Dihydropyridine Calcium Channel Blockers. Pharmaceutical Research 19(4):477-483. http://dx.doi.org/10.1023/A:1015147729564

13. Ahlqvist, M.U.A., and Taylor, L.S. (2002) Water Diffusion in Hydrated Crystalline and Amorphous Sugars Monitored Using H/D Exchange. Journal of Pharmaceutical Sciences 9(3):690-698. http://dx.doi.org/10.1002/jps.10068

12. Broman, E.; Khoo, C., and Taylor, L.S. (2001) A Comparison of Alternative Polymer Excipients and Processing Methods For Making Solid Dispersions of a Poorly Water Soluble Drug. International Journal of Pharmaceutics 222(1):139-151. http://dx.doi.org/10.1016/S0378-5173(01)00709-8

11. Taylor, L.S., and Langkilde F.W., and Zografi, G. (2001) Fourier Transform Raman Spectroscopic Study of the Interaction of Water Vapor with Amorphous Polymers. Journal of Pharmaceutical Sciences 90(7):888-901. http://dx.doi.org/10.1002/jps.1041

10. Taylor, L.S., and Langkilde F.W. (2000) Evaluation of Solid State Forms Present in Tablets by Raman Spectroscopy. Journal of Pharmaceutical Sciences 89(10):1342-1353. http://dx.doi.org/10.1002/1520-6017(200010)89:10<1342::AID-JPS12>3.0.CO;2-X

9. Taylor, L.S., and Zografi, G. (1998) Sugar-Polymer Hydrogen Bond Interactions in Lyophilised Amorphous Mixtures. Journal of Pharmaceutical Sciences 87(12):1615-1621. http://dx.doi.org/10.1021/js9800174

8. Shamblin, S.L., Taylor, L.S., and Zografi, G., and (1998) Mixing Behavior of Colyophilized Binary Systems. Journal of Pharmaceutical Sciences 87(6):694-701. http://dx.doi.org/10.1021/JS9704801

7. Taylor, L.S., and Zografi, G. (1998) The Quantitative Analysis of Crystallinity Using FT-Raman Spectroscopy. Pharmaceutical Research 15(5):755-761. http://dx.doi.org/10.1023/A:1011979221685

6. Taylor, L.S., and York, P. (1998) Effect of Particle Size and Temperature on the Dehydration Kinetics of Trehalose Dihydrate. International Journal of Pharmaceutics 167(1-2):215-221. http://dx.doi.org/10.1016/S0378-5173(98)00065-9

5. Taylor, L.S.; Williams, A.C.; and York, P. (1998) Particle Size Dependent Molecular Rearrangements During the Dehydration of Trehalose Dihydrate-In Situ FT-Raman Spectroscopy. Pharmaceutical Research 15(8):1207-1214. http://dx.doi.org/10.1023/A:011935723444

4. Taylor, L.S., and York, P. (1998) Characterization of the Phase Transitions of Trehalose Dihydrate on Heating and Subsequent Dehydration. Journal of Pharmaceutical Sciences 87(3):347-355. http://dx.doi.org/10.1021/js970239m

3. Taylor, L.S., and Zografi, G. (1997) Spectroscopic Characterization of Interactions between PVP and Indomethacin in Amorphous Molecular Dispersions. Pharmaceutical Research 14(12):1691-1698. http://dx.doi.org/10.1023/A:1012167410376

2. Taylor, L.S.; Williams, A.C.; and Mehta, V., and York, P. (1997) Characterization of Frozen Glucose Solutions. Pharmaceutical Development and Technology 2(4):395-402.

1. Taylor, L.S.; Williams, A.C.; Edwards, H.G.M.; Mehta, V.; Jackson, G.S.; Badcoe, I.G.; and Clarke, A., and York, P. (1995) Sucrose Reduces the Efficiency of Protein Denaturation by a Chaotropic Agent. Biochimica et Biophysica Acta 1253(1):39-46. http://dx.doi.org/10.1016/0167-4838(95)00142-H