Publications

Reviewed Journal Publications

1. Win MN and Smolke CD. A modular and extensible RNA-based gene-regulatory platform for engineering cellular function. Proc Natl Acad Sci U S A 2007 Sep 4; 104(36) 14283-8. doi:10.1073/pnas.0703961104 pmid:17709748. PubMed HubMed [win2]
2. Win MN, Klein JS, and Smolke CD. Codeine-binding RNA aptamers and rapid determination of their binding constants using a direct coupling surface plasmon resonance assay. Nucleic Acids Res 2006; 34(19) 5670-82. doi:10.1093/nar/gkl718 pmid:17038331. PubMed HubMed [win]
3. Hawkins KM and Smolke CD. The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae. J Biol Chem 2006 May 12; 281(19) 13485-92. doi:10.1074/jbc.M512317200 pmid:16524886. PubMed HubMed [hawkins]
4. Pfleger BF, Pitera DJ, Smolke CD, and Keasling JD. Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes. Nat Biotechnol 2006 Aug; 24(8) 1027-32. doi:10.1038/nbt1226 pmid:16845378. PubMed HubMed [pfleger]
5. Bayer TS and Smolke CD. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nat Biotechnol 2005 Mar; 23(3) 337-43. doi:10.1038/nbt1069 pmid:15723047. PubMed HubMed [bayer]
6. Isaacs FJ and Collins JJ. Plug-and-play with RNA. Nat Biotechnol 2005 Mar; 23(3) 306-7. doi:10.1038/nbt0305-306 pmid:15765083. PubMed HubMed [isaacs]
7. Smolke CD and Keasling JD. Effect of gene location, mRNA secondary structures, and RNase sites on expression of two genes in an engineered operon. Biotechnol Bioeng 2002 Dec 30; 80(7) 762-76. doi:10.1002/bit.10434 pmid:12402322. PubMed HubMed [smolke1]
8. Smolke CD and Keasling JD. Effect of copy number and mRNA processing and stabilization on transcript and protein levels from an engineered dual-gene operon. Biotechnol Bioeng 2002 May 20; 78(4) 412-24. pmid:11948448. PubMed HubMed [smolke2]
9. Smolke CD, Khlebnikov A, and Keasling JD. Effects of transcription induction homogeneity and transcript stability on expression of two genes in a constructed operon. Appl Microbiol Biotechnol 2001 Dec; 57(5-6) 689-96. pmid:11778879. PubMed HubMed [smolke3]
10. Smolke CD, Martin VJ, and Keasling JD. Controlling the metabolic flux through the carotenoid pathway using directed mRNA processing and stabilization. Metab Eng 2001 Oct; 3(4) 313-21. doi:10.1006/mben.2001.0194 pmid:11676567. PubMed HubMed [smolke4]
11. Smolke CD, Carrier TA, and Keasling JD. Coordinated, differential expression of two genes through directed mRNA cleavage and stabilization by secondary structures. Appl Environ Microbiol 2000 Dec; 66(12) 5399-405. pmid:11097920. PubMed HubMed [smolke5]

Non-Peer-Reviewed Publications

1. Bayer, T.S., Smolke, C.D. (2006) Design of nucleic acid switches. Nature Protocols. In preparation.
2. Baker, D., Church, G., Collins, J., Endy, D., Jacobson, J., Keasling, J., Modrich, P., Smolke, C., Weiss, R. (2006) Engineering Life: Building a Fab for Biology. Scientific American June issue.
3. Smolke, C. 2005. Molecular switches for cellular sensors. Engineering and Applied Science 4, 28-37
4. Martin, V.J.J., Smolke, C.D., Keasling, J.D. (2002) Redesigning cells for the production of complex organic molecules. ASM News 68, 336-343.

Books and Book Chapters

1. Smolke, C.D., editor (2006) Metabolic Engineering Protocols: Synthesis and Design Strategies. In: Walker J, series ed., Methods in Molecular Biology. Totawa: Humana Press. In preparation.
2. Smolke, C.D., editor (2006) Metabolic Engineering Protocols: Analysis and Characterization. In: Walker J, series ed., Methods in Molecular Biology. Totawa: Humana Press. In preparation.
3. Smolke, C.D., editor (2006) Handbook for Metabolic Pathway Engineering. San Diego: CRC Press. In preparation.
4. Smolke, C.D., Martin, V.J.J., Keasling, J.D. (2004) Tools for metabolic engineering in Escherichia coli. In: Baneyx, F., editor. Expression Technologies. U.K.: Horizon Scientific Press.