Piperazine

From OpenWetWare

• A piperidine-like compound with 2 N atoms at opposed (symmetrical) positions and a N-derived heterocyclic building block for chiral amino protected (peptide|oligo) synthesis, hence "solid phase peptide synthesis"...
• In Fmoc SPPS, an orthogonal protection reagent for (cis/trans) microwave-triggered peptide synthesis (MWPS).

See also

• Pyridine, and Piperidine
• Enamine
• Microwave-triggered peptide synthesis
• Fmoc (9-fluorenylmethyloxycarbonyl) solid phase peptide synthesis
• Mefloquine and Tetrahydroisoquinoline
• DMF

References

1. Palasek SA, Cox ZJ, and Collins JM. . pmid:17121420. PubMed HubMed [Stacey-A-Palasek-Zachary-J-Cox-Jonathan-M-Collins-J-Pept-Sci-2007]