Welcome to the Mukhopadhyay Group page!!
We are an interdisciplinary team at Berkeley Lab studying both engineered and environmental microbes. We are the Host Engineering group at JBEI, and we adopt targeted and systems biology approaches to elucidate causes of inhibition during fuel and chemicals production in microbial systems such as Escherichia coli and Saccharomyces cerevisiae. We focus on engineering robust hosts for metabolite production, and we develop strategies that are universally useful, for microbial host engineering. We also engineer microbes towards catabolism of environmental pollutants, where we address bioremediation of hydrocarbons, organophosphate and phosphonate compounds. We are part of the ENIGMA project where we take comprehensive systems biology approaches to examine bacterial signaling in ubiquitous and environmentally important, sulfate and metal reducing bacteria. We also study rainfall events and signaling in the fabulous cyanobacteria that dominate the desert soil crusts on our planet.
Jan 20th 2015
Flo's paper is out in Biotechnology and Bioengineering A heroic effort in generating an improved pump for a volatile organic compound. We will look to the metabolic engineering community for a hexene production strain to implement this discovery.
The Total efflux pump team: Angelique, Melissa, Florence, Aindrila and Camille (..only missing Kat and Eric)
Nov 4th 2014
We published our study on improving Isopentenol tolerance and production in the mBio journal. mBio featured it in their blog. We have gotten many more mentions (RDmag, Science Daily, Green car congress...). Congratulations to Heather, Jee Loon and the rest of the team!!
Jensen, Foo et al 2014 gets a nice write up
by Lynn Yarris and was featured on the front page of our DOE webpage!
Feb 26th 2014
KQED QUEST Career spotlight video
June 6th 2013
And we get a wonderful article in TABL by Lynn Yarris.
Lara's Microcoleus Desert soil crust paper in online in the ISME Journal
May 13th 2013
We get a chance to talk about our research at the Berkeley Rep at the Science at the theater organised by Friends of the Berkeley Lab!
March 19th 2013
We get a mention in the Department Of Energy feature on STEM profiles.
Oct 1st 2012
The whole group at the Can't Fail cafe. We have new members in the group - Amanda Reider Appel and Nhat Than Vuong!
Left to Right: Kavya, Melissa, Nhat-Tan, Lara, Marijke, Camille, Florence, Jee-Loon, Aindrila, Eric, Heather, Zain and Amanda
Feb 14th 2012
Science Today, a UC Berkeley Radio channel, features comments on our study of the D. vulgaris two component system regulator network.
Nov 9th 2011
Lara and Eric's Response Regulator Map paper gets written about in Berkeley Lab's TABL site.
Oct 15th 2011
Lara and Eric's D. vulgaris Response Regulator map paper is out in Genome Biology.
Sept 27th 2011
Mario (in the blue lab coat!!) features in the Berkeley Lab news letter TABL for his important contribution in developing Bisabolene production in yeast. Here is a link to Pamela and TaekSoon's Nature Communications paper
(Photo by Roy Kaltschmidt, Berkeley Lab)
August 22nd 2011
Zain, Heather and Aindrila feature on the cover of the Biorefining magazine. Here is the article.
July 1st 2011
Our efflux pump paper gets a mention in the Microbe magazine. Other mentions of our study are in eureka alert, techblog, science daily, microbeworld, Materials Today to list a few!!!
We receive funding from: