Efflux Pumps provide a direct mechanism to alleviate product toxicity (Image prepared by Everett Kaplan
Welcome to the Mukhopadhyay Group page!!
We are an interdisciplinary team at the Berkeley Lab studying signaling, stress response and tolerance in both environmental and engineered organisms. As the host engineering group at JBEI we adopt targeted and systems biology approaches to elucidate causes of inhibition during fuel/ solvent production from lignocellulose using the microbes such as Escherichia coli and Saccharomyces cerevisiae. We hope to engineer better hosts for metabolite production and develop tools that are universally useful for microbial cellular engineering. We are part of the ENIGMA project where our research includes the study of two component signaling in the model sulfate reducing bacterium Desulfovibrio vulgaris Hildenborough. In other bioremediation projects we address degradation of organophosphate and phosphonate compounds. We also study wetting events and signaling in the fabulous cyanobacteria that dominate the desert soil crusts on our planet.
More about Aindrila
We are funded by:
Feb 26th 2014
KQED QUEST Career spotlight video
June 6th 2013
And we get a wonderful article in TABL by Lynn Yarris.
Lara's Microcoleus Desert soil crust paper in online in the ISME Journal
May 13th 2013
We get a chance to talk about our research at the Berkeley Rep at the Science at the theater organised by Friends of the Berkeley Lab!
March 19th 2013
We get a mention in the Department Of Energy feature on STEM profiles.
Oct 1st 2012
The whole group at the Can't Fail cafe. We have new members in the group - Amanda Reider Appel and Nhat Than Vuong!
Left to Right: Kavya, Melissa, Nhat-Tan, Lara, Marijke, Camille, Florence, Jee-Loon, Aindrila, Eric, Heather, Zain and Amanda
Feb 14th 2012
Science Today, a UC Berkeley Radio channel, features comments on our study of the D. vulgaris two component system regulator network.
Nov 9th 2011
Lara and Eric's Response Regulator Map paper gets written about in Berkeley Lab's TABL site.
Oct 15th 2011
Lara and Eric's D. vulgaris Response Regulator map paper is out in Genome Biology.
Sept 27th 2011
Mario (in the blue lab coat!!) features in the Berkeley Lab news letter TABL for his important contribution in developing Bisabolene production in yeast. Here is a link to Pamela and TaekSoon's Nature Communications paper
(Photo by Roy Kaltschmidt, Berkeley Lab)
August 22nd 2011
Zain, Heather and Aindrila feature on the cover of the Biorefining magazine. Here is the article.
July 1st 2011
Our efflux pump paper gets a mention in the Microbe magazine. Other mentions of our study are in eureka alert, techblog, science daily, microbeworld, Materials Today to list a few!!!