Moore Notes 8 31 15

Group Call

• Participants: Katie, Tom, Patrick. Dongying, Guillaume, Stephen

• Tara Oceans strain level analyses (Stephen)
  • Ran phylogenetic and functional (gene loss) variation
  • Geography and environmental correlations at sampling locations
  • Tom: what fraction of reads map to reference genomes?
    • Are functional diversity profiles correlated between genome mapped and shotmap?
    • Mapping location of protein families might only be possible if we have reference genomes
    • Outlier samples might have ecological novelty
  • Patrick: high variation
  • Selection and drift
  • Tom will also follow up on protein family covariation

• Humann2
  • First maps reads to reference db (bowtie), then homology search with higher sensitivity
  • Two steps for computational efficiency

• Call time will stay at 1:30pm Mondays