Major research interests
Dr. Knipp's research interests include the molecular and functional characterization of oligopeptide transporters, where he has been focusing on the characterization of the human Peptide/Histidine Transporter 1 isoform in human intestinal and blood brain barrier cell lines.
He is interested in determining the the effect of xenobiotics, particularly delineating the roles of DEHP and Bisphenol A, on placental fatty acid homeostasis and fetal development.
He has also been interested in investigating the effects of processing induced dosage form variation on clinical performance utilizing in vitro and in vivo (porcine) models. His recent work has focused on the utilization of the porcine model for testing the pharmacokinetics of novel pediatric formulations developed within his laboratory.
Research Spotlight: Pediatric Medicines - A Tough Pill to Swallow, from the December 2011 Industrial & Physical Pharmacy Newsletter, p. 5.