Imported:YPM/Ste2 Gpa1 Ste4Ste18 coop factor

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<modelParameter>Ste2_Gpa1_Ste4Ste18_coop_factor = </modelParameter>

Definition

The factor by which prior binding to Ste4:Ste18 changes Gpa1's affinity for Ste2, and conversly its also the factor by which prior binding to Ste2 changes Gpa1's affinity for Ste4:Ste18.
Kd_Gpa1Ste4Ste18_Ste2 = Kd_Gpa1_Ste12 / Ste2_Gpa1_Ste4Ste18_coop_factor
Ste2_Gpa1_Ste4Ste18_coop_factor > 1 means that prior binding of Ste4:Ste18 to Gpa1 increases Gpa1's affinity for Ste2, and prior binding of Ste2 to Gpa1 increases Gpa1's affinity to Ste4:Ste18.

Source

• N/A

Trust

• N/A

Additional Details

See Ste2/Gpa1/Ste4:Ste18 binding rate constant constraints for more details.