IGEM:MIT/2005/Future direction

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What we have done:
Make a modular tool
Input any external signal in a controlled manner
How to improve:
Modularity
ToxR needs to be "extended to outer membrane
Test with primary and secondary antibody setup
Use antigen that is not already a dimer
Test modularity by using different antigens, signal processing systems and actuators
Usability
Activity must be characterized
Could be tested in other chassis
Feedback mechanisms and other downstream stuff to demonstrate usability
System Applications:
Biosensor
environmental application -- test for contaminates
Research tools
Replace other antibody sensors (western blots), cell-cell signaling
Long term impact
extending and easing research in synthetic biology
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