BME100 s2014:T Group11 L2

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Contents

OUR TEAM

Name: Deven Govin
Name: Deven Govin
Name: Osama Wali
Name: Osama Wali
Name: Hillary Bratlien
Name: Hillary Bratlien
Name: Allan Ross
Name: Allan Ross
Name: Sharon Li
Name: Sharon Li


LAB 2 WRITE-UP

Descriptive Statistics

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Results

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Analysis

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Summary/Discussion

In this experiment, Lipopolysaccharide (LPS) was tested in humans and rats to find out if LPS causes an effect in Inflammotin levels. For the human group, four separate dosages were administered in increasing increments of 5mg starting at 0mg. The average effect of the dosages are shown with standard deviation and standard error in Chart 1. As the humans were tested in multiple dosages ranging from 0-15mg, an ANOVA test was appropriate to compare the groups because there were more than 2 groups being analyzed. The ANOVA test was run with the results from the human sample, to determine if there was significance between and within groups of data. Based on the results of the ANOVA test there was a P-Value of 1.4E-16 which is significant as it below 0.05. Then a T-test was run to determine the significance of the data between certain groups. When each group was compared to each other, the data was significant as the calculated T-test values were lower than the corrected P-Value of 0.00833. Therefore, all group relationships in the human study were significant.

For the rat group, only two dosages were tested 0mg and 10mg. The average effect of the dosages with standard deviation and standard error are shown Chart 2. A t-test was then run to determine the significance of the results because there was only two groups being tested. The test return a P-Value of 0.8674 which proves that the LPS dosage in rats did not produce statistically significant results. In conclusion, LPS is an effective drug for affecting the Inflammotin levels in humans but not in rats.

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