BME100 f2014:Group11 L2

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Contents

OUR TEAM

Name: Aliya Yano
Name: Aliya Yano
Name: Breanna Corrigan
Name: Breanna Corrigan
Name: Julian Lopez
Name: Julian Lopez
Name: Carlos Cabanes
Name: Carlos Cabanes
Name: Mohammed Almaimani
Name: Mohammed Almaimani

LAB 2 WRITE-UP

Descriptive Statistics

Experiment 1

Rat Study

LPS Dose Average Standard Deviation Standard Error
0mg 10.516 2.225551617 0.995296941
10mg 11.112 7.402885924 3.310671231


Full_Rat_Study.jpg



Experiment 2

Human Study

LPS Dose Average Standard Deviation Standard Error
0mg 3.834 1.523010177 2.611737366
5mg 8.932 1.593931547 3.374809028
10mg 61.622 30.11069386 11.41919326
15mg 657.941 7.402885924 31.65975232


Full_Human_Study.png




Results

Experiment 1
Rat Study

Rat_Study.jpg



Experiment 2
Human Study

Human_Study.jpg





Analysis

Experiment 1
For the rat study, an unpaired t-test was conducted. This was the test of choice because there were only two groups of dosage levels and the subjects were all different.
This test produced a P-value of 0.867. This is larger than 0.05 and would suggest that there is no statistical difference.
Rat study T-test



Experiment 2
For the human studies experiment, an ANOVA test was chosen because there are more than two dosage levels being compared.
The test produced a P-value of 1.4X10^-16. This is significantly smaller than 0.05, therefore there is a statistical difference between the groups.
ANOVA Graph

Human study Anova



Summary/Discussion

The date gathered from the human study suggests that the LPS treatments did indeed increase Inflammotin levels in the elderly patients. Of course, the higher the dosage the greater the increase. This was proven correct by the ANOVA test, which found a P-value of 1.40X10^-16. This value is much lower than 0.05 and proves there to be a significant statistical difference between the groups. However, this was not the same in the test conducted on rats. The t-test for that experiment found a P-value of .867 which is greater than 0.05 and suggests that there was no statistically significant difference between the groups. Of course, we cannot always assume that treatments will affect rats and humans the same way. What works on a human may not work on a rat and vice versa. The LPS treatments increased Inflammotin levels in humans but it did not have any clear results in rats.

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