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<h3><font style="color:#31B404;">Research</font></h3>


<h3><font style="color:#F8B603;">Research</font></h3>
The Pecinka lab is hosted by the [http://www.mpipz.mpg.de/10574/koornneef-dpt Department of Plant Breeding and Genetics] at the [http://www.mpipz.mpg.de/2169/en Max Planck Institute for Plant Breeding Research] in Cologne, Germany.


The goal of Pecinka lab is to understand molecular basis of mechanisms shaping plant genomes. We focus in particular on DNA repair and inactivation of repetitive DNA that both have potential to cause large genomic chages. To this end we use model species Arabidopsis thaliana and several other Brassicaceae and analyze them using forward and reverse genetics, molecular, biochemical, cytogenetic and bioinformatic methods.


Pecinka lab is hosted by the Department of Plant Breeding and Genetics at the Max Planck Institute for Plant Breeding Research in Cologne, Germany.
Our goal is to understand molecular and evolutionary mechanisms shaping plant genomes and epigenomes. We analyze how DNA sequence and chromatin changes are generated by endo- and exogenous factors and how these forces are balanced by the genome repair and epigenetic mechanisms. To this end we use mainly the model plant ''Arabidopsis thaliana'' and several other ''Brassicaceae'' and analyze them by forward and reverse genetics, molecular, biochemical, cytogenetic and bioinformatic methods.
[[Pecinka_lab:Research | read more...]]
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Our wiki site is developed under Openwetware, an open access effort to promote the sharing of information among researchers working in biology.
<h3><font style="color:#4169E1;">Lab Members</font></h3>
[[Pecinka_Lab:Research | read more...]]
*[[Pecinka_lab:Ales_Pecinka|Ales Pecinka]]
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<h3><font style="color:#C9D3EB;">Lab Members</font></h3>
*[[Pecinka_lab:Heinrich Bente|Heinrich Bente]]
*[[Pecinka_lab:Mariana_Diaz|Mariana Andrea Diaz Smoje]]
*[[Pecinka_lab:Andreas_Finke|Andreas Finke]]
*[[Pecinka_lab:Chun Hsin Liu|Chun Hsin Liu (Phoebe)]]
*[[Pecinka_lab:Catarine Markus|Catarine Markus]]
*[[Pecinka_lab:Kashif Nawaz|Kashif Nawaz]]
*[[Pecinka_lab:Bjoern_Pietzenuk|Björn Pietzenuk]]


*[[Pecinka_Lab:Ahmed_Abdelsamad|Ahmed Abdelsamad]]
<h3><font style="color:#4169E1;">Technitians</font></h3>
*[[Pecinka_Lab:Chun Hsin Liu|Chun Hsin Liu (Phoebe)]]
*[[Pecinka_lab:Barbara_Eilts|Barbara Eilts]]
*[[Pecinka_Lab:Ales_Pecinka|Ales Pecinka]]
*[[Pecinka_lab:Petra_Pecinkova|Petra Pecinkova]]
*[[Pecinka_Lab:Petra_Pecinkova|Petra Pecinkova]]
*[[Pecinka_Lab:Björn_Pietzenuk|Björn Pietzenuk]]
*[[Pecinka_Lab:Thomas_Piofczyk|Thomas Piofczyk]]
*[[Pecinka_Lab:Giang Vu|Giang Vu]]


<h3><font style="color:#C9D3EB;">Visiting Scholars</font></h3>
*[[Pecinka_Lab:Pawel_Mikulski|Pawel Mikulski]]


<h3><font style="color:#C9D3EB;">Alumni</font></h3>
[[Pecinka_lab:People|see complete list...]]
*[[Pecinka_Lab:Alexander Schott|Alexander Schott]]
 
*[[Pecinka_Lab:Anastasia Hoffmann|Anastasia Hoffmann]]
 
[[Pecinka_Lab:Alumni|See all former members...]]
 
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<h3><font style="color:#FF8C00;">Recent Publications</font></h3>
 
*Cao H.X., Schmutzer T, Scholz U, Pecinka A, Schubert I, Vu G.T.H. (2015): Metatranscriptome analysis reveals host-microbiome interactions in traps of carnivorous Genlisea species. Frontiers in Microbiology doi: 10.3389/fmicb.2015.00526 [http://journal.frontiersin.org/article/10.3389/fmicb.2015.00526/abstract Open access]
*Liu C-H, Finke A, Diaz M, Rozhon W, Poppenberger B, Baubec T, Pecinka A. (2015): Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis. Plant Cell doi/10.1105/tpc.114.135467 [http://www.plantcell.org/content/early/2015/05/28/tpc.114.135467.full.pdf+html Open access].
*Baranauskė S, Mickutė M, Plotnikova A, Finke A, Venclovas Č, Klimašauskas S, Vilkaitis G. (2015): Functional mapping of the plant small RNA methyltransferase: HEN1 physically interacts with HYL1 and DICER-LIKE 1 proteins. Nucleic Acids Research 43:2802-2812 [http://nar.oxfordjournals.org/content/43/5/2802.long Full text]
*Willing, Rawat et al. (2015): Genome expansion of Arabis alpina linked with retrotransposition and reduced symmetric DNA methylation. Nature Plants 1:1-7 [http://www.nature.com/articles/nplants201423 Full text]
 
 
 


<h3><font style="color:#C9D3EB;">Selected Publications</font></h3>
*[[Pecinka_lab:Publications|see complete list...]]


*Kerwin, R. E., Jimenez-Gomez, J. M., Fulop, D., Harmer, S. L., Maloof, J. N. & Kliebenstein, D. J. Network Quantitative Trait Loci Mapping of Circadian Clock Outputs Identifies Metabolic Pathway-to-Clock Linkages in Arabidopsis. Plant Cell 23, 471-485 (2011).  [http://dx.doi.org/10.1105/tpc.110.082065]
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*Nozue, K., Harmer, S. L. & Maloof, J. N. Genomic analysis of circadian clock-, light-, and growth-correlated genes reveals PIF5 as a modulator of auxin signaling in Arabidopsis. Plant Physiol  (2011).  [http://dx.doi.org/10.1104/pp.111.172684]
*Jiménez-Gómez, J. M., Wallace, A. D. & Maloof, J. N. Network analysis identifies ELF3 as a QTL for the shade avoidance response in Arabidopsis. PLoS Genet 6,  (2010).  [http://dx.doi.org/10.1371/journal.pgen.1001100]
*Jimenez-Gomez, J. M. & Maloof, J. N. Sequence diversity in three tomato species: SNPs, markers, and molecular evolution. BMC Plant Biol 9, 85 (2009).  [http://dx.doi.org/10.1186/1471-2229-9-85]
*Filiault, D. L., Wessinger, C. A., Dinneny, J. R., Lutes, J., Borevitz, J. O., Weigel, D., Chory, J. & Maloof, J. N. Amino acid polymorphisms in Arabidopsis phytochrome B cause differential responses to light. Proc Natl Acad Sci U S A 105, 3157-3162 (2008).  [http://dx.doi.org/10.1073/pnas.0712174105]


<h3><font style="color:red">News</font></h3>
*2015-07-16: There is plenty of microbial life inside carnivorous plant traps [http://journal.frontiersin.org/article/10.3389/fmicb.2015.00526/abstract ...]
*2015-07-01: Kashif starts his PhD on stress induced chromatin changes.
*2015-06: Thomas leaving the lab, Henrich starting his masters and Catarine joining the group for one year of her PhD.
*2015-06: Ahmed and Phoebe defended their PhD work at University of Göttingen and Cologne, respectively. Congratulations!
*2015-06: Not only DNA demethylation - cytidine analog zebularine triggers DNA damage response in Arabidopsis. Read more in our recent Plant Cell paper [http://www.plantcell.org/content/early/2015/05/28/tpc.114.135467.full.pdf+html PDF]




*[[Maloof_Lab:Publications | see complete list...]]


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<h3><font style="color:#F8B603;">Announcements</font></h3>
 
*[[Maloof_Lab:Group_meeting|Group meeting, journal clubs, and seminars]]
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<h3><font style="color:red">Funding</font></h3>
 
*[http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5338&org=BIO NSF Plant Genome Research Program]
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**[http://www-plb.ucdavis.edu/Labs/sinha/TomatoGenome/ GEPR: Elucidating gene networks regulating development in tomato]
**[[Maloof_Lab:PGRP | Molecular evolutionary genetics of crop and weed responses to
crowding]] (2002-2008)
*[http://www.hfsp.org/ Human Frontier Science Program] (2004-2008)
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Revision as of 12:18, 21 August 2015


Home      Research      People      Publications      Protocols      Resources      Seminars      Positions      Lab life     


Research

The Pecinka lab is hosted by the Department of Plant Breeding and Genetics at the Max Planck Institute for Plant Breeding Research in Cologne, Germany.


Our goal is to understand molecular and evolutionary mechanisms shaping plant genomes and epigenomes. We analyze how DNA sequence and chromatin changes are generated by endo- and exogenous factors and how these forces are balanced by the genome repair and epigenetic mechanisms. To this end we use mainly the model plant Arabidopsis thaliana and several other Brassicaceae and analyze them by forward and reverse genetics, molecular, biochemical, cytogenetic and bioinformatic methods. read more...

Lab Members

Technitians


see complete list...



Recent Publications

  • Cao H.X., Schmutzer T, Scholz U, Pecinka A, Schubert I, Vu G.T.H. (2015): Metatranscriptome analysis reveals host-microbiome interactions in traps of carnivorous Genlisea species. Frontiers in Microbiology doi: 10.3389/fmicb.2015.00526 Open access
  • Liu C-H, Finke A, Diaz M, Rozhon W, Poppenberger B, Baubec T, Pecinka A. (2015): Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis. Plant Cell doi/10.1105/tpc.114.135467 Open access.
  • Baranauskė S, Mickutė M, Plotnikova A, Finke A, Venclovas Č, Klimašauskas S, Vilkaitis G. (2015): Functional mapping of the plant small RNA methyltransferase: HEN1 physically interacts with HYL1 and DICER-LIKE 1 proteins. Nucleic Acids Research 43:2802-2812 Full text
  • Willing, Rawat et al. (2015): Genome expansion of Arabis alpina linked with retrotransposition and reduced symmetric DNA methylation. Nature Plants 1:1-7 Full text

News

  • 2015-07-16: There is plenty of microbial life inside carnivorous plant traps ...
  • 2015-07-01: Kashif starts his PhD on stress induced chromatin changes.
  • 2015-06: Thomas leaving the lab, Henrich starting his masters and Catarine joining the group for one year of her PhD.
  • 2015-06: Ahmed and Phoebe defended their PhD work at University of Göttingen and Cologne, respectively. Congratulations!
  • 2015-06: Not only DNA demethylation - cytidine analog zebularine triggers DNA damage response in Arabidopsis. Read more in our recent Plant Cell paper PDF





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