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| |9/27/2012 | | |10/1/2013 |
| |Rosalie Sears | | | |
| |Organization | | |Organization |
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| |10/4/2012 | | |10/8/2013 |
| |Brittany Allen-Petersen | | | |
| |Tumourmicro-environment elicits innate resistance to RAF inhibitors through HGF secretion | | | |
| |[http://www.nature.com/nature/journal/v487/n7408/full/nature11183.html Straussman et al] | | | |
| |-- | | |-- |
| |10/11/2012 | | |10/15/2013 |
| |Ellen Langer | | | |
| |A restricted cell population propagates glioblastoma growth after chemotherapy | | | |
| |[http://openwetware.org/images/3/3a/Chen_Nature_2012.pdf Chen, et al] Additional vivo detection papers [http://www.ncbi.nlm.nih.gov/pubmed/22854777 1] [http://www.ncbi.nlm.nih.gov/pubmed/22855427 2]
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| |10/18/2012 | | |10/22/2013 |
| |Yulong Su | | | |
| |Transcriptional Amplification in Tumor Cells with Elevated c-Myc; | | | |
| c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
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| |[http://www.sciencedirect.com/science/article/pii/S0092867412010574 Lin 2012] | |
| [http://www.sciencedirect.com/science/article/pii/S0092867412011014 Nie 2012]
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| |10/25/2012 | | |10/29/2013 |
| |****CANCELLED**** Dr. Charles Lopez | | | |
| | Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer | | | |
| |[http://openwetware.org/images/a/a5/Nature11156.pdf Misale at. al] [http://openwetware.org/images/3/33/Nature11156-s1.pdf supp. info]
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| |11/1/2012 | | |11/5/2013 |
| |Asia Mitchell | | | |
| |Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks | | | |
| |[http://www.sciencedirect.com/science/article/pii/S0092867412004199] | | | |
| |-- | | |-- |
| |11/8/2012 | | |11/12/2013 |
| |Yuhan Wang | | | |
| |"Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Melanoma" | | | |
| |[http://openwetware.org/images/4/4e/Journal_Club_paper-5hmc.pdf] | | | |
| |-- | | |-- |
| |11/15/2012 | | |11/19/2013 |
| |Tyler Risom | | | |
| |Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer | | | |
| | [http://openwetware.org/images/8/85/PI3K_and_Parp_1.full.pdf Ashish et. al.] [http://openwetware.org/images/8/82/PI3K_and_Parp_2.full.pdf Yasir et al] | | | |
| |-- | | |-- |
| |11/22/2012 | | |11/26/2013 |
| |xxxxxxxxxx | | | |
| |THANKSGIVING, NO JOURNAL CLUB | | | |
| |xxxxxxxxxx | | | |
| |-- | | |-- |
| |11/29/2012 | | |12/3/2013 |
| |Dr. Swarnali Acharyya, a CDB/Knight faculty candidate seminar | | | |
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| |12/6/2012 | | |12/10/2013 |
| |Marilynn Chow | | | |
| |Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression | | | |
| |[http://openwetware.org/images/1/1d/2012_Oncogene_Pagliuca_et_al.pdf Pagliuca et al] [http://openwetware.org/images/3/3f/2012_Oncogene_Pagliuca_et_al_Supp.pdf supplement] | | | |
| |-- | | |-- |
| |1/10/2013 | | |12/17/2013 |
| |Lilli Welch | | | |
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| |-- | | |-- |
| |1/17/2013 | | |12/24/2013 |
| |Spencer Watson | | |Canceled |
| |Mitochondrial dynamics regulates migration and invasion of breast cancer cells | | | |
| |[http://openwetware.org/images/4/4b/Onc2012494a.pdf] | | | |
| |-- | | |-- |
| |1/24/2013 | | |12/31/2013 |
| |Ping Wang | | | |
| |Oncogenic Kras-Induced GM-CSF Projection Promotes the Development of Pancreatic Neoplasia | | | |
| |[http://www.ncbi.nlm.nih.gov/pubmed/22698407] [http://www.ncbi.nlm.nih.gov/pubmed/22698406] | | | |
| |-- | | |-- |
| |1/31/2013 | | |1/7/2014 |
| |Aaron Wortham | | | |
| |Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration | | | |
| |[http://openwetware.org/images/5/51/Luga_V_et_al_Cell_2012.pdf Luga V et al Cell 151, 1542-1556 (2012)] | | | |
| |-- | | |-- |
| |2/7/2013 | | |1/14/2014 |
| |Jeff Wu | | | |
| |MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrinsubunits | | | |
| | [http://www.nature.com/ncb/journal/v14/n6/pdf/ncb2491.pdf] | | | |
| |-- | | |-- |
| |2/14/2013 | | |1/21/2014 |
| |Tiffany Devine | | | |
| |The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites | | | |
| |[http://openwetware.org/images/3/3c/Gao_Cell_2012_BMP_inhibitor_coco_reactivates_BCC_at_lung_met_sites.pdf] | | | |
| |-- | | |-- |
| |2/21/2013 | | |1/28/2014 |
| |Ellie Juarez | | | |
| |Poly(beta-aminoester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo Molecular Cancer Therapeutics | | | |
| |[http://openwetware.org/images/b/bd/Gene_Therapy_JC_and_class.pdf] | | | |
| |-- | | |-- |
| |2/28/2013 | | |2/4/2014 |
| |Tim Butler | | | |
| |tumor heterogeneity, focusing mostly on a recent science paper (Kreso 2013) which shows serially passages clones responding differently to chemotherapy | | | |
| |[http://openwetware.org/images/0/09/Science-2013-Kreso-543-8.pdf Kreso 2013][http://openwetware.org/images/2/25/Gerlinger_2012%2C_Intratumor_Heterogeneity_multiregion_sequencing.pdf Gerlinger 2012] | | | |
| |-- | | |-- |
| |3/7/2013 | | |2/11/2014 |
| |Toni West | | | |
| |Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties | | | |
| |[http://openwetware.org/images/c/c3/Schwitalla_S_et_al_Cell_152%2C_25-38_%282013%29.pdf Schwitalla S et al Cell 152, 25-38 (2013)] | | | |
| |-- | | |-- |
| |3/14/2013 | | |2/18/2014 |
| |Jared Fischer | | | |
| |Intestinal label-retaining cells are secretory precursors expressing Lgr5 | | | |
| |[http://openwetware.org/images/0/09/Nature11965%281%29.pdf] | | | |
| |-- | | |-- |
| |3/21/2013 | | |2/25/2014 |
| |Mushui Dai | | | |
| |Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence. | | | |
| |[http://openwetware.org/images/5/57/2013_SRSF1_L5_p53_MC.pdf] | | | |
| |-- | | |-- |
| |4/4/2013 | | |3/4/2014 |
| |Nathalie Javidi-Sharifi | | | |
| |Tumor Stem Cells Generate Vasculature | | | |
| |[http://openwetware.org/images/2/25/Gsc_vasculature_hutchinson_comment_nature_2011.pdf] [http://openwetware.org/images/1/17/Gsc_pericytes_cheng_cell_2013_incl_supp.pdf] | | | |
| |-- | | |-- |
| |4/11/2013 | | |3/11/2014 |
| |Amy Farrell | | | |
| |Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer | | | |
| |[http://www.sciencedirect.com/science/article/pii/S1535610813000433 Stefan Eser, et al] | | | |
| |-- | | |-- |
| |4/18/2013 | | |3/18/2014 |
| |Trevor Levin | | | |
| |DNA damage foci formation around double strand breaks and regulation of NHEJ and HR repair mechanisms | | | |
| |[http://openwetware.org/images/5/59/Zimmermann2013_53BP1_Rif1_DSBRepair.pdf Zimmerman][http://openwetware.org/images/b/ba/Virgilio2013_Rif1_DNA_Breaks_IG_Switching.pdf Virgilio][http://openwetware.org/images/7/72/Kukas2013_Rif1_Perspective.pdf Kukas] | | | |
| |-- | | |-- |
| |4/25/2013 | | |3/25/2014 |
| |Kevin Watanabe-Smith | | | |
| |"Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models" | | | |
| |[http://openwetware.org/images/5/56/Corcoran_2013_Synthetic_Lethality_in_KRAS_mutant_cancer.pdf] [http://openwetware.org/images/6/68/Supplemental_-_Corcoran_2013.pdf] | | | |
| |-- | | |-- |
| |5/2/2013 | | |4/1/2014 |
| |Stacey Lin | | | |
| |Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion | | | |
| |[http://openwetware.org/images/a/ac/Li_and_Hanahan.pdf] | | | |
| |-- | | |-- |
| |5/9/2013 | | |4/8/2014 |
| |Juan Liang | | | |
| |Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53 | | | |
| |[http://openwetware.org/images/0/0e/2012_Cance_Cell_Inhibition_of_RNA_Polymerase_I_as_a_Therapeutic_Strategy.pdf] | | | |
| |-- | | |-- |
| |5/16/201 | | |4/15/2014 |
| |Xiaoxin Sun | | | |
| |Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP | | | |
| |[http://openwetware.org/images/5/5f/Cancer_journal_club_paper.pdf] | | | |
| |-- | | |-- |
| |5/23/2013 | | |4/22/2014 |
| |Dr. Charles Lopez | | | |
| |CANCELED DUE TO RESEARCH WEEK | | | |
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| |-- | | |-- |
| |5/30/2013 | | |4/29/2013 |
| |Mahnaz Janghorban | | | |
| |Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer | | | |
| |[http://openwetware.org/images/b/b2/Loss_of_FBP1_by_Snail-Mediated_Repression_Provides_Metabolic_Advantages_in_Basal-like_Breast_Cancer.pdf Dong et al] | | | |
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| | |5/6/2014 |
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| | |5/13/2014 |
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| | |5/20/2014 |
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| | |5/27/2014 |
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| | |6/3/2014 |
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| |6/6/2013 | | |6/10/2014 |
| |Marcus Calkins | | | |
| |The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation | | | |
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| |} | | |} |
| </div> | | </div> |