IGEM:Harvard/2006/DNA nanostructures: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
ShawnDouglas (talk | contribs) mNo edit summary |
|||
| (47 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
<div class="tabs-blue"> | |||
<ul> | |||
<li id="current">[[IGEM:Harvard/2006/DNA nanostructures|Project Overview]]</li> | |||
<li>[[IGEM:Harvard/2006/DNA_nanostructures/Designs|Designs]]</li> | |||
<li>[[IGEM:Harvard/2006/DNA_nanostructures/Notebook|Notebook]]</li> | |||
<li>[[IGEM:Harvard/2006/DNA_nanostructures/Protocols|Protocols]]</li> | |||
<li>[[IGEM:Harvard/2006/DNA_nanostructures/Presentations|Presentations]]</li> | |||
<li>[[IGEM:Harvard/2006/DNA_nanostructures/Literature|Literature]]</li> | |||
</ul> | |||
</div> | |||
<br style="clear:both"> | |||
==Project Overview== | ==Project Overview== | ||
*Our goal is | *Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus. | ||
*The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility. | *The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility. | ||
*As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers. | *As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers. | ||
| Line 12: | Line 25: | ||
**Cell sorting | **Cell sorting | ||
== | ==Working Team Members== | ||
[[ | *[[User:TChan|Tiffany Chan]] ([[User_talk:TChan|talk]], [[Special:Contributions/TChan|edits]]) | ||
*[[User:Kfifer|Katherine Fifer]] ([[User_talk:Kfifer|talk]], [[Special:Contributions/Kfifer|edits]]) | |||
*[[User:Vlau|Valerie Lau]] ([[User_talk:Vlau|talk]], [[Special:Contributions/Vlau|edits]]) | |||
*[[User:Matthewmeisel|Matthew Meisel]] ([[User_talk:Matthewmeisel|talk]], [[Special:Contributions/Matthewmeisel|edits]]) | |||
*[[User:Lhahn|Lewis Hahn]] ([[User_talk:Lhahn|talk]], [[Special:Contributions/Lhahn|edits]]) | |||
*TA: [[User:ShawnDouglas|Shawn Douglas]] ([[User_talk:ShawnDouglas|talk]], [[Special:Contributions/ShawnDouglas|edits]]) | |||
== | ==Recent Changes== | ||
{{Special:Recentchanges/b=IGEM:Harvard/2006/DNA_nanostructures/&limit=20}} | |||
= | |||
Latest revision as of 18:15, 28 October 2006
Project Overview
- Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
Working Team Members
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- Lewis Hahn (talk, edits)
- TA: Shawn Douglas (talk, edits)
Recent Changes
List of abbreviations:
- N
- This edit created a new page (also see list of new pages)
- m
- This is a minor edit
- b
- This edit was performed by a bot
- (±123)
- The page size changed by this number of bytes
