Harvard:SysBio 204/2014: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
No edit summary |
|||
(4 intermediate revisions by 2 users not shown) | |||
Line 20: | Line 20: | ||
*Instructors: George Church, William Shih, Pamela Silver, Peng Yin | *Instructors: George Church, William Shih, Pamela Silver, Peng Yin | ||
*Teaching Fellow: Evan Daugharthy | *Teaching Fellow: Evan Daugharthy | ||
*Meeting time: 2: | *Meeting time: 2:30 - 4:00 PM, Mon/Wed, Fall 2014 | ||
*Location: Room 521, Wyss Institute, 3 Blackfan circle, Boston, 02115 | *Location: Room 521, Wyss Institute, 3 Blackfan circle, Boston, 02115 | ||
*First class on Wednesday Sep 3rd. | *First class on Wednesday Sep 3rd. | ||
Line 74: | Line 74: | ||
==Recent changes== | ==Recent changes== | ||
{{Special:Recentchanges/b=Harvard:SysBio_204/2012&limit=50}} | {{Special:Recentchanges/b=Harvard:SysBio_204/2012&limit=50}} | ||
* Collaboration Policy added to [http://openwetware.org/wiki/Harvard:SysBio_204/2014:Final_Project_Presentations Midterm and Final Page] (8/27/14) |
Revision as of 12:10, 27 August 2014
Course overview
- A course focusing on the rational design, construction, and applications of nucleic acid and protein-based synthetic molecular and cellular machinery and systems. Students are mentored to produce substantial term projects.
- Intended for graduate students in Systems Biology, Biophysics, Engineering, Biology and related disciplines. No formal prerequisites. Projects are tailored to each student's strengths and interests.
- Website: http://sb204.net
- Poster
Midterm and Final
- There will be two midterms and one final project for this class
- Policy: strict submission deadline, we encourage you to submit your work the night before
- Midterm #1 due: October 2nd at noon
- Midterm #2 due: October 22nd
- Final project due: November 28
- Method of submission: email TA your slides and presentations
- Midterm and Final Projects (2013, to be updated)
Logistics
- Instructors: George Church, William Shih, Pamela Silver, Peng Yin
- Teaching Fellow: Evan Daugharthy
- Meeting time: 2:30 - 4:00 PM, Mon/Wed, Fall 2014
- Location: Room 521, Wyss Institute, 3 Blackfan circle, Boston, 02115
- First class on Wednesday Sep 3rd.
- Location: CLSB521
- No exams
- Prerequisites: none
- Grading
- 20% Participation
- 40% Midterm projects
- 40% Final project
- Harvard course site
Background Info and previous class projects
- BPH242r 2008-2009 http://openwetware.org/wiki/Biophysics_242r/2009 (Synthetic Biology)
- BPH242r 2010-2011 http://openwetware.org/wiki/Harvard:Biophysics_242r/2011 (Biologically Inspired Molecular Engineering)
- SB204 2011-2012 http://openwetware.org/wiki/Harvard:SysBio_204/2011
- SB204 2012-2013 http://openwetware.org/wiki/Harvard:SysBio_204/2012
- SB204 2013-2014 http://openwetware.org/wiki/Harvard:SysBio_204/2013
Example topics for final design project
- miRNA pattern recognition in eukaryotic cells
- Directed evolution of chemical sensors
- Nano-breadboards for probing electron transport in proteins
- Altered genetic codes and amino acid alphabets
- Modification of proteins for function in harsh environments
- Automatable assembly of large synthetic genes and circuits
- Synthetic biology of stem cells and epigenetic reprogramming pathways
- Structural re-engineering of adenoviruses
- Artificial chemotactic swimmers
- Nonequilibrium networks of nano-machines mimicking dynamic instability in the cytoskeleton
- Recombinase-based multi-state memory in bacteria
- Exosome manufacturing
- Self-assembled solar energy harvester based on bio-inorganic nano-antennae for uv-vis
- Systematic debugging of DNA labeling chemistries by atomic-resolution TEM imaging of DNA origami
- Transcriptional activation and repression through rational molecular design
- Tissue engineering scaffold nano-materials
- Programmable multistep chemical synthesis by templating on catalytic nanostructures
- Ultra-sensitive signal processing for synthetic biology
- Antibody 2.0
- Synthetic nanostructure - virus conjugates
- Replication of information in synthetic crystals
- Cheap large-scale production of protein or DNA-based materials
- Etc. Etc. Etc.
Recent changes
List of abbreviations:
- N
- This edit created a new page (also see list of new pages)
- m
- This is a minor edit
- b
- This edit was performed by a bot
- (±123)
- The page size changed by this number of bytes
25 April 2024
- Collaboration Policy added to Midterm and Final Page (8/27/14)