Imported:YPM/Ste4Ste18Ste5 Ste4Ste18Ste5 coop factor

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Category:Parameters - Yeast Pheromone Response Model Back to main model page

<modelParameter>Ste4Ste18Ste5_Ste4Ste18Ste5_coop_factor = </modelParameter>


This is the factor by which prior binding to of two Ste5 molecules to Ste4:Ste18 changes their dimerization affinity.
Kd_Ste4Ste18Ste5_Ste4Ste18Ste5 = Kd_Ste5_Ste5 / Ste4Ste18Ste5_Ste4Ste18Ste5_coop_factor
Ste4Ste18Ste5_Ste4Ste18Ste5_coop_factor > 1 means that prior binding of Ste4:Ste18 to Ste5 increases Ste5's dimerization affinity.


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Additional Details

See Ste4:Ste18/Ste5 interactions and Ste5 dimerization/oligomerization for more details.
See also Ste5 dimerization and Ste4 binding rate constant constraints.