User:Ilya/Yeast/Phylogeny/Candida glabrata

• pathogenic yeast of increasing medical concern [1]
• we find that genes involved in mating and meiosis are as numerous in C. glabrata as in the sexual species Kluyveromyces delphensis, which is its closest known relative. C. glabrata has a putative mating-type (MAT) locus and a pheromone gene (MFALPHA2), as well as orthologs of at least 31 other Saccharomyces cerevisiae genes that have no known roles apart from mating or meiosis, including FUS3, IME1 and SMK1. [1]

References

1. Wong S, Fares MA, Zimmermann W, Butler G, and Wolfe KH. Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata. Genome Biol. 2003;4(2):R10. DOI:10.1186/gb-2003-4-2-r10 |