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20.109 Research Proposal, WF Yellow Grouop
Find a 19S proteasome subunit protein that will bind a the Amaloid Beta protein responsible for Amaloid plaques in Alzheimer's disease and target it for degredation.
- Tania A. Baker and Robert T. Sauer. ATP-dependent proteases of bacteria: recognition logic and operating principles. TRENDS in Biochemical Sciences 2006; 31 (12) 647.