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Thinking of Simulation
1. Gillespie D. A general method for numerically simulating the stochastic time evolution of coupled chemical reactions [Internet]. Journal of computational physics. 1976 ;22(4):403–434.Available from: http://linkinghub.elsevier.com/retrieve/pii/0021999176900413
I am in the middle of reading this paper which is the introduction of his SSA. And i keep thinking that it probably won't be tough to make a simulation for a gliding motility assay. I am not sure how thorough i would make it. But i can make a distribution of kinesin on a cover slip, make their orientation distributed and then step each kinesin molecule on a microtubule through a monte carlo method that is described in the above paper. Possibly keep track of ATP, ADP, P. I don't think this is paper worthy because it must have been done before. I haven't found it since I have only been searching kinesin kinetics and not a bulk assay simulation like this. I have to run it by Koch, but i think i can do it. If it's worth my time is something different. Just writing it here so i don't forget it.