Larry Lok

I am a scientist at the Molecular Sciences Institute in Berkeley, CA. You can find more about me on this page.

I have taken a look at several papers connected with ODE parameter estimation, and written up some notes about them. Here are the papers themselves, including those that Koichi distributed:

• Kikuchi et al. 2003
• Moles, Mendes, and Banga, 2003
• Kimura et al. 2004
• Runarsson and Yao 2000
• Sugimoto et al. 2005

Here is an old write-up of a program to find time-varying input that maximizes the sensitivity of the response to a particular model parameter (a reaction rate as we discussed it previously.) This is the same genetic algorithm-type thing that Ty suggested long ago and which we have been talking about since Ty's simulation results that located such an input function.