User:Hussein Alasadi/Notebook/stephens/2013/10/16
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Jump to navigationJump to searchAnalyzing pooled sequenced data with selection  Main project page Previous entry 
Simulating evolution and then pooled sequencing
We can use Dick Hudson's MsSel (MS with selection) to generate a SNP distribution.
In MsSel, we can specify an allele frequency trajectory for a site. We can generate a trajectory based on a simple WF simulation with selection.
(1) draw a coverage (n) from [math] Pois(\lambda) [/math] where [math] \lambda \approx 4050 [/math] (2) [math] f_i [/math] (frequency of the ith SNP) ~ [math] B(n, f_i^{true}) [/math]
