Here is a list of different ideas I am going to pursue through the end of the semester.
- calculate force on single ferritin w/ magnetization
- conjugating ferritin to quantum dots
- fluorescent ferritin
- other types
- double check the "broken" yoke
- George Church
- Jeromy Edwards
- "salad dressing"
- Search through the literature
- resistance and current on electromagnet
- quantum dots: magnetic?
I was able to find a paper about fluorescent labeled ferritin. Here is link on ScienceDirect.
Some things that I learned:
- Ferritin has lysine and cysteine residues on the external surface that can be used for tags. The authors used the lysine to attache fluorophores.
- Adding the fluorophores increases the water solubility of the protein.
- Steve Koch 18:30, 22 April 2010 (EDT): Good find on this article! I, too, thought they claimed fluorophore increased water solubility, which seemed weird to me. Then upon reading the introduction, I think they mean that ferritin makes the iron oxide more soluble than just plain iron oxide. That would make sense, since ferritin is supposed to be a soluble protein, and lysine residues help with solubility.
- They mentioned something called a magnetometer with a SQUID sensor that I want to look up.
- The iron core was not altered by labeling the ferritin.