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[[BE_Board:Sean_Clarke | directory info]] | [[BE_Board:Sean_Clarke | directory info]] | ||
I am a | I am a second-year [http://web.mit.edu/be/ Biological Engineering] (BE, MIT Course XX) graduate student in the Alm lab (48-324). Our focus is on the evolution of microbial genomes, and I am specifically working on engineering genetic diversity and stress tolerance in ''Vibrio splendidus''. I hope to determine what alleles and loci contribute to environmental stress tolerance and whether these have analogues in the ocean environment. | ||
I | Along with [[Amy Nichols]], I am a coordinator of the [[BE Board | BE graduate student board]]. I was the first-year class representative last year, and am always happy to hear suggestions about improvements to the department. | ||
==Past life and credentials== | |||
My background is in mechanical engineering and design, but not of things quite as small as [[BioBricks]]. | |||
*B.S.M.E., [http://www.utexas.edu University of Texas at Austin], biomedical technical area | *B.S.M.E., [http://www.utexas.edu University of Texas at Austin], biomedical technical area | ||
*B.A., [http://www.utexas.edu University of Texas at Austin], Plan II Liberal Arts Honors Program | *B.A., [http://www.utexas.edu University of Texas at Austin], [http://www.utexas.edu/cola/progs/plan2/ Plan II] Liberal Arts Honors Program | ||
*Fulbright grant, Milan, Italy, independent study of industrial and engineering design methods, and classes in biomaterials at the [http://www.polimi.it Politecnico di Milano] | *Fulbright grant, Milan, Italy, independent study of industrial and engineering design methods, and classes in biomaterials at the [http://www.polimi.it Politecnico di Milano] | ||
I've also lived in Long Island, St. Louis, and Washington, DC, all of which I will defend and criticize passionately. | |||
== | ==Other research interests== | ||
*Engineering microbial stress tolerance | *Engineering microbial stress tolerance | ||
*Relating stress tolerance to genome loci | *Relating stress tolerance to genome loci | ||
*Resequencing evolved microbes | *Resequencing evolved microbes | ||
*Scaling of engineered biology | *Scaling of engineered biology to industrial purposes | ||
*Design and use of replicating biological machines | *Design and use of replicating biological machines | ||
*Technologies/vocabularies to make biological engineering easier | *Technologies/vocabularies to make biological engineering easier | ||
*Ethics and philosophy of science instruction for scientists/engineers | |||
*Biomimicry, bioscaffolds for material processing | *Biomimicry, bioscaffolds for material processing | ||
*Recycling/"cradle to cradle" design of biological systems | *Recycling/"cradle to cradle" design of biological systems | ||
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*BE.420 | *BE.420 | ||
*BE.430 | *BE.430 | ||
*[http://web.mit.edu/biophysics/sbio/ 7.81 Systems Biology] | *[http://web.mit.edu/biophysics/sbio/ 7.81 Systems Biology] Excellent class, Alex van Oudenaarden | ||
*[http://math.mit.edu/18085 18.085 Applied Math for Engineers] | *[http://math.mit.edu/18085 18.085 Applied Math for Engineers] with Gil Strang, who might have taught your parents, and is indefatigable, still revising his book daily. | ||
*[http://web.mit.edu/7.56 7.56 Graduate Cell Biology] | *[http://web.mit.edu/7.56 7.56 Graduate Cell Biology], with an emphasis on yeast, since that's what Stephen Bell and Frank Solomon work on. | ||
==Past Projects== | ==Past Projects== | ||
*My first project at MIT was the [[Orthogonal cloning of clpXP]] from ''E. coli'' into yeast. | *My first project at MIT was during the summer of 2005 when I tried the [[Orthogonal cloning of clpXP]] from ''E. coli'' into yeast. I was more successful at learning molecular biology and techniques by making mistakes than at cloning into yeast. This work is continuing in someone else's more capable hands. |
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