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IGEM:Paris Bettencourt 2012/Previous Biosafety iGEM Projects: Difference between revisions
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IGEM:Paris Bettencourt 2012/Previous Biosafety iGEM Projects (view source)
Revision as of 08:23, 12 September 2012
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| Engineering C.elegans for advanced bioremediation | | Engineering C.elegans for advanced bioremediation | ||
| '''''Kill switch.''''' | | '''''Kill switch.''''' | ||
#''''' | #'''''MRT-2 mutant Kill Switch''''' | ||
:This is an indirect kill switch. The teams plans to use a mutant strain of bacteria which has losts its molecules for immortality. It can reproduce for only a couple generation and will then become sterile, leading to the extinction of this bacteria population. | :This is an indirect kill switch. The teams plans to use a mutant strain of bacteria which has losts its molecules for immortality. It can reproduce for only a couple generation and will then become sterile, leading to the extinction of this bacteria population. | ||
#''''' | #'''''RNAi Kill Switch''''' | ||
:RNAi knockout is a method of gene regulation where double stranded RNA (dsRNA) is introduced to the worm, binding to gene products such as specific RNAs (mRNA), thereby decreasing or eradicating RNA activity by recycling said products. Only a few dsRNA molecules per cell are required to produce effective interference. | |||
<p style="text-align:right;"> [http://2011.igem.org/Team:Queens_Canada/Side/KillSwitch Read More] </p> | <p style="text-align:right;"> [http://2011.igem.org/Team:Queens_Canada/Side/KillSwitch Read More] </p> | ||
|#''''' | | | ||
#'''''MRT-2 mutant Kill Switch''''' | |||
:"Given that the germ-line of the mrt-2 mutant has a limited number of generations in which it can reproduce, our created strain is timed for eventual extinction of a span between 2 months and 1 year, with the average being 6.25 months". However, no experiment is provided, and so we do not know how they obtained these numbers, but we could assume they come from the literature. | :"Given that the germ-line of the mrt-2 mutant has a limited number of generations in which it can reproduce, our created strain is timed for eventual extinction of a span between 2 months and 1 year, with the average being 6.25 months". However, no experiment is provided, and so we do not know how they obtained these numbers, but we could assume they come from the literature. | ||
#''''' | #'''''RNAi Kill Switch''''' | ||
: No results | |||
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