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CH391L/S12/Selectablegeneticmarkers: Difference between revisions
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==Artificial Selection== | ==Artificial Selection== | ||
Selectable markers have a remarkably relevant role in industrial applications. Because of their ability to distinguish cells from one another, selectable markers are an essential tool for artificial selection. While artificial selection of organisms is possible without the use of selectable markers, the process is significantly shorter with their use. | Selectable markers have a remarkably relevant role in industrial applications. Because of their ability to distinguish cells from one another, selectable markers are an essential tool for artificial selection. While artificial selection of organisms is possible without the use of selectable markers, the process is significantly shorter with their use. | ||
Artificial selection is a special instance in which selectable markers are often the desired gene to be introduced into a cell. For instance, rice has been transfected with a plethora of resistances using selectable markers. Glycopeptide binding protein, dihydrofolate reductase, and hygromycin phosphotransferase have all been introduced into rice, conferring resistance to bleomycin and pheomycin, methotrexate, and hygromycin B respectively<cite>Twyman2002</cite>. | |||
==Issues== | ==Issues== | ||
===Genetically Modified Organisms=== | ===Genetically Modified Organisms=== | ||
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#Chalfie1994 pmid=8303295 | #Chalfie1994 pmid=8303295 | ||
//The first instance of using GFP as a marker. | //The first instance of using GFP as a marker. | ||
#Twyman2002 pmid=1282647 | |||
// | |||
</biblio> | </biblio> | ||
