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User:Despaux: Difference between revisions
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My research concerns nucleic acids as adaptive gene regulatory elements in mammalian cells. These molecules are able to detect changes in the cellular environment, e.g. cancerous or infected, and act accordingly. I'm currently designing and testing RNA molecules to efficiently knock down genes in cancerous cells but not in normal cells. Previously I've worked on human genetic evolution, drug delivery, tissue engineering, novel nucleic acids, and macromolecular transport across nuclear pores. | My research concerns nucleic acids as adaptive gene regulatory elements in mammalian cells. These molecules are able to detect changes in the cellular environment, e.g. cancerous or infected, and act accordingly. I'm currently designing and testing RNA molecules to efficiently knock down genes in cancerous cells but not in normal cells. Previously I've worked on human genetic evolution, drug delivery, tissue engineering, novel nucleic acids, and macromolecular transport across nuclear pores. | ||
Department of Chemical Engineering, California Institute of Technology, 9/2005–present</ | Department of Chemical Engineering, California Institute of Technology, 9/2005–present<br/> | ||
Advisor: Christina Smolke</ | Advisor: Christina Smolke<br/> | ||
Ligand-dependent control of gene expression through non-coding RNA | Ligand-dependent control of gene expression through non-coding RNA | ||
Howard Hughes Medical Institute, The Rockefeller University, 6/2005–9/ | Howard Hughes Medical Institute, The Rockefeller University, 6/2005–9/<br/> | ||
Advisor: [Günter Blobel]</ | Advisor: [Günter Blobel]<br/> | ||
Purification and characterization of nuclear membrane complex proteins | Purification and characterization of nuclear membrane complex proteins | ||
Department of Biological Engineering, Cornell University, 1/2002–5/2005</ | Department of Biological Engineering, Cornell University, 1/2002–5/2005<br/> | ||
Advisor: Dan Luo</ | Advisor: Dan Luo <br/> | ||
Synthesis and design of DNA-based, self-assembled nanoscale structures | Synthesis and design of DNA-based, self-assembled nanoscale structures | ||
School of Chemical Engineering, Cornell University, 9/2001 – 5/2002</ | School of Chemical Engineering, Cornell University, 9/2001 – 5/2002<br/> | ||
Advisor: W. Mark Saltzman</ | Advisor: W. Mark Saltzman<br/> | ||
Tissue engineering and polymer-based drug delivery | Tissue engineering and polymer-based drug delivery | ||
Department of Biology, Florida International University, 6/2000 | Department of Biology, Florida International University, 6/2000–11/2000<br/> | ||
Advisor: René Herrera</ | Advisor: René Herrera<br/> | ||
Human genetic evolution | Human genetic evolution | ||
==Publications== | ==Publications== | ||
# “Controlled assembly of dendrimer like DNA”, Y. Li, Y.D. Tseng, S.Y. Kwon, L. d'Espaux, J.S. Bunch, P.L McEuen, and D. Luo, ''Nature Materials'' '''3''', 38-42, (January, 2004) [http://www.its.caltech.edu/~despaux/papers/Luo-naturematerials2004.pdf] | # “Controlled assembly of dendrimer like DNA”, Y. Li, Y.D. Tseng, S.Y. Kwon, L. d'Espaux, J.S. Bunch, P.L McEuen, and D. Luo, ''Nature Materials'' '''3''', 38-42, (January, 2004) [http://www.its.caltech.edu/~despaux/papers/Luo-naturematerials2004.pdf] | ||
# “Honeycomb-shaped DNA”, L. d’Espaux, and D. Luo, ''Proceedings of the 18th Annual Cornell Undergraduate Research Board Forum'', 69 (March, 2002) | # “Honeycomb-shaped DNA”, L. d’Espaux, and D. Luo, ''Proceedings of the 18th Annual Cornell Undergraduate Research Board Forum'', 69 (March, 2002) | ||
