Ampicillin: Difference between revisions

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==Mechanism of Resistance==
==Mechanism of Resistance==


Expression of beta-lactamase neutralizes ampicillin.  When this enzyme  
Expression of [[β-lactamase]] neutralizes ampicillin.  When this enzyme is expressed on a high-copy number plasmid there is significant diffusion into the extracellular medium.  As a result non-resistant satellite colonies may form around larger resistant colonies.
 
(would be nice to have a picture of this here)


==References==
==References==
Molecular Cloning: A Laboratory Manual, Vol 1.
Molecular Cloning: A Laboratory Manual, Vol 1.
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