User:Brendan J. Hussey: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
No edit summary
No edit summary
Line 12: Line 12:
<!--Include info about your educational background-->
<!--Include info about your educational background-->
* 2010, BSc Honors Molecular Biology & Genetics, Minor Neuroscience, University of Guelph
* 2010, BSc Honors Molecular Biology & Genetics, Minor Neuroscience, University of Guelph
*Currently looking for grad school opportunities in synthetic biology in my interest areas


==Synthetic Biology Experience==
==Synthetic Biology Experience==
#Awarded Bronze metal in iGEM 2008 representing the University of Guelph with goal of engineering food grade bacteria to produce beta-carotene. Proof of concept completed in E.coli.  
* Awarded Bronze metal in iGEM 2008 representing the University of Guelph with goal of engineering food grade bacteria to produce beta-carotene. Proof of concept completed in E.coli.  


==Interests==
==Interests==
Line 20: Line 21:


===Synthetic Biology===
===Synthetic Biology===
# Genetic manipulation/rational design of symbiotic bacteria for therapeutic purposes; elaborating host/microbe interactions, controlled drug delivery, etc.
* Genetic manipulation/rational design of symbiotic bacteria for therapeutic purposes; elaborating host/microbe interactions, controlled drug delivery, etc.
# Organelle-like, compartmentalized isolation of select metabolic components for introducing modularity and increasing pathway efficiency.
* Organelle-like, compartmentalized isolation of select metabolic components for introducing modularity and increasing pathway efficiency.
# Harnessing cellular energy for powering electronics
* Harnessing cellular energy for powering electronics
# Reliable, targeted gene manipulation in eukaryotes (gene therapy).
* Reliable, targeted gene manipulation in eukaryotes (gene therapy).


===Other Interests===
===Other Interests===
# Epigenetics: particularly of neuroplasticity.  
* Epigenetics: particularly of neuroplasticity.  
# Brain-machine interfaces
* Brain-machine interfaces
# IPSC's: everything.
* IPSC's: everything.


==Favorite Synthetic Biology Related Publications==
==Favorite Synthetic Biology Related Publications==
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
<biblio>
<biblio>
#coolpmid pmid=18607005
#coolpmid pmid=18607005.
 
#coolpmid pmid=15064770.
#coolpmid pmid=19177133.
#coolpmid pmid=19648908.
#coolpmid pmid=19693014.
#coolpmid pmid=19563759.
</biblio>
</biblio>



Revision as of 00:28, 24 February 2010

Contact Info

Brendan J. Hussey (an artistic interpretation)
  • Brendan J. Hussey
  • University of Guelph
  • Guelph, Ontario, Canada.
  • bjohnhussey@gmail.com

I work in the OVC Pathobiology department at Guelph University. I learned about OpenWetWare from iGEM and Andrew Hessel, and I've joined because Competing in iGEM secured strong interest in synthetic biology; intend of pursuing career in this area.

Education

  • 2010, BSc Honors Molecular Biology & Genetics, Minor Neuroscience, University of Guelph
  • Currently looking for grad school opportunities in synthetic biology in my interest areas

Synthetic Biology Experience

  • Awarded Bronze metal in iGEM 2008 representing the University of Guelph with goal of engineering food grade bacteria to produce beta-carotene. Proof of concept completed in E.coli.

Interests

Synthetic Biology

  • Genetic manipulation/rational design of symbiotic bacteria for therapeutic purposes; elaborating host/microbe interactions, controlled drug delivery, etc.
  • Organelle-like, compartmentalized isolation of select metabolic components for introducing modularity and increasing pathway efficiency.
  • Harnessing cellular energy for powering electronics
  • Reliable, targeted gene manipulation in eukaryotes (gene therapy).

Other Interests

  • Epigenetics: particularly of neuroplasticity.
  • Brain-machine interfaces
  • IPSC's: everything.
  1. Tabor JJ, Salis HM, Simpson ZB, Chevalier AA, Levskaya A, Marcotte EM, Voigt CA, and Ellington AD. A synthetic genetic edge detection program. Cell. 2009 Jun 26;137(7):1272-81. DOI:10.1016/j.cell.2009.04.048 | PubMed ID:19563759 | HubMed [coolpmid]
  2. Ryan RM, Green J, Williams PJ, Tazzyman S, Hunt S, Harmey JH, Kehoe SC, and Lewis CE. Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors. Gene Ther. 2009 Mar;16(3):329-39. DOI:10.1038/gt.2008.188 | PubMed ID:19177133 | HubMed [coolpmid]
  3. You L, Cox RS 3rd, Weiss R, and Arnold FH. Programmed population control by cell-cell communication and regulated killing. Nature. 2004 Apr 22;428(6985):868-71. DOI:10.1038/nature02491 | PubMed ID:15064770 | HubMed [coolpmid]
  4. Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlman B, and Hahn KM. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature. 2009 Sep 3;461(7260):104-8. DOI:10.1038/nature08241 | PubMed ID:19693014 | HubMed [coolpmid]
  5. Dueber JE, Wu GC, Malmirchegini GR, Moon TS, Petzold CJ, Ullal AV, Prather KL, and Keasling JD. Synthetic protein scaffolds provide modular control over metabolic flux. Nat Biotechnol. 2009 Aug;27(8):753-9. DOI:10.1038/nbt.1557 | PubMed ID:19648908 | HubMed [coolpmid]
  6. Kong W, Wanda SY, Zhang X, Bollen W, Tinge SA, Roland KL, and Curtiss R 3rd. Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9361-6. DOI:10.1073/pnas.0803801105 | PubMed ID:18607005 | HubMed [coolpmid]

All Medline abstracts: PubMed | HubMed