IGEM:Stanford/2009/Notebook/Marys iGEM Notebook/2009/08/17
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Modeling on the Wild Type Tryptophan Gene Regulatory System
Below are the several critical equations we use in this model:
Base on the fitting to Fig 1 from Reference , we came to the result kT=1.62e4 molecules/cell. While the kT measured by Schmitt et al. (1995) is 1.97e4 molecules/cell. The figure below shows the result of our fitting, and the comparison to standard kT value.
Thus, it is reasonable to calculate k_T values for trp with mutant repressor, 5MT with wildtype repressor, and MT with mutant repressor.