Biomod/2014/UANL/enzimas

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<html> <head> <title>Enzimas</title> </head> <body> <p style="text-align: center;"><span style="font-size:28px;"><u>Enzimas</u></span></p>

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<p><span style="font-size:20px;"><u>Introduccion (peque&ntilde;a explicacion)</u></span></p>

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<p><span style="font-size:20px;"><u>Uricasa&nbsp;</u></span></p>

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<p>Propiedades( Temperatura de transicion ,medios a los que sobrevive , tama&ntilde;o ,etc)</p>

<p>Reactividad ( cross linking , sitios activos , etc )&nbsp;</p>

<p>MSDS ( ficha tecnica )</p>

<p>Uricase (<a href="http://www.ebi.ac.uk/intenz/query?cmd=SearchEC&amp;ec=1.7.3.3">EC:1.7.3.3</a>) (urate oxidase) [<a href="http://europepmc.org/abstract/MED/3182808">PMID: 3182808</a>] is the peroxisomal enzyme responsible for the degradation of urate into allantoin:&nbsp;Urate + O<sub>2</sub>&nbsp;+ H<sub>2</sub>O = 5-hydroxyisourate + H<sub>2</sub>O<sub>2</sub>&nbsp;Some species, like primates and birds, have lost the gene for uricase and are therefore unable to degrade urate [<a href="http://europepmc.org/abstract/MED/2594778">PMID: 2594778</a>]. Uricase is a protein of 300 to 400 amino acids, its sequence is well conserved. It is mainly localised in the liver, where it forms a large electron-dense paracrystalline core in many peroxisomes [<a href="http://europepmc.org/abstract/MED/2338140">PMID: 2338140</a>]. The enzyme exists as a tetramer of identical subunits, each containing a possible type 2 copper-binding site [<a href="http://europepmc.org/abstract/MED/2594778">PMID: 2594778</a>]. In legumes, 2 forms of uricase are found: in the roots, the tetrameric form; and, in the uninfected cells of root nodules, a monomeric form, which plays an important role in nitrogen-fixation [<a href="http://europepmc.org/abstract/MED/16593585">PMID: 16593585</a>].</p>

<p><strong>Bibliograf&iacute;a</strong><strong> </strong></p>

<p>http://www.ebi.ac.uk/interpro/IEntry?ac=IPR019842</p>

<p><u>http://www.msdshazcom.com/MSDS/G/genzyme/Uricase-Arthrobacter%20sp..pdf</u></p>

<p><span style="font-size:20px;"><u>Ureasa</u></span></p>

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<p>Propiedades( Temperatura de transicion ,medios a los que sobrevive , tama&ntilde;o ,etc)</p>

<p>Reactividad ( cross linking , sitios activos , etc )&nbsp;</p>

<p>MSDS ( ficha tecnica )</p>

<div><span style="font-size:20px;"><u>Catalasa</u></span></div>

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<p>Propiedades( Temperatura de transicion ,medios a los que sobrevive , tama&ntilde;o ,etc)</p>

<p>Reactividad ( cross linking , sitios activos , etc )&nbsp;</p>

<p>MSDS ( ficha tecnica )</p>

<p>&nbsp;</p> </body> </html>