|
|
| (23 intermediate revisions by the same user not shown) |
| Line 25: |
Line 25: |
| <div style="padding: .4em .9em .9em"> | | <div style="padding: .4em .9em .9em"> |
| [[X-Lab|Home]]|[[X-Lab|主页]] | | [[X-Lab|Home]]|[[X-Lab|主页]] |
| | ---- |
| | [[X:News|News]]|[[X:新闻动态|新闻动态]] |
| ---- | | ---- |
| [[X:Research|Research]]|[[X:研究|研究]] | | [[X:Research|Research]]|[[X:研究|研究]] |
| ---- | | ---- |
| [[X:People|People]]|[[X:成员|成员]] | | <!--{[[X:People|People]]|[[X:成员|成员]]--> |
| | [[X:People|People]] |
| ---- | | ---- |
| [[X:Publications|Publications]]|[[X:发表|发表]] | | [[X:Publications|Publications]]|[[X:发表|发表]] |
| Line 37: |
Line 40: |
| ---- | | ---- |
| [[X:Links|Links]]|[[X:链接|链接]] | | [[X:Links|Links]]|[[X:链接|链接]] |
| | ---- |
| | [[X:Internal|Internal]]|[[X:内部|内部]] |
| ---- | | ---- |
| [[X:Contact|Contact]]|[[X:联系|联系]] | | [[X:Contact|Contact]]|[[X:联系|联系]] |
| Line 49: |
Line 54: |
| </font> | | </font> |
|
| |
|
| <font face="Helvetica" size=3> | | <font face="Helvetica" size=4> |
|
| |
|
|
| |
|
| LAB DESCRIPTION | | LAB DESCRIPTION |
|
| |
|
| Our lab is broadly interested in transmembrane and sensory signaling based on channels, pursuing both biophysical mechanisms and bioengineering innovations.
| | The central focus of our lab is ion channels, the third largest superfamily of signaling proteins. We are particularly attracted by the amazing capabilities of ion channels in sensing exogenous stimuli of diverse modality, such as transmembrane potentials, ionic signals, mechanical forces and electromagnetic radiations. '''How exactly would ion channels sense, transduce and process the stimuli (i.e., energy and information) at submolecular, molecular and cellular levels?''' Based on these core biophysics, we pursue mechanistic understanding, pathophysiological ramifications and bioengineering innovations, of transmembrane signaling via ion channels, especially those related to sensory functions, including vision, taste, hearing and other less-studied modalities. |
|
| |
|
| One of the most important signaling pathways to convey information from external world into biological systems is by way of channels sitting across the membrane. Such channels: could be cued either by physical (e.g. voltage or photons) or by chemical signals (e.g. toxins or ions); could be either natural channels (e.g. ion channels conductive to Ca<sup>2+</sup> or K<sup>+</sup>) or engineered channels (e.g., nanopores by ultrasound). We mainly focus on fundamental mechanisms critical to channel complexes involved in transmembrane signaling, especially those related to sensory functions, such as vision, taste, hearing and other less-studied modalities. Representative work toward this direction refers to [http://www.nature.com/nature/journal/v463/n7283/full/nature08766.html '''Liu X.''' ''et. al.'' '''Nature''']. Meanwhile, we actively explore the potentials of novel methodologies developed or derived from our basic research, such as sonoporation, channel modulators, biomolecular sensors etc. [http://openwetware.org/wiki/User:Xiaodong_Liu#Publications relevant publications]
| |
|
| |
|
|
| |
|
| Line 62: |
Line 66: |
|
| |
|
|
| |
|
| | <font face="Helvetica" size=6> |
|
| |
|
| | | [[X:BS20013|Attention: 刘晓冬研究组（X-LAB）本科生研究课题]] |
| == Lab News ==
| |
| | |
| '''Opening Positions of X-Lab: starting to accept applications from Nov. 2011 until filled'''
| |
|
| |
| http://talent.sciencenet.cn/info.aspx?id=11325
| |
| | |
| | |
| | |
| '''X-Lab Students attended Tsinghua BoShiShen Symposium of Medical School, Nov 19, 2011, Beijing'''
| |
| | |
| JIANG Peng (Prize for Excellent Oral Talks)
| |
| | |
| LIU Nan, et al. (Poster)
| |
| | |
| TANG Ji, et al. (Poster)
| |
| | |
| | |
| | |
| '''JIANG Peng from X-Lab received "excellent poster award" at 17th “International Biophysics Congress” (IAPUB) Oct 30-Nov 3 Beijing, China
| |
| '''
| |
| See also, [http://bme.med.tsinghua.edu.cn/index.php?option=com_content&task=view&id=482&Itemid=90 BME Departmental News]
| |
| | |
| Congratulations, Peng!
| |
| | |
| | |
| '''LIU Xiaodong presented X-Lab research as an invited talk at Asia Communications and Photonics Conference (ACP2011), Nov. 13-16, 2011, Shanghai
| |
| '''
| |
| | |
| | |
| | |
| '''JIANG Peng from X-Lab presented research at Tsinghua BoShiShen Symposium of Life and Biomedical Sciences, Oct 15-16, 2011, Beijing
| |
| '''
| |
| | |
| | |
| | |
| [[Image:JIANGPeng2011.jpg|thumb|left|100x100px]] | |
| | |
| {{-}}
| |
| | |
| | |
| '''X-Lab presented research at CaBP17, July 17-20, 2011, Beijing
| |
| '''
| |
| | |
| LIU Nan ''et al.''(poster)
| |
| | |
| XU Yanyan ''et al.'' (poster)
| |
| | |
| LIU Xiaodong （invited talk)
| |
| | |
| | |
| | |
| '''The X-lab is starting to accept PTN students for research rotations!'''
| |
| | |
| http://life.tsinghua.edu.cn/home/announce/1613.html
| |
| | |
| http://www.nibs.ac.cn/?act=view&id=2741
| |
| | |
|
| |
| | |
| '''Postdoctoral Position Openings'''
| |
| http://www.nature.com/naturejobs/science/jobs/191089-Postdoctoral-Fellow-Tsinghua-University
| |
| | |
| | |
| | |
| '''X-Lab (LIU Qing, XIE Xin and LIU Xiaodong) presented the poster:
| |
| | |
| CHARACTERIZATION OF QUANTITATIVE FRET SENSORS FOR FLUORESCENCE MOLECULAR TOMOGRAPHY'''
| |
| | |
| Author Block: Qing Liu, Xin Xie, Yi Zhang, Yanyan Xu, Yue Zhang, Xin Liu, Jing Bai, Xiaodong Liu.
| |
| | |
| Tsinghua University, Beijing, China.
| |
| | |
| during Biophysics Society Annual Meeting, March 2011 at Baltimore, MD, USA
| |
| | |
| == Updates ==
| |
| | |
| | |
| Individual Meetings (Starting from 2011/10)
| |
| | |
| | |
| <!--
| |
| [[Image:MeetingsXLab201108.jpg|thumb|left|800x300px|X-LAB Schedule]]
| |
| -->
| |
| | |
| | |
| | |
| 17th “International Biophysics Congress” (IAPUB) Oct 30-Nov 3 Beijing, China
| |
| | |
| http://www.17ibc.org/
| |
| | |
| | |
| | |
| 55th Annual Meeting of Biophysical Society March 5 - 9, 2011
| |
| | |
| http://www.biophysics.org/2012meeting
| |
| | |
| <font face="Helvetica" size=4>
| |
| | |
| <!--
| |
| Journal Club (Jointed with DU Lab and SONG Lab)
| |
| -->
| |
| | |
| | |
| | |
| </font><br>
| |
| | |
| <!--== 2010 ==
| |
| | |
| | |
| ZHANG Yue 8/12 FRET-based FMT
| |
| | |
| XU Yanyan 9/10 GPCR/Sensory Neuron
| |
| | |
| ZHAO Shan (from Du Lab) 9/25 Remotely Triggerable Drug Delivery Systems
| |
| | |
| LIU Qing 10/15 reversible photoswitchable rsTagRFP for pcFRET
| |
| | |
| YU Tao (from Song Lab) 10/22 Tetracycline-regulatable factors with distinct dimerization
| |
| domains allow reversible growth inhibition by p16
| |
| | |
| TSE Yan Franco (XIE Xin) 10/29 Calcium Channels
| |
| | |
| NIU Pengxia (from DU Lab) 11/5 fuorescent structural DNA nanoballs functionalized with phsphate-linked nuceotide triphosphates
| |
| | |
| LI Xuesong (from SONG Lab) 11/19 global and local fmri signals driven by neurons defined optogenetically by type and writing
| |
|
| |
| Claudia Wittkowske (from DU Lab) 11/26 "Glioblastoma stem-like cells give rise to tumour endothelium"
| |
| | |
| XUE Wenwen 12/10 bacteria magnetosome
| |
| | |
| YU Tao (from SONG Lab) 12/17 optical dimerization
| |
| | |
| XU Yanyan 12/24 Functional connectivity in the retina at the resolution of photoreceptors
| |
| -->
| |
| | |
| <!--== 2011 ==
| |
| | |
| | |
| ZHAO Shan (from Du Lab) 1/7 Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones
| |
| | |
| LI Xuesong (from SONG Lab) 2/25 "Genetic dissection of an amygdala microcircuit that gates conditioned fear" and "Encoding of conditioned fear in central amygdala inhibitory circuits"
| |
| | |
| LIU Nan 3/28 Salty Taste
| |
| | |
| | |
| {{-}}
| |
| | |
| [[Image:X.png|thumb|left|400x400px|X-LAB. ]]
| |
| | |
| {{-}}
| |
| | |
| ---------------------------------------------------
| |
| <font face="Helvetica" size=3>
| |
| <br>The following positions are currently available:
| |
| | |
| '''Postdoctoral Fellows'''
| |
| | |
| | |
| | |
| '''Ph.D. Students'''
| |
| | |
| '''Masters' Students'''
| |
| | |
| Please send email to [mailto:liuX.tsinghua@gmail.com Dr. Liu] if you are interested. Include your CV and a brief description of your career goals.
| |
| | |
| We also welcome '''undergraduate students''' (especially from major research universities in Beijing) to conduct research in our lab on thesis projects.
| |
| | |
| All above positions can start immediately.
| |
| | |
| | |
| | |
| | |
|
| |
|
| </font> | | </font> |
| -->
| |
