Difference between revisions of "Veit-Simon Eckle"

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Revision as of 08:29, 6 February 2013

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Dr. Veit-Simon Eckle

Waldhörnlestr. 22
D-72072 Tübingen
Tel. ++49-7071/7 93 62 17
Fax ++49-7071/36 51 09

Residency: Department of Anesthesiology, University of Tübingen

Department of Anesthesiology, Klinikum rechts der Isar, Munich
Department of Anesthesiology, Brüderkrankenhaus Trier

Fellowship: Research Associate, Department of Anesthesiology (Prof. SM. Todorovic, Todorovic Lab) and Pharmacology (Prof. E. Perez Reyes Perez-Reyes Lab), University of Virginia, Charlottesville, Virginia, USA
Research Interests: Anesthetic effects on molecular targets in neuronal networks, GABAA and glycine receptors, voltage-gated Ca2+ channels (T-type), two-pore-potassium channels (TREK), spinal cord
Methods: Current clamp recordings in cell-attached and whole-cell mode, voltage clamp recordings, inside-out-configuration, cultured spinal neurons, brain slice technique
Awards: 3rd Prize, oral presentation competition: "Propofol modulates rather phasic than tonic GABAergic currents in the spinal ventral horn", 14th Capital City Conference of the DGAI, Congress of Anesthesiology and Intensive Care Medicine, September 2012

WAKWIN Mentee, German Society for Anaesthesiology and Intensive Care, 2010
Resident Travel Award, SNACC Meeting, Orlando 2008

Patent: Intrajugular balloon catheter for prevention of air embolism (DE102011106676.8)
Professional Societies: German Society for Anaesthesiology and Intensive Care
European Society of Anaesthesiology

Selected Publications:

  • Eckle VS, Digruccio MR, Uebele VN, Renger JJ, Todorovic SM. Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane. Neuropharmacology. 2012 Aug;63(2):266-73 PubMed
  • Eckle VS, Grasshoff C. Intrajugular balloon catheter for prevention of air embolism. J Neurosurg Anesthesiol. 2012 Jan;24(1):81-2. PubMed
  • Choe W, Messinger RB, Leach E, Eckle VS, Obradovic A, Salajegheh R, Jevtovic-Todorovic V, Todorovic SM. TTA-P2 is a potent and selective blocker of T-type calcium channels in rat sensory neurons and a novel antinociceptive agent. Mol Pharmacol. 2011;80:900-10. PubMed
  • Eckle VS, Todorovic SM. Mechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcohols. Neuropharmacology. 2010;59:58-69. PubMed
  • Eckle VS, Hucklenbruch C, Todorovic SM. What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia. Anaesthesist. 2009 Nov;58(11):1144-9. PubMed
  • Haseneder R, Kratzer S, Kochs E, Eckle VS, Zieglgänsberger W, Rammes G. Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala. Anesthesiology. 2008;109:998-1006. PubMed
  • Eckle VS, Buchmann A, Bursch W, Schulte-Hermann R, Schwarz M. Immunohistochemical detection of activated caspases in apoptotic hepatocytes in rat liver. Toxicol Pathol. 2004;32:9-15. PubMed