Van Oudenaarden Lab

From OpenWetWare
Revision as of 09:39, 24 December 2007 by Alexander (talk | contribs)
Jump to: navigation, search
Alexander van Oudenaarden

Welcome to the van Oudenaarden Lab homepage, hosted by OpenWetWare. Also check out our other lab web-site


Phone: (617) 253-4446

Fax: (617) 258-6883


77 Massachusetts Ave.

Bldg. 68-371B (Office)

Bldg. 68-365, 68-359, 68-383 (Labs)

Cambridge, MA 02139


Living systems are intrinsically noisy. Surprisingly, the functioning of a living organism is not significantly hindered by these random fluctuations. Biological cells can even exploit noise by deliberately introducing diversity into a population. In these cases noise is not a nuisance, but essential for survival. Advances in modern biochemistry and genetics have led to a detailed understanding of the molecular machinery involved in gene expression, and the constant flow of data from the Genome Project has enabled the identification of more and more genes. A millennial challenge is to quantitatively understand how different genes and their regulating proteins are grouped together in genetic circuits, and how stochastic fluctuations influence gene expression in these complex systems. In our group we focus on the importance of noise in the expression of genes by using both experimental and theoretical approaches.

Recent Publications

For our recent publications see

...all publications

Lab members

Internal lab resource