Difference between revisions of "Van Oudenaarden Lab"

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[[Image:alexander_van_oudenaarden.jpg|frame|Alexander van Oudenaarden]]
 
[[Image:alexander_van_oudenaarden.jpg|frame|Alexander van Oudenaarden]]
Welcome to the Movileanu Lab homepage. Make sure that you check out the Movileanu Lab at Syracuse University [website]!
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Welcome to the van Oudenaarden Lab homepage, hosted by OpenWetWare. Also check out our [http://web.mit.edu/biophysics/index.html '''''other lab web-site''''']
  
  
'''Email:''' lmovilea@physics.syr.edu
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'''Email:''' avano@mit.edu
  
'''Phone:''' 315-443-8078
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'''Phone:''' (617) 253-4446
  
'''Fax:''' 315-443-9103
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'''Fax:''' (617) 258-6883
  
 
'''Address:'''
 
'''Address:'''
Line 13: Line 13:
 
77 Massachusetts Ave.
 
77 Massachusetts Ave.
  
''Office''
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Bldg. 68-371B (Office)
Room: 211
 
Phone: 315.443.8078
 
Fax: 315.443.9103
 
  
''Lab''
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Bldg. 68-365, 68-359, 68-383 (Labs)
Rooms: B103 and B105
 
Phone: 315.443.0249
 
  
 
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Cambridge, MA  02139
Department of Physics
 
Syracuse University
 
College of Arts and Sciences
 
201 Physics Building
 
Syracuse, New York 13244-1130
 
USA
 
  
 
== Mission ==
 
== Mission ==
test
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Living systems are intrinsically noisy. Surprisingly, the functioning of a living organism is not significantly hindered by these random fluctuations. Biological cells can even exploit noise by deliberately introducing diversity into a population. In these cases noise is not a nuisance, but essential for survival. Advances in modern biochemistry and genetics have led to a detailed understanding of the molecular machinery involved in gene expression, and the constant flow of data from the Genome Project has enabled the identification of more and more genes. A millennial challenge is to quantitatively understand how different genes and their regulating proteins are grouped together in genetic circuits, and how stochastic fluctuations influence gene expression in these complex systems. In our group we focus on the importance of noise in the expression of genes by using both experimental and theoretical approaches.
  
 
== Recent Publications ==
 
== Recent Publications ==
'''2005'''
 
 
*E. M. Ozbudak, A. Becskei, and A. van Oudenaarden, [http://web.mit.edu/biophysics/papers/DEVCELL2005.pdf A system of counteracting feedback loops regulates Cdc42p actvity during spontaneous cell polarization], Developmental Cell 9, 565 (2005).
 
 
*A. Becskei, B. B. Kaufmann, and A. van Oudenaarden,[http://web.mit.edu/biophysics/papers/NG2005.pdf Contributions of low molecule number and chromosomal positioning to stochastic gene expression], Nature Genetics 37, 937 (2005).
 
  
*M. Acar, A. Becskei, and A. van Oudenaarden,[http://web.mit.edu/biophysics/papers/NATURE2005.pdf Enhancement of cellular memory by reducing stochastic transitions], Nature 435, 228 (2005).
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For our recent publications click [http://web.mit.edu/biophysics/papers.html '''''here''''']
  
*J. M. Pedraza and A. van Oudenaarden, [http://web.mit.edu/biophysics/papers/SCIENCE2005.pdf Noise propagation in gene networks], Science 307, 1965 (2005).
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== Lab members ==
  
[http://web.mit.edu/biophysics/papers.html '''''...all publications''''']
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For information on our lab members click [http://web.mit.edu/biophysics/people.html '''''here''''']
  
== [[Van_Oudenaarden_Lab:Members | Lab members]] ==
 
  
 
== [[Van_Oudenaarden_Lab:Internal | Internal lab resource]] ==
 
== [[Van_Oudenaarden_Lab:Internal | Internal lab resource]] ==

Latest revision as of 09:41, 24 December 2007

Alexander van Oudenaarden

Welcome to the van Oudenaarden Lab homepage, hosted by OpenWetWare. Also check out our other lab web-site


Email: avano@mit.edu

Phone: (617) 253-4446

Fax: (617) 258-6883

Address:

77 Massachusetts Ave.

Bldg. 68-371B (Office)

Bldg. 68-365, 68-359, 68-383 (Labs)

Cambridge, MA 02139

Mission

Living systems are intrinsically noisy. Surprisingly, the functioning of a living organism is not significantly hindered by these random fluctuations. Biological cells can even exploit noise by deliberately introducing diversity into a population. In these cases noise is not a nuisance, but essential for survival. Advances in modern biochemistry and genetics have led to a detailed understanding of the molecular machinery involved in gene expression, and the constant flow of data from the Genome Project has enabled the identification of more and more genes. A millennial challenge is to quantitatively understand how different genes and their regulating proteins are grouped together in genetic circuits, and how stochastic fluctuations influence gene expression in these complex systems. In our group we focus on the importance of noise in the expression of genes by using both experimental and theoretical approaches.

Recent Publications

For our recent publications click here

Lab members

For information on our lab members click here


Internal lab resource