- Shireen Rudina
- Cambridge, Massachusetts
- Email me through OpenWetWare
- Feb 2013, BS in Biological Engineering, MIT
- Synthetic biology
- Protein Engineering
- Gene Therapy
I am currently an Organism Engineering intern at Ginkgo Bioworks.
From Jan-Dec 2012, I worked Dr. Chris Voigt's lab at MIT with Felix Moser, where I was working on improving the dynamic range of sensors in genetic circuits through the use of plasmid copy number.
From Sept 2010- Dec 2011, I worked in the Lauffenburger lab at MIT with Dr. Shannon Alford designing an ELISA assay for Mena, a protein upregulated in invasive breast cancer cells. Previously, I studied how the variation in ECM proteins affects the migration and adhesion of invasive breast cancer cells.
During the summer of 2011, I was an Amgen Scholar at Stanford University, and did research in Prof. Christina Smolke's lab with Isis Trenchard, working to engineer S. cerevisiae for the production of bisbenzylisoquinoline alkaloids.
I have also worked on developing a drug-eluting contact lens with Dr. Joe Ciolino in the Langer lab at MIT during January-August 2010.
- Paper1 Gupton et al. Mena binds α5 integrin directly and modulates α5β1 function. pmid= 22908313